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Flashcards in Female Reproductive System And Breast Deck (60):
1

An inflammatory disease characterized by pruritus and dyspareunia and grossly manifests with white plaques and atrophic skin with a “parchment paper” quality.

Lichen sclerosus

2

Lichen sclerosus may be a precursor of what carcinoma

Squamous cell carcinoma

3

The most common form of vaginitis.

Candidiasis (moniliasis)

4

Characterized by white, patch-like mucosal lesions, a thick white discharge, and vulvovaginal pruritus.

Candidiasis

5

The major causative agent for bacterial vaginosis

Gardnerella

6

The most common cause of vaginal discharge.

Bacterial vaginosis (Gardnerella vaginitis)

7

Characteristically, it is a thin, homogeneous vaginal discharge with a malodorous, fishy amine odor, especially on addition of 10% potassium hydroxide.

Bacterial vaginosis (Gardnerella vaginitis)

8

"Clue cells" in the Pap smear

Bacterial vaginosis

9

Causative agent of Lymphogranuloma venereum

C. trachomatis L1, L2, or L3 serotypes

10

Manifests initially as a small papule or ulcer, followed by superficial ulcers and enlargement of regional lymph nodes, which become matted together. It can lead to rectal stricture as a result of inflammatory reaction and scarring.

Lymphogranuloma venereum

11

An infection of the vulva and vagina with the pathognomonic histologic findings of cells with the three “Ms”: multinucleation, nuclear molding, and margination of the chromatin.

Herpes simplex virus (HSV) infections

12

Causative agent for chancroid

Haemophilus ducreyi

13

Vulvar or vaginal infection that is characterized by a soft and painful ulcerated lesion

Chancroid

in contrast to the chancre of syphilis, which is firm and painless.

14

Causative agent for granuloma inguinale

Calymmabacterium (Donovania) granulomatis

15

Donovan bodies are seen in

Granuloma inguinale

16

The most common benign tumor of the vulva.

Papillary hidradenoma


This tumor originates from apocrine sweat glands.

17

Koilocytes are seen in

Condyloma acuminatum


Expanded epithelial cells with perinuclear clearing

18

The most common malignant tumor of the vulva.

Squamous cell carcinoma

19

A benign condition characterized by mucosal columnar epithelium-lined crypts in areas normally lined by stratified squamous epithelium, and is thought to be a precursor of clear cell adenocarcinoma.

Vaginal adenosis

20

A rare variant of embryonal rhabdomyosarcoma with presenting features of multiple polypoid masses resembling a “bunch of grapes” projecting into the vagina, often protruding from the vulva.

Sarcoma botryoides

21

Cervicitis most often involves

Endocervix

22

4 HPV types that are frequently associated with cervical dysplasia or cancer

16, 18, 31, 33

23

Most common cervical cancer

SCC

24

Most common site of endometriosis

Ovary

25

Most common uterine tumor

Leiomyoma (fibroid)

26

Most common tumor in women

Leiomyoma (fibroid)

27

Characterized by islands of endometrium within myometrium

Adenomyosis

28

The most common gynecologic malignancy

Endometrial carcinoma

29

The most frequent benign tumor of the fallopian tubes.

Adenomatoid tumor

30

The l“TICs” (tubal intraepithelial carcinomas), which are thought to be precursors for ovarian serous carcinomas, is associated with mutation in what gene

BRCA-1 mutations

31

This cyst is due to distention of the unruptured graafian follicle.

Follicular cyst

32

This cyst results from hemorrhage into a persistent mature corpus luteum.

Corpus luteum cyst

33

This cyst results from gonadotropin stimulation; it can be associated with choriocarcinoma and hydatidiform mole.

Theca-lutein cyst

34

This cyst is a blood-containing cyst resulting from ovarian endometriosis with hemorrhage.

Chocolate cyst

35

This benign surface epithelial cystic ovarian tumor that is lined with cells similar to fallopian tube epithelium.

Serous cystadenoma

36

Most common ovarian carcinoma

Serous cystadenocarcinoma

37

Pseudomyxoma peritonei is a characteristic of what ovarian tumor

Mucinous cystadenocarcinoma

38

High-grade malignancies and are the most common ovarian tumors seen in association with endometriosis

Clear cell carcinoma

39

Rare, benign tumors that are characterized by small islands of epithelial cells resembling bladder transitional epithelium interspersed within a fibrous stroma

Brenner tumors

40

Tumor analogous to testicular seminoma

Dysgerminoma

41

Tumor marker of endodermal sinus or yolk sac tumor

Alpha fetoprotein

42

Which is malignant? Immature teratoma or mature teratoma?

Immature

43

Most common germ cell tumor

Mature teratoma (dermoid cyst).

44

Most common monodermal teratoma cyst (contains only a single tissue element) that consists entirely of thyroid tissue and can be hyperfunctional, resulting in hyperthyroidism.

struma ovarii

45

This solid tumor consists of bundles of spindle-shaped fibroblasts.

Fibroma

46

A triad of ovarian fibroma, ascites, and hydrothorax.

Meigs syndrome

47

Call exner bodies are diagnostic feature of

Granulosa cell tumor

48

Ovaries are replaced bilaterally by mucin-secreting signet-ring cells

Krukenberg tumors

49

Most common site of origin of Krukenberg tumors

Stomach

50

The most common disorder of the breast

Fibrocystic disease

51

This is the most common breast tumor in women younger than 25 years of age.

Fibroadenomaa

52

Type of fibroadenoma of the breast wherein stroma compresses and distorts glands into slitlike spaces

Intracanalicular fibroadenoma

53

Type of fibroadenoma of the breast wherein the glands retain round shape

Pericanalicular fibroadenoma

54

Breast tumor characterized by cystic spaces containing leaflike projections from the cyst walls and myxoid contents

Phyllodes tumor

55

Most frequent site of carcinoma in the breast

Upper outer quadrant

56

Most common carcinoma of the breast

Invasive ductal carcinoma

57

ER/PR + breast tumor have better or poorer prognosis?

Better

58

Her-2/neu positive breast tumor have better or poorer prognosis?

Poorer

59

Eczematoid lesion of the nipple or areola; with characteristic large cells surrounded by a clear halo-like area, invade the epidermis; underlying ductal carcinoma almost always present

Paget disease of the breast

60

Breast tumor that is often multicentric or bilateral; tends to have cells arranged in a linear fashion (“Indian-file” appearance)

Invasive lobular carcinoma