FENTANYL Flashcards

1
Q

Indications

A

Adjunct to anesthesia

Post operative pain

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2
Q

Class

A

Synthetic opioid analgesic (intermediate - acting)

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3
Q

Mechanism of Action

A

Acts on mu and kappa opioid receptors

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4
Q

Potency

A

100 times more potent than morphine

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5
Q

IV Sedation Dose

A

Sedation Dose: 0.5 - 1 ug / kg IV

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6
Q

Onset

A

IV Immediate

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7
Q

Peak Effect

A

5-6 min

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8
Q

Duration

A

IV 30-60 min

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9
Q

Elimination Half Life

A

3-6 hrs

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10
Q

Elimination

A

Hepatic

Accumulates in larger, prolonged doses

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11
Q

CNS Effects

A

Potent analgesic

Some sedative

NO AMNESTIC

Potentiated by sedatives, volatile anesthetics, NO

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12
Q

CVS Effects

A

Hypotension

Bradycardia

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13
Q

Respiratory Effects

A

Respiratory Depression

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14
Q

GI Effects

A

Nausea, Vomiting, Biliary Tract Spasm, Constipation

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15
Q

MSK Effect

A

Muscle rigidity

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16
Q

IV Induction / RSI dose

A

1-3 ug / kg IV depending on physical status, use of other agents

17
Q

IV Post-operative pain Dose

A

0.5 ug / kg (25-50 ug) q 3