Fertilisationnnnnnn Flashcards

1
Q

Fertilisation
During copulation (), semen is released by ()
The _______ sperms swims , pass , enter into , finally reach
Site of fertilisation

A

Fusion of haploid male gamete with haploid female gamete to form diploid zygote
coitus , penis into vagina ( insemination)
Motile rapidly, through cervix , uterus, ampullarh region of fallopians tube
Ampullary region of fallopians tube

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2
Q

Capacitation ( duration
These occur in
Why not all copulation lead to fertilisation and pregnancy
Arrival of sperm movement
Of secondary occyte

A

Multiple changes that activate sperm for final processes of fertilisation (5-7hr
Sperm on coming in contact with fluids of female genital tract
It can only occur if ovum and sperms are transported simultaneously to ampullary region
Flagellar , ciliated , prostaglandin
Ciliary

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3
Q

Fertilization in male

A

Male -> insemination ( transfer of male gamete into female reproductive tract) -> capacitation of sperm (5-7 hr ) removal of deposit substance from acrosome , entry of ca+2 ion -> arrival of sperm into uterus through cervical canal -> movement of sperm into fallopians tube

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4
Q

Female

Acrosomal reaction

A

Release secondary oocyte -> ovulation -> arrival of secondary oocyte into fallopians tube through infundibulum-> fallopians tube ( ampullary region ) -> fertilisation
Hyaluronidase enzyme = break cementing layer
Corona penetrating enzyme = digest corona radiating layer
Zona lysin enzyme (acrosin) = digest zona pellucida layer

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5
Q

Fertilization main events in sequence and their definition

A

Syngamy = union of male and female gamete
Plasmogamy = intermixing of cytoplasm of male and female gametes
Karyogamy = fusion of pronuclei of male and female gamete
Amphimixis = intermingling of chromosomes of male and female gamete

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6
Q

Fast block polyspermy
Slow block polyspermy
The secretion of acrosome help sperm to enter
Phagocytosis of sperm by, during which

A

Generation of action potential
Due to cortical reaction
Into cytoplasm of ovum through zona pellucida and plasma membrane
Secondary oocyte , completion of second Meiotic division of secondary oocyte to form ovum and second polar body

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7
Q

Cortical reaction produces , ensure
Not dissolved in cytoplasm
Sex of baby determined by

A

Changes in zona pellucida ( makes it hard) that block the entry of additional sperm , only one sperm fertilise the ovum
Nucleus and proximal centriole
Father

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8
Q

Cleavage =
,,,, ( moves through ___cell called
Interphase , results into
1 st cleavage
2nd

A

Repeated Mitotic division
The Mitotic division starts as zygote moves through isthmus of oviduct called cleavage toward uterus and forms 2,4,8,16 daughter cells called blastomeres
Short , ( s phase present) , multicellular embryo without any change in overall size
30 hrs
40 hrs

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9
Q

Morula ,structure ,name , layer
Blastula / ,
Outer layer , inner
What contain stem cell , cavity

A

Embryo with 8-16 blastomeres , solid ball like, resembles mulberry fruit,zona pellucida
Blastocyst = 64 cell stage
Trophoblast , inner group of cell attached to trophoblast called inner mass / embryoblast
Inner cell mass , blastocoel

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10
Q

Blastocyst outer layer gets attached to , inner mass
Embryblast cell attached to trophoblast call
Trophoblast/ responsible for

A

Endometrium , differentiate as embryo
Cell of rauber,
Trophoectoderm for placenta formation

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11
Q

Implantation , starts
Completion , site
Ectopic Pregnancy , by

A

Attachment of blastocyst to endometriosis lining of uterus , 1 week after fertilisation
By day 12 after fertilisation , fundus part
Implantation other than uterus , zona pellucida

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12
Q

Decidua , layers
Gastrulation , formation of ( 1st ,2nd,,
Movement
Trophoblast later forms
Embryoblast

A

Uterus of pregnant mother , decidua basalia , decidua capsularis , decidua parietalis
Transformation of blastocyst into gastrula , 3 germ layer ( endoderm , ectoderm , meso
Morphogenetic
Cytotrophoblast , syncytotrophoblast
Epiblast ( long columnar) , hypoblast ( short cuboidal

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13
Q

Formation of ____… embryonic,,,
Formation of primitive steak (movement)
Fate of germ layer ectoderm
Mesoderm
Endoderm

A

Bilayer , disc
Invagination = epiblast - ectoderm. Hypo some epi = Endo (1st) , middle = meso
Nervous system, sensory organs
Circulatory , excretory , skeletal, reproductive
Digestive , respiratory

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14
Q

Bilaminar embryonic disc
Amniogenic cell from
Formation of yolk sac what formed
Extra embryonic ______ from

A

Epiblast + hypoblast
Trophoblast
Primary yolk sac and endodermal cells of yolk sac
Mesoderm , trophoblast

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15
Q

Formation of extra embryonic coelom peripheral region cell , 2 cell near, cavity (name ) formed between
Chorion outer, inner
Fn
Chorionic frondosum

A

Somatopleuric extra embryonic mesoderm , splanchnopleuric extraembryonicmesoderm
Extra embryonic coelom ( endodermal cell of yolk sac & 1cell
O= endoderm , i = mesoderm
Involve in placenta formation, secrete placental formation
Part of chorion which help in formation of placenta

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16
Q

Amnion outer ,inner
Fn
Yolk sac outer ,inner
Fn
What is same as yolk sac

A

O= mesoderm , I=ectoderm ,
Act as shock absorber ,prevent from desiccation
O= mesoderm, in=endoderm
Formation of blood cells in early embryonic stage
Allantois

17
Q

Extra embryonic coelom

A

Space b/w chorion and amnion

18
Q

Organogenesis end of 1 month
Of 2 month
Of 3 3 month / /
5 month

A

Embryo heart Is formed
Limbs and digits develop
1 trimester / 12 weeks = most of organs are formed , ( limbs , genetial more developed
Appearance of hair on head , first movement start

19
Q

Endo of 6 month //
End of 9 month /
Placenta
Characteristics of placenta

A

24 weeks , 2 trimester = eyelids separate / eyelashes are formed
3 trimester = foetus Is fully developed, ready for delivery
Intimate connection b/w material tissue ( uterine tissue ) and developing foetus
Haemochorial placenta
Metadischorial placenta
Deciduous placenta ( child + placenta

20
Q

Chorionic villi , surrounded by
Chronic villi & uterine tissue forms a
Umbilical cord , fn

A

After implantation, finger like projection appear on trophoblast , uterine tissue and maternal blood
Structural and functional unit between developing embryo (foetus)& maternal body
The placenta is connected to embryo through ,
Helps in transport of substance to and from embryo

21
Q

Fn of placenta ,
,
,
,
,
Placental hormone ,,,,,

A

Nutrition
Exchange of gases
Removal of waste
Act as barrier
Act as endocrine gland
hcG ( humanchorionic gonadotropins) , hpL( human placental hormone) , progesterone,
Estrogen , relaxin

22
Q

hcG =
2
3
hpL =/
Fn

A

Humanchorionic gonadotropins = stimulates corpus luteum for secretion of progesterone & estrogen
Helps prepare mammary gland for lactation
Maintains endometrium during pregnancy
Human placental lactogen / human chorionic somatomammotropin (hCS)
Responsible for development of mammary gland during pregnancy

23
Q

Relaxin fn
2
3
Crh fn
2

A

Dilate pelvic muscle (ileocaceal muscle ) , help in parturition
Increases flexibility of pubic symphysis
Helps dilate uterine cervix during labour
Corticotropin releasing hormone = establishes timing of birth
Increases secretion of cortisol

24
Q

What are produced only during pregnancy
During pregnancy hormones increased
Essential for

A

hCG , hPL, relaxin
Estrogen, progesterone, cortisol, prolactin , thyroxine , hcG,hpL
Supporting foetal growth, metabolic changes in mother, maintained of pregnancy

25
Q

Teratogene
Pregnancy test
Gestation period
Human
Cat
Dog
Elephant

A

Certain agents which cause foetal abnormalities eg certain viruses, drugs , alcohol
Grovidextest
Duration b/w copulation and child birth
9 months +- 7 days ( 270-290 days )
63-65 days
60-65 days
607 - 641 days

26
Q

Parturition / , mechanism , hormones like
Important components of initiation of parturition
Foetal ejection reflex

A

Child birth , complex neuroendocrine mechanism , Crh , cortisol , estrogen, oxytocin,relaxin
Increase in estrogen and progesterone
Signals for parturition originate from fully developed foetus and placenta which induce
Mild uterine contractions

27
Q

Parturition
,
,
,
,
,
,

A

Generation of foetal ejection reflex
Stimulate maternal posterior pituitary
Secretion of oxytocin hormone
Contact myometrin wall of uterus
Secretion of relaxin from placenta
Dilution of pelvic muscle
Child birth

28
Q

Stage of parturition
1 ) duration

A

Stage of dilation ( 8-12 hrs) = release oxytocin
Contract myometruim lining of uterus
Release relaxin
Dilation of pelvic muscle

29
Q

2 stage =
3 stage
Lactation prolactin fn ,,
Oxytocin ,,,
First mother milk , immunity

A

Of expulsion ( 10 min) = expulsion of foetus through birth canal
Placental stage
Milk producing , milk secreting hormone
(Milk let down) Milk ejecting / birth hormone , labour pain
Colostrum (IgA) = passive

30
Q

Twins

A

Monozygotic/ identical twins
Dizygotic / non identical twins/ fraternal twins
Conjoint / Siamese twins