Fertility - Introduction

Question 1

Main causes of infertiliy

Answer 1

• Unexplained infertility (no identified male or female cause) (25%)
• Ovulatory disorders (25%)
• Tubal damage (20%)
• Factors in the male causing infertility (30%)
• Uterine or peritoneal disorders (10%).

Question 2

% cases infertility found in both male and female

Answer 2

40 %

Question 3

Diagnosis of infertility

Answer 3

• 1 year of unprotected intercourse

- Offer earlier investigation to women age 36 and over, or there is a known clinical hx of infertility

Question 4

Cumulative chance of pregnancy after 2 years of trying

Answer 4

90 %

Question 5

Sperm count for infertility

Answer 5

• Semen volume: 1.5 ml or more
• pH: 7.2 or more
• Sperm concentration: 15 million spermatozoa per ml or more
• Total sperm number: 39 million spermatozoa per ejaculate or more
• Total motility (percentage of progressive motility and non-progressive motility): 40% or more motile or 32% or more with progressive motility
• Vitality: 58% or more live spermatozoa
• Sperm morphology (percentage of normal forms): 4% or more.

Question 6

Prediction of ovarian response to IVF

Answer 6

• Total antral follicle count of less than or equal to 4 for a low response and greater than 16 for a high response
• Anti-Müllerian hormone of less than or equal to 5.4 pmol/l for a low response and greater than or equal to 25.0 pmol/l for a high response
• Follicle-stimulating hormone greater than 8.9 IU/l for a low response and less than 4 IU/l for a high response[