Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

MAD Exam 3 > Fever and Rash Viruses > Flashcards

Fever and Rash Viruses Flashcards

(66 cards)

Start Studying
1
Q

molluscum contagiosum structure - nucleic acid

A

large dsDNA, linear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

molluscum contagiosum structure

A

enveloped, complex morphology, HUGE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

molluscum contagiosum replication

A

replicated in cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

molluscum contagiosum clinical course

A

flesh-colored papule with central umbilication (“wart” but not a wart)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

molluscum contagiosum treatment

A

supportive care and IMMUNE RECONSTITUTION (treatment of underlying HIV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

variola (smallpox) structure - nucleic acid

A

large dsDNA, linear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

variola (smallpox) structure

A

enveloped, complex morphology, HUGE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

variola (smallpox) replication

A

replicated in cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

variola (smallpox) clinical course

A

flu-like prodrome, followed by a SYNCHRONOUS vesicular rash (all vesicles in same stage, unlike chicken pox)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

variola (smallpox) vaccine

A

live, attenuated vaccine (not safe for immunocompromised or pregnant)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Mpox (monkeypox) structure - nucleic acid

A

large dsDNA, linear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Mpox (monkeypox) structure

A

enveloped, complex morphology, HUGE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Mpox (monkeypox) clinical course

A

*enanthem (lesions in mouth first sometimes)
*macules to papules to vesicles 1-2 days, then pustules at 5-7 days, then scabs 7-14 days
*rash is PAINFUL
*lesions are firm or rubbery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Mpox (monkeypox) treatment

A

tecovirimat (TPOXX)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Mpox (monkeypox) vaccine

A

live non-replicating attenuating virus JYNNEOS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Parvovirus B19 structure - nucleic acid

A

ssDNA, linear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Parvovirus B19 structure

A

naked, icosahedral (very small)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Parvovirus B19 entry

A

receptor is the P antigen on RBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Parvovirus B19 clinical complications

A

1) aplastic crisis in patients with sickle cell (because it causes lysis of progenitor RBCs)
2) hydrops fetalis and fetal anemia, possible spontaneous abortion, in pregnant women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Parvovirus B19 clinical course - kids

A

childhood exanthem:
*“slapped cheek” or “fifth disease”
*flu-like symptoms
*raised, indurated facial rash, avoiding the mouth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Parvovirus B19 clinical course - adults

A

rash and ARTHRALGIAS due to immune complexes in skin and joints

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

dengue virus structure - nucleic acid

A

ss(+) RNA, linear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

dengue virus structure

A

enveloped, icosahedral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

dengue virus epidemiology and transmission

A

reservoir = monkeys & humans
vector = mosquitoes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
dengue virus clinical course
*BREAKBONE FEVER: -rash -muscle and joint pain -retro-orbital headache -high fever
26
dengue virus CBC results
thrombocytopenia and leukopenia
27
dengue virus testing
*PCR detection *antibody test
28
dengue virus vaccine
*live attenuated tetravalent chimeric vaccine *only give if confirmed PREVIOUS DENGUE INFECTION and living in endemic area
29
why do we only vaccinate those who have already had dengue
ANTIBODY-DEPENDENT ENHANCEMENT causes subsequent infection with a different serotype to lead to more severe disease, including hemorrhagic fever and death
30
yellow fever virus structure - nucleic acid
ss(+) RNA, linear
31
yellow fever virus structure
enveloped, icosahedral
32
yellow fever virus reservoir and vector
reservoir = monkeys and humans vector = mosquitoes
33
yellow fever virus clinical course
*JAUNDICE due to liver damage *high fever *back pain *black vomitus *bloody stools *GI *liver/kidney/heart damage
34
yellow fever virus vaccine
live attenuated vaccine
35
zika virus structure - nucleic acid
ss(+) RNA, linear
36
zika virus structure
enveloped, icosahedral
37
zika virus transmission and epidemiology
reservoir = vertebrates vector = mosquitoes *also, sexual and vertical transmission
38
zika virus clinical course (normal)
*fever *itchy rash *arthralgia *joint pain *conjunctivitis
39
zika virus clinical course - congenital
microcephaly and fetal demise
40
zika virus testing
*PCR detection *antibody test
41
rubella virus structure - nucleic acid
ss(+) RNA, linear
42
rubella virus structure
enveloped, icosahedral
43
rubella virus transmission
respiratory droplets
44
rubella virus clinical course
"German Measles": *erythematous rash starts on face, proceeds to trunk, does not coalesce
45
congenital rubella syndrome
fetus with cataracts, heart defects, developmental delays, hearing loss
46
rubella virus testing
antibody testing
47
rubella virus vaccine
live attenuated "MMR" vaccine (measles, mumps, rubella)
48
measles virus structure - nucleic acid
ss(-) RNA, linear, non-segmented
49
measles virus structure
enveloped, helical nucleocapsid
50
measles virus replication
(-) RNA, so needs a viral RNA-dependent RNA-polymerase protein that is virion associated
51
measles virus transmission
respiratory droplets
52
measles virus clinical course
"4 C's" 1. cough 2. coryza (runny nose) 3. conjunctivitis 4. Koplik spots (on buccal mucosae) FOLLOWED BY RASH FROM HEAD DOWN ("paint poured on head" *becomes confluent
53
measles virus treatment
VITAMIN A otherwise, supportive tx
54
measles virus vaccine
live attenuated MMR vaccine (measles, mumps, rubella)
55
mumps virus structure - nucleic acid
ss(-) RNA, linear, non-segmented
56
mumps virus structure
enveloped, helical nucleocapsid
57
mumps virus replication
(-) RNA, so needs a viral RNA-dependent RNA-polymerase protein that is virion associated
58
mumps virus transmission
respiratory droplets
59
mumps virus clinical course
*bilateral parotitis *fever, headache, malaise COMPLICATIONS: *orchitis (testicular inflammation) *pancreatitis *meningoencephalitis
60
mumps virus vaccine
live attenuated MMR vaccine (measles, mumps, rubella)
61
ebola virus structure - nucleic acid
ss(-) RNA, linear
62
ebola virus structure
enveloped, helical, with filamentous morphology
63
ebola virus replication
(-) RNA, so needs a viral RNA-dependent RNA-polymerase protein that is virion associated
64
ebola virus transmission
contact with bodily fluids, fomites, dead bodies, infected bats/monkeys/apes
65
ebola virus clinical course
*flu-like illness *fatigue, headaches *vomiting/diarrhea *bleeding by stool/mucosa *can have massive hemorrhage, shock
66
ebola virus vaccine
single dose Ervebo vaccine (live)

MAD Exam 3 (28 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions