Filarial Worms Flashcards

(48 cards)

1
Q

Secretory cells of C. philippinensis

A

Stichocyte

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2
Q

Esophageal structure of C. philippinensis

A

Stichosome

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3
Q

C. philippinensis

Adult male

A

Chitinized spicule protected by unspined sheath, caudal alae

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4
Q

C. philippinensis

Adult typical female

A

Oviparous

Uterus with 8-10 eggs arranged in a single row

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5
Q

C. philippinensis

Adult atypical female

A

Oviviparous

Uterus with 40-45 eggs arranged in 2-3 rows

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6
Q

C. philippinensis

MOT

A

Ingestion of infected fish

Autoinfection

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7
Q

C. philippinensis

Typical egg

A

Segmented with thick striated shell and flattened bipolar plugs
Peanut / guitar shaped

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8
Q

C. philippinensis

Atypical egg

A

Multisegmented or embryonated with thin shell and NO polo plugs

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9
Q

C. philippinensis

Pathology

A

MYSTERY DISEASE
Borborygmus (gurgling sound of stomach)
Malabsorption syndrome of fats and sugars
Diarrhea: protein loss, electrolyte loss, dehydration, weight loss
High IgE level

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10
Q

C. philippinensis

IS

A

Larva

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11
Q

C. philippinensis

IH

A

“Ipon” (Sicyopterus sp.)
“Bagsang” (Ambassis miops)
“Birut” (Eliotris melanosoma)
“Buctu” (Chonoporus melanocephalus)

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12
Q

C. philippinensis

Habitat

A

Small intestine

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13
Q

C. philippinensis

Morphology

A

Threadlike worm

Relative of trichuris

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14
Q

C. philippinensis

Lab diagnosis

A
  1. Stool exam- eggs or larva
    a. DFS
    b. AECT, FECT, MIFCT
  2. Dupdenal aspiration
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15
Q

C. philippinensis

Treatment

A

ALBENDAZOLE
Mebendazole
Electrolyte replacement
High protein test

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16
Q

Filarial worm

FH

A

Man

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17
Q

Filarial worm

DS

A

Microfilaria

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18
Q

Filarial worm

IS

A
Filiform larva (L3) / 
Filariform larva
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19
Q

Filarial worm

MOT

A

Arthropod-borne

Bite of an infected vector

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20
Q

Filarial worm

Morphology

A

Threadlike worms

21
Q

Filarial worm

Adult male

22
Q

Filarial worm

Adult female

A

Viviparous

Narrow tail end and pointed

23
Q

Filarial worm

Pathology 1

A

LYMPHATIC FILARIASIS
(Caused mainly by adult worms)
Elephantiasis

24
Q

Filarial worm

Pathology 2

A

MEYERS-KOUWENAAR’S SYNDROME

Lymphadenopathy + hypereosinophilia

25
Filarial worm | Pathology 3
WEINGARTEN'S SYNDROME | Tropical Pulmonary Eosinophilia resembling bronchial asthma
26
Filarial worm | Pathology 4
EXPATRIATE SYNDROME | Immunologic hypersensitivity to mature worms
27
Filarial worm | Lab dignosis
1. BLOOD SMEAR (wet or thick) 2. MEMBRANE FILTRATION TECHNIQUE - heparinized blood - nucleopore filter (5 um) in a Swinney adapter 3. KNOTT'S CONCENTRATION TECHNIQUE - 1 mL blood + 10 mL 2% formalin (lyses RBCS)
28
Filarial worm Lab Diagnosis Miscellaneous
Immunochromatography Antigen detection for circulating filarial antigen (CFA) PCR Ultrasonography
29
Filarial worm | Treatment
Diethyl Carbamazine (DEC) Ivermectin (Stromeclol) Albendazole
30
Wuchereria bancrofti | Common name
Bancroft's filarial worm
31
Wuchereria bancrofti | Vector
Anopheles minimus flavirostris Aedes poecilus Culex quiquefasciatus
32
Wuchereria bancrofti | Habitat
Lower lymph gland
33
Wuchereria bancrofti | Periodicity
Nocturnal 10pm-2pm (peak time) 8pm-4am
34
Wuchereria bancrofti Sheated Microfilaria Cephalic space : breadth ratio
1:1
35
Wuchereria bancrofti Sheated Microfilaria Sheath affinity to giemsa
Unstained
36
Wuchereria bancrofti Sheated Microfilaria Body nuclei
Discrete and separate
37
Wuchereria bancrofti Sheated Microfilaria Nucleus on tail end
None
38
Wuchereria bancrofti Sheated Microfilaria Appearance in blood film
Graceful / smooth curve
39
Brugia malayi | Common name
Malayan filarial worm
40
Brugia malayi | Vector
Mansonia bonnae | Mansonia uniformis
41
Brugia malayi | Habitat
Upper lymph gland
42
Brugia malayi | Periodicity
Nocturnal | Subperiodic
43
Brugia malayi Sheathed microfilaria Cephalic space : breadth ratio
2:1
44
Brugia malayi Sheathed microfilaria Sheath affinity to giemsa
Pink
45
Brugia malayi Sheathed microfilaria Body nuclei
Big and overlapping / | Confluent
46
Brugia malayi Sheathed microfilaria Nucleus on tail end
Two
47
Brugia malayi Sheathed microfilaria Appearance in blood film
Kinky and angular curve
48
Capillaria philippinensis | common name
Pudoc worm