Final Flashcards
(195 cards)
1
Q
meds are primarily metabolized here
A
the liver
2
Q
what affects drug dosage
A
absorption
distribution
metabolism
excretion
3
Q
this is when the drug meets minimum effective concentration
A
drug onset
4
Q
the amount of a drug needed to have a therapeutic effect
A
critical concentration
5
Q
this is when you administer a higher dose to accelerate reaching the critical concentrations, yielding quicker results w/ fewer side effects
A
loading dose
6
Q
what does cephalosporin have cross sensitivity to
A
penicillin (if allergic to penicillin , then could be allergic to this too)
7
Q
what meds should not be given if pt has sulfa allergy
A
glipizide (type 2 DM), thiazide (diuretic), celecoxib (NSAID)
8
Q
box warning for antidepressants (TCAs, SNRI, SSRI, MAOI)
A
suicidality in youth
CNS depression
resp depression
9
Q
box warning for fluoroquinolones (ciprofloxacin)
A
tendonitis / tendon rupture
photosensitivity
damage to cartilage if under 18
10
Q
box warning for tetracyclines
A
pitting / staining of bones & teeth
avoid in children due to bone/teeth damage
11
Q
AE of tetracyclines and DI
A
hepatic effects
DI w/ Digoxin –> dig toxicity
12
Q
which classes of antbx can cause nephrotoxicity
A
aminoglycosides (-mycin, -micin)
cephalosporins (-cef, -ceph)
sulfonamides
lipoglycopeptides
13
Q
what is the recommended duration of anti tubercular therapy before observing the therapeutic effect
what are these 4 meds called
A
rifampin, isoniazid, pyrazinamide, and ethambutol
6 months
14
Q
what drug will cause urine, saliva, sputum, sweat, teeth, tears to turn reddish-orange to reddish-brown color & increase risk for hepatotoxicity
A
rifampin (for TB!)
15
Q
these antiviral meds inhibit tumor growth & replication & fight viral infection
they boost immune system activity which leads to cancer cell destruction
A
interferons
**avoid in autoimmune disease like RA and hepatitis
**dont give live vaccines during this treatment
16
Q
common AE of interferons/interleukins
A
flu like symptoms
17
Q
antidote of acetaminophen
A
acetylcysteine
18
Q
antidote for heparin overdose
A
protamine sulfate
19
Q
antidote for warfarin / Coumadin
A
vit k
20
Q
antidote / reversal agent for cholinergic reactions
A
atropine
21
Q
what drug prevents cell death & tissue damage in cases of norepinephrine or dopamine extravasation
A
phentolamine
22
Q
antidote for benzos
A
flumazenil
23
Q
what to administer to a pt that is in severe resp depression after opioids
A
naloxone (narcan)
24
Q
what med can be used for alcohol withdrawal
A
naltrexone (opioid antagonist)
25
therapeutic level for lithium (mood stabilizer / bipolar)
what med increases risk of toxicity
0.6 - 1.2
thiazide diuretics increase risk of toxicity
toxicity s/s = Generalized convulsions, oliguria, renal failure for severe or can be dizzy, slurred speech, tremors, blurred vision, confusion, delirium
26
these meds are for Parkinson's
dopaminergic (amantadine which is also for flu A, levodopa)
anticholinergic (benztropine)
27
carisoprodol, cyclobenzaprine, chlorzoxazone, metaxalone, methocarbamol, orphenadrine, tizanidine & baclofen (prototype!) are what type of drugs
central acting muscle relaxants
28
prototype for centrally acting muscle relaxants
baclofen
**AE = cns depression, drowsy, sedation, avoid alc & driving
other central acting muscle relaxants include carisoprodol
29
Dantrolene and botulinum toxin products are what type of drugs
direct acting muscle relaxant
30
this medication is extremely hepatotoxic with estrogen
dantrolene which is a direct actin muscle relaxant ... can be FATAL
31
these block opioid receptors without fully activating them to make it useful to treat addiction or reduce the risk of addiction
opioid agonist - antagonist
ex: buprenorphine, nalbuphine (dont give if pt is allergic to sulfites!)
32
what drugs are used for migraines
& pt education for how to take them
triptans and ergots
Ergot pt education – take 2nd dose 30 mins if no improvement
oTriptans- take 2nd dose after 2 hrs if no improvement
32
what drug, if combined with beta blockers, will cause peripheral ischemia and gangrene
ergots !!!! (for h/a)
33
this med is commonly used to treat ventricular tachycardia
lidocaine (se = hypotension, cns depression, bradycardia)
34
where do thiazide diuretics work
distal convoluted tubule
35
this class of diuretics is used for conditions like increased ICP, TBI, glaucoma, acute renal failure rather than htn or HF
osmotic (mannitol!!!) - pulls water into renal tubule without Na loss
SE = CHF, pulmonary edema, dehydration, hypotension, h/a, lightheadedness, electrolyte imbalance
36
what diuretics can cause hypokalemia
thiazide and loop
36
which diuretic can cause hyperkalemia
potassium sparing aka spironolactone
37
which 2 class of meds increase glucose levels
glucocorticoids like prednisone
beta selective adrenergic agonists (beta 2) like isoproterenol, albuterol, salmeterol
38
what does phenazopyridine do
it's a urinary analgesic to relieve UTI pain, does NOT treat it.
take w/ food
only take for 2-3 days bc will cause nephrotoxic and hepatotoxicity
will make pee orange
39
what antispasmodics treat OAB
oxybutynin, tolterodine, darifenacin, solifenacin
40
what are alpha-adrenergic blockers
BPH drugs like doxazosin, tamsulosin, terazosin, alfuzosin
**relaxes everything which can cause hypotension, so pts with low bp should avoid these
41
common undesired side effects associated with metformin, a biguanide medication
diarrhea, bloating
can also have hypoglycemia, lactic acidosis, GI upset, anorexia, heartburn, allergic reaction
41
what are testosterone inhibitors
BPH drugs like finasteride, dutasteride
**can't donate blood or get pregnangy til 6 months after treatment
42
this drug has MOA: decreases heart contractility, preload & after load and cardiac output, along w/ heart rate reduction
used for HF and A-Fib
Digoxin (cardiac glycoside)
43
digoxin therapeutic level
0.5 - 2
44
s/s of digtoxicity
what is treatment
yellow green halo, anorexia, change in vision, confusion, change in heart rate, h/a
treatment = Digfab
45
what meds to hold if HR below 60
beta blockers
cardiac glycosides like digoxin
46
why is warfarin given
venous thrombosis and thromboembolic events like PE / DVT
47
what is amiodarone used for
ventricular tachycardia
**high risk for liver toxicity, & can cause hypotension & bradycardia
48
Nitrates DI
PDE5 inhibitors like sildenafil which cause severe drop in bp
49
when to take HMG-CoA reductase inhibitors (statins) to maximize cholesterol reduction
at night!!!
50
what to monitor when a pt is on HMG-CoA reductase inhibitors (statins)
liver function
51
what med is given during urgent treatment for VTE
also used in DVT, thrombotic strokes, PE
alteplase & tenecteplase (TPA thrombollytic!) to break down thrombi
51
nursing considerations for alteplase & tenecteplase (TPA: trombolytics)
dont give if pt had recent head trauma, surgery or eye surgery
EKG & vital signs are crucial due to hypotension and bleeding & risk for arrhythmias
monitor for petechiae, bruising, dark stool due to bleeding
52
aspirin, mesalamine, olsalazine belong to what class and are used for what
what's important to know about them
salicylates
used for pain relief, fever, preventing platelet aggregation
** stop 1 week prior to surgery, avoid in children or pts w/ recent viral infections due to risk of Reye's syndrome
53
max daily dose of acetaminophen
4g/day
54
these are immune suppressants
immune modulators
T&B cell suppressors
interleukin receptor antagonists
monoclonal antibodies (-mab)
55
common side effect of this drug class is bone pain
drugs = filgrastim, pegfilgrastim, and sargramostim
colony stimulating factors
***boost production of neutrophils in bone marrow to treat neutropenia, cancers, leukemias
56
this is a TNF blockers administered subq
etanercept
57
pt education for taking agents that suppress the immune system like cyclosporine, mycophenolate, corticosteroids
avoid crowds, ppl with infections, working with soil, invasive procedures, preg/lac
**need to use hand hygiene and monitor for s/s of cancer & infection
57
how long does it typically take for topical steroid decongestants to demonstrate improvement in symptoms
2-3 weeks
58
avoid this if taking theophylline (xanthines)
smoking bc it reduces therapeutic levels
also avoid caffeine
59
this is a PRN rescue inhaler
albuterol (SE = palpitations, nervousness, anxiety, tremors)
60
this is a long acting beta agonist for COPD
salmeterol
61
what is salmeterol usually prescribed with to achieve better symptoms control by reducing inflammation in the airways
inhaled corticosteroids
62
pt education for inhaled corticosteroids
rinse mouth after each use to prevent thrush
may take 2-3 weeks before full therapeutic effect
63
these are for non productive cough
dextromethorphan, Benzonatate, codeine, hydrocodone
antitussives
63
this med is contraindicated in narrow-angle glaucoma bc it increases pressure and dilates the pupils
ipratropium (anticholinergic)
64
these are for productive coughs
guaifenesin
*SE = n/v, dizzy, h/a
expectorants
65
what drug is a mucolytic that clears secretions and helps w/ productive cough
acetylcysteine
66
dimenhydrinate (dramamine) and meclizine
first gen antihistamine that treat MOTION SICKNESS
67
this antidiarrheal you cannot take longer than 48 hours
**contraindicated in poisoning and intoxication
loperamide
68
these meds treat nauseas
Antiemetics/serotonergic: Ondansetron
Phenothiazines: Promethazine, prochlorperazine
69
AE of ondansetron
h/a, dizzy, drowsy, myalgia, urinary ret, constipation, diarrhea
70
this is the drug of choice for child vomiting
what is AE
prochlorperazine
(AE = photophobia, drowsy)
71
this works by blocking H2 receptors in the stomach to reduce production of stomach acid
used to PUD, GERD, gastritis
cimetidine
**slow metabolism of most drugs
72
this drug treats shock and can cause tachycardia and htn
isoproterenol (vasopressor)
73
this prostaglandin prevents ulcers induced by NSAIDs
who should refrain from using them
misoprostol
**AVOID IN PREGNANCY...always get preg test prior to taking this bc cat X and is an abortifacient
74
this drug manages shock and can cause htn & tachycardia as well as cardiac arrthymias
dopamine
75
how do non-selective beta blockers affect the heart
decrease cardiac output
76
what med treats DI & how to assess effectiveness
desmopression (synthetic form of ADH)
you'll see a decreased urine output and alleviation of thirst
77
this med if for joint pain and swelling, used in growth deficiencies to help with growth of long bones
SE = bone pain
somatropin
78
when should adrenocortical agents be taken
AM to minimize restlessness and insomnia
79
What medication is commonly used to treat hyperthyroidism and is safe in pregnancy and which one is safe in breast feeding?
propylthiouracil (safe in pregnancy)
Methimazole (lactation)
80
this med is used for hypothyroidism
levothyroxine
81
this med is used to treat osteoporosis and other bone related conditions
**must sit upright for 30 mins after taking it with 8 oz water
alendronate
82
which insulin works the fastest
aspart then lispro
83
which insulin is the slowest acting
glargine
detemir & degludec
84
what med treats severe hypoglycemia
glucagon gel if awake & alert
or IM glucagon or D50 if not alert
85
oral anti diabetic for kids over 10
metformin
86
The nonsteroidal NSAIDs affect the Cox-1 and Cox-2 enzymes. By blocking Cox.-1 enzymes these drugs block
Prostaglandins that protect the stomach lining
87
these meds are used for treatment of RA
methotrexate
entercept
gold therapy
hylan-GF 20
88
Patient is prescribed phenobarbital to relieve anxiety and produce sedation. You should assess the patient for?
Paradoxical excitement
89
Amitriptyline and Imipramine are examples of what type of drug class
TCAs
90
Citalopram, Paroxetine, Sertaline are examples of what type of drug class
SSRIs
91
what is methylphenidate used for
aka (Ritalin) which is for ADHD & narcolepsy
92
why would a female be prescribed androgen
to treat breast cancer
93
this is a class Ib antiarrhthmic and primary blocks sodium influx
lidocaine
94
this is a class II antiarrhthmic
beta 2 receptor blockers
95
these are class IV antiarrhtmics that have unknown action potential
Calcium channel blocker (causes vasodilation)
96
this is the choice for preventing DVT after hip replacement
enoxoparin
97
AE of metroclopramide include
extapyridmal effects
Parkinson like rxns
restlessness
***Treats n/v, GERD... also treats the symptoms of slow stomach emptying (gastroparesis) in patients with diabetes
98
this med treats traveler's diarrhea
rifaximin
99
what is progestin used for
birth control, amenorrhea, uterine bleeding, endometriosis
100
this drug increases bone mineral density in post menopausal female
raloxifene
101
if pt has 485 glucose, what insulin is placed in a drip?
regular
102
what education to give pt prescribed testosterone for androgen deficiency
check labs
monitor for cardiovascular due to increased risk
103
SE of these include testicular atrophy, penile dysfunction, hirituism, gynecomastia, angry, mood changes, acne, high cholesterol, changes in menstruation / decreased ability to conceive for females
anabolic steroids
(athlete abuse these to enhance performance for muscles!)
104
what to monitor for younger pts being treated for hypogonadism
monitor growth & bone formation by taking X-Rays of wrists/hands
monitor cholesterol, CVD is minimal but still important to monitor if on it for a long time
same SE like anger/emotional
105
this decided it's for short term use only for menopausal symptoms like hot flashes & mood swings
why did they decide this?
women's health initiative
decided this bc risks don't outweigh benefits for osteoporosis
106
what classes is prednisone & what to worry about?
mineral and glucocorticoid
worry about hyperglycemia
107
what is important pt education about glyburide (type 2 DM)
what class
what can it cause
take 30 mins TID before meals or it can cause hypoglycemia
sulfonylureas class
don't take if NPO, must be held
108
hallmark side effect of progestins
weight gain (up to 10 pounds due to fluid retention)
also causes h/a, breakthrough bleeding, decreased libido, dysmenorrhea (painful periods)
109
what's important to educate about plan B aka Levonorgestrel
must use within 72 hours
110
contraindications for the use of HRT or any type of BC
importnat pt info?
DI
smoking
hepatic dysfunction
periods of inactivity like surgery or flying
**this doesn't protect you from STDs
DI = tetracyclines & other meds will reduce the effectiveness so need barrier protection
** drugs are tested at 150llbs so heavier pt may need higher dose
111
pt education for PDE5 inhibitors
don't drink w/ alcohol or grapefruit juice bc CYP3A4 inhibitor
don't take nitrates due to severe hypotension & result in cardiac collapse / death
can cause blurred vision / rhinitis
watch out for GU effect such as priapism aka over 4 hours is surgical emergency
112
what is lispro
pt education?
rapid acting insulin (LAG!)
pt education is to give it before meal & make sure they eat
administer subq in fat such as arm, belly, anterior thigh
rotate site at least 2 inches away
don't pull up all at once bc glucose will be different each time
113
this is the oral antidiabetic agent that is approved for use in children over 10
metformin which is a biguanide
114
what to give for a pt with low BG that is minimally responsive
glucagon if unresponsive or give tablet/juice if responsive
115
s/s of thyroid toxicity
tremors
tachycardia
nervousness
116
pt education for bisphosphonates
these is aldendronate & ibandronate for osteoporosis
educate pt to sit upright after taking it for 30 mins w/ a full glass of water
117
2 antithyroid agents
PTU - safe for peds & pregnancies
methimazole - causes bone marrow suppression
118
SE of long term glucocorticoids or mineral
Cushings
osteoporosis
mood disorders
DELAYED WOUND HEALING
118
important pt education for dexamethasone (glucocorticoid)
effects adrenal aka your cortisol so TAKE IN THE AM
119
pt education for oral steroids
avoid large crowds
you're at risk for fungal infection
take bone health supplements & get screenings
don't ever stop abruptly
don't wake w/ NSAIDs bc GI perforation
don't get live vaccines while on steroids
120
what is levodopa for
& what is a SE to report ASAP
for PD to treat tremors
report any tardive dyskinesia
**can cause major arrhythmias, low BP, urinary retention... avoid w/ tyramine foods due to toxicity .. avoid if hx of melanoma bc could exacerbate it.
121
what is desmopressin used to treat
DI (needs ADH!)
122
this is a SABA (short acting beta agonist) used to rescue of asthma attacks, allergic rxns, or used as an emergent
albuterol
123
what needs to be monitored for a pt taking non selective beta blockers
HR
124
what needs to be monitored if pt is on anticholinergic med
I&Os due to fluid retention
125
what needs to be monitored when pt is taking phenylephrine
& what is this drug used to treat
CV such as htn
phenylephrine is used for cold, allergy, pre op hypotension, glaucoma, shock (low BP!)
126
what is dopamine used to treat
& what is SE
treats shock
SE includes arrhythmias (tachy arrhythmia)
127
what is isoproterenol and how does it work
used to treat shock
causes vasoconstriction which will increase BP
128
OTC agent that interacts w/ everything
also effects anticoagulants by increasing risk for bleeding
H2 agonist for heart burn, ulcers, GERD
cimetidine
129
what is misoprostol
what's important regarding this med
prostaglandin that is an abortive agent that will cause bleeding & cramping
always get HCG (preg) test prior to taking it
**also used to treat NSAID induced gastric ulcers
130
this is a serotonin (5HT3) blocker that blocks CTZ receptors
ondansetron
131
what is prochlorperazine and what is a SE
used for n/v , can also treat schizophrenia and anxiety
can cause involuntary movements and photophobia
132
what is loperamide used to treat, & for how long
for noninfectious diarrhea, take it for 2 days max aka 48 hrs
133
this is a first generation anticholinergic used for n/v
what is a SE
meclizine
SE = drys everything
134
these are used for nonproductive coughs
antitussives
135
this is in the methylxanthine class which includes caffeine. patients with COPD used this drug so what should you ask the pt
med was previously favored for treating asthma & bronchospasm but is no longer first choice due to its relatively narrow safety margin
what is therapeutic level
what would severe toxicity cause
what are AE
theophylline aka Xanthine class aka bronchodilator
ask if they're using nicotine bc it increases the effects
therapeutic level of theophylline is 10 - 20mcg/mL
severe toxicity would cause life threatening arrhythmias, hypotension, coma
AE = restless, arrhythmia, palpitations, anorexia, flushing, proteinuria, resp arrest
136
important pt education for nasal steroids & what it treats
they treat allergic rhinitis, takes up to 2 weeks to work
must take every single day, they are NOT PRN
137
antidote for acetaminophen
acetylcysteine
138
antidote for benzodiazepine
Flumazenil
139
antidote for opioids
naloxone aka narcan
140
what is salmeterol black box warning
(long acting beta agonist aka bronchodilator)
increased CVD if not used with inhaled corticoid steroid
141
what is etanercept
what is it used to treat
SE?
TNF blocker that is administered subq
treats RA
SE are flu like symptoms and injection site issues
***allg = Chinese hamster
142
this drug is a colony stimulating factor that's used to treat bone marrow suppression in immunocompromised / cancer pts
what is SE of it
filgrastim
SE = bone pain
143
treatment for hep c
what to educate pt
alpha 2b interferon
educate pt to take Tylenol, use contraceptive, avoid alcohol
144
this is an amino glycoside that causes ototoxicity & nephrotoxicity
gentamycin
145
Gentamicin has a DI with what immunosuppressant drug
cyclosporin (prevents organ rejection) bc can cause nephrotoxicity if taken together
146
med prescribed for organ transplant prophylaxis against rejection and can cause gingival hyperplasia and hirsutism
also prototype for T & B cell suppressors
cyclosporin
avoid crowds, surgeries on this drug due to it being immunosuppressant
also avoid gentamicin w/ this drug bc can cause nephrotoxicity
147
max daily dose of NSAIDs
2400mg/day
take w/ food
can increase bleeding, ulcers, and effect kidneys
increase cardiovascular risks like MI if taken daily
148
pt education for salicylates
under 21 don't give or if pt had recent infection
can cause tinnitus
can inhibit platelet aggregation aka cause bleeding
stop 1 week prior to surgery
149
what increases absorption of iron
what decreases effects?
vitamin C so give w/ citrus juices
antacids, potassium, calcium, dairy, PPIs like omeprazole decreases effects
150
what to monitor if pt is on HMG inhibitor
LFT
cholesterol
151
how do antianginals work
vasodilator to decrease myocardial demand by improving oxygen
ex- nitrates, CCB, BB
152
this is a nonselective adrenergic blocker used for htn, A-Fib, life threatening ventricular arrhythmias
drug class III antiarrhythmic .. Potassium channel blockers
what are the AE to look out for
amiodarone
AE = hypokalemia , liver toxicity, vision problems, lots of DI
contraindicated in thyroid dz
153
what med is good for opioid withdrawal bc it alleviates the symptoms .. also for chronic pain, htn.. it is an alpha selective adrenergic agonist
what is SE
clonidine
SE = fatigue and depression, anxiety, sedation
**labetalol treats clonidine withdrawal
154
this drug is used for ADHD
also treats htn
guanfacine
155
this drug is used for orthostatic hypotension
midodrine
156
indications for Coumadin
heart valves, DVT prevention, A-Fib
157
common SE of digoxin
h/a, nausea, anorexia, irregular HR/rhythm
**watch for vision changes and hold if HR under 60
158
this med increases contractility and decreases HR and workload of heart ... helps heart beat more efficiently
digoxin
159
SE of metformin (biguanide drug!)
GI,,, farty & bloated
160
what is the alpha blocker used to treat BPH
doxazosin
161
this drug is used for OAB, watch out for anticholinergic effects
oxybutynin
162
where do thiazide diuretics work
in the distal convoluted tubule
163
what are ergotamines and triptans used to treat & how?
migraines
they work by vasoconstricting everywhere
164
what is buprenorphine
opioid agonist antagonist .. used for pain & opioid use disorder (reduces the risk of relapse and overdose)... helps get pts off opioids
165
which opioid agonist antagonist is used to relieve pain during labor w/ no issues to the fetus
naloxone (Narcan)
166
these are our recuse meds to reverse effects of opioids
opioid antagonists
naloxone (Narcan)
Naltrexone
167
this is a direct acting muscle relaxant, can be used in MS, stroke, spinal injury to relieve spasms ..
**can also be used for malignant hyperthermia
dantrolene
**fatal AE w/ estrogen on the liver
168
this medication cannot be used with pts on estrogen , HRT , or any birth control due to AE causing fatal damage to the liver
dantrolene (direct acting muscle relaxant)
169
what is baclofen
what is main SE
indirect acting muscle relaxant
SE = dizziness so DON'T DRIVE
170
this is a hydantoin used to treat seizures
what is the therapeutic blood level
SE?
phenytoin
therapeutic blood level 10-20
SE = CNS depression, lethargy, fatigue, constipation, anorexia, dry mouth, hypotension, arrhythmias
***monitor LFT and phenytoin level
171
this class of drugs inhibits reuptake of serotonin & norepinephrine
TCAs (ends in amine, triptylline)
prototype is imipramine
172
therapeutic level for lithium
0.6 - 1.2
173
80% of this drug is reabsorbed through the kidney **** important because this can be toxic if pt has high sodium levels, on diuretics, or dehydrated. Pt needs to be hydrated!!!!!!
what is biggest SE
lithium (therapeutic level is 0.6 - 1.2)
biggest AE = htn crisis
DI = diuretics, NSAIDs bc affect kidneys ... contraindication w/ anyone w/ renal disease
174
what to we give pts w/ constipation from opioid use
methylnaltrexone
175
this is an adjunct agent for seizures , must be tested for preg prior to taking it
valproic acid
176
of the anti seizure meds, which ones are contraindicated for pts w/ kidney issues
Succinimides, specifically w/ kidney stones bc will worsen them
177
Phenobarbital therapeutic drug level
15-40
178
these are used for OCD
what suffix
SSRIs (opram, oxetine, aline)
179
Pt w/ life threatening systemic fungal infection, what is a big medication that is IV only?
Amphotericin B
180
what 2 classes are preferred for hypertensive diabetic pt due to providing renal protection
Ace & Arbs!
Ace inhibitors – prills
*monitor Potassium for hyperkalemia bc aldosterone is effected
Arbs – end in sartan **irbesartan is best for diabetic nephropathy
**both cause cough
**best taken at night!, work best on HDL
181
what is nitroprusside used for
hypertensive crisis (watch out for cyanide toxicity)
182
what med is safest for htn in pregnancy
CCB such as nifedipine
182
what drug class does cholestyramine belong to and how does it work
Bile acid sequestrants
Binds to bile acid intestines, takes bile acid away in the small intestine.. works primarily on LDL
183
this med causes problems w/ kidney function ... it's an ACE inhibitor that prevents conversion of angiotensin to angiotensin II (works in the lungs!)
what to monitor?
SE?
captopril
monitor kidney function and potassium!!!!
weird AE = dysgeusia which is abnormal taste in mouth
184
this TB med can cause peripheral neuropathy
isoniazid
185
what is acyclovir used to treat
bad SE ?
herpes, encephalitis, hair loss
SE = Causes tremors and vertigo, heavy on CNS symptoms
186
If a drug has a half-life of 4 hours and you initially administer 200 mg, what dose will remain 8 hours after administration?
50 mg remaining bc 200 / 2 / 2 = 50
only divide it twice bc 4 + 4 = 8 so two times.
187
The time it takes for the amount of drug in the body to decrease to 1/2 of the peak level it achieved
half life
