Final Flashcards
(39 cards)
How do you reduce a triple bond to a trans DB?
Na, NH3
What reduces ketones but not esters?
NaBH4, H3O+
Go over aldol reaction steps
What do products of aldol condensations look like?
What does -OD, D2O do?
Replaces mark CH with CD
What makes bromides react quickly by SN1 mechanism?
Being adjacent to DB C to there’s resonance
What does NaNH2 do to 3x bond?
Adds - charge to end
What does H2SO4, HgSO4, and H2O do?
Adds DB O to mark
Why does anisole (OCH3) brominate faster than benzene?
Resonance of methoxy stabilizes cationic intermediate.
What factors make something more open to bromination?
Resonance, stable intermediate
Decreasing reactivity to HNO3/H2SO4
CH3, none, Br, COOH
What does MeBr do?
Adds to - charge
What does H2, Pt do?
Removes DB. Cis
What does KCN do?
Subs CN
What does LiAlH4 do?
Strong reducing
Is NO2 an OP or meta director?
Meta
Br2, FeBr3
Adds Br at mark
How do you remove NO2?
H2, Pt. NaNO2, cold
What makes stuff more reactive to NaOH?
Resonance, good LG.
What parts of molecules react with intramolecular aldol?
What states are in a keto enol tautomerization?
Ketone and alcohol
- Cl2, NaOH
- H2O, H+
Swaps methyl for OH
What makes stuff react faster on benzene with subs?
Multiple OP directors with overlapping zones
Reversible nucleophile addition
NaCN, HCN
