Final

Question 1

Mechanism/s for cell damage in type II hypersensitivity

Answer 1

All of the above

classical complement cascade, natural killer cells, opsonization

Question 2

incompatible blood transfusion could induce a hemolytic reaction that results in intravascular lysis of the rbc’s, and release of _____ from lysed cells.

Answer 2

hemoglobulin

Question 3

the lack of immune response for self -antigens in the tissue is caused by:

Answer 3

A and B

deletion of self reactive cells, inactivating the cell (anergy)

Question 4

T/F function of T suppressor cells is important in suppression

Answer 4

true

Question 5

antibodies against antibodies called _____

Answer 5

anti-idiotype antibody

Question 6

T/F in graves disease antibodies in the blood, the TSH (thyroid stimulating hormone) receptors on the thyroid gland

Answer 6

true

Question 7

which of the following autoimmune disease is associated with butterfly rash on the face?

Answer 7

systemic lupus

Question 8

which of the following factors is/are involved in insulin dependent diabetes mellitus autoimmune disease?

Answer 8

A and B

infection, HLA gene

Question 9

which one of the following biochemical/s is/are going to be reduced in hashimoto’s thyroiditis?

Answer 9

thyroxin

Question 10

which of the following is called rheumatoid factor?

Answer 10

IgM-antibody against F-c portion of a patients own IgG

Question 11

autoantibodies in double-stranded DNA are typical findings in which of the following disorders?

Answer 11

Systemic Lupus erythematosus

Question 12

multiple sclerosis is associated with which of the following types of hypersensistivity reactions?

Answer 12

IV and III

Question 13

the antibodies in warm agglutinin type immune hemolytic anemia consist of which of the following classes of immunoglobulins?

Answer 13

IgG

Question 14

allografts of lymphoid tissue are particularly immunogenic because of the high content of

Answer 14

MHC class II expressing cells

Question 15

An example of a type III immune complex disease is

Answer 15

Rheumatoid arthritis and (SLE) Scleroderma

Question 16

the localized reactions to infected antigens in the same body site such as booster shot are called

Answer 16

Arthus reaction

Question 17

a positive tuberculin skin test is an example of

Answer 17

a delayed type allergy

Question 18

contac dermatitis is causes by

Answer 18

chemical absorbed by the skin

Question 19

a graft transplanted between individualS That are members of different species

Answer 19

xenograft
(allographt same species
autograft same individual
isograft (syngraft) genetically identical. same species, i.e. twins)

Question 20

factors that affecting the immune system and decrease the immune functions are as follow

Answer 20

A and C

• chronic disease
• emotional stress

Question 21

T/F patient with severe immunodeficiency disease in both T- cells and B-cells compartment accept a allogenic bone marrow graft

Answer 21

true

Question 22

natural antibodies have the following characteristics

Answer 22

all of the above

low affinity, low specificity, harmless, have some rule for clearing infection

Question 23

in natural tolerance 95% of apoptisis (PCD) of T cells found in

Answer 23

thymus

Question 24

central tolerance is within _____

Answer 24

thymus

Question 25

Post streptococal (glomerulonephritis)

Answer 25

immune complex disease

Question 26

arthus reaction

Answer 26

Type III hypersensitivity (local)

Question 27

serum sickness

Answer 27

type III hypersensitive (systemic)

Question 28

contact hypersensit-IV-ity

Answer 28

type IV

Question 29

T suppressor cells prevent ____ to make antibodies, and also prevent ______ from maturing into T-cytotoxic cells

Answer 29

B-cells, T cells

Question 30

T/F prexisting infections can have positive or negative effects on immune response

Answer 30

true

Question 31

this is an induced tolerance in which an animal will fail to respond to non-self antigens (all exogenous antigens) from outside the body that would normally be immunologic

Answer 31

acquired tolerance

Question 32

which of the following factors are involved in autoimmune disease

Answer 32

All of the above | infection, hormonal, genetic

Question 33

these monkey antigens (Rh factor) are presenting in __ of humans and absent in the other ___

Answer 33

85%, 15%

Question 34

transfusion reaction may cause

Answer 34

all of the above