Final

Question 1

One 1 table spoon is equal to:

a. 5ml
b. 15ml
c. 10ml
d. 20ml

Answer 1

15 ml

Question 2

This agency regulates the manufacture and distribution of substances that have a potential for abuse such as narcotics, stimulants, and sedatives.

Answer 2

DEA Dug Enforcement Agency

Question 3

This is the production of a compound by the combination of two like molecules:

covalent bonding
stereoisomerism
depolarization
dimerization

Answer 3

dimerization

Question 4

What schedule of drug can be purchased over the counter?

I
II
III
V

Answer 4

V

Question 5

This legislation requires Caution: Federal law prohibits dispensing without a prescription.

harrison narcotic act 1906
durham humphrey law of 1952
controlled substance act of 1970
food and drug act of 1906

Answer 5

durham humphrey law of 1952

Question 6

On children’s dosing, weight x adult does/150 is which formula:

fried’s rule
young’s rule
clark’s rule
cowling’s rule

Answer 6

clark’s rule

Question 7

This type of hypersensitivity reaction is considered a delayed type and is mediated by T-lymphocytes.

type I
type II
type III
type IV

Answer 7

type IV

Question 8

Most drugs are excreted from the body via

glomerular filtration
active tubular secretion
passive tubular secretion
bilary excretion

Answer 8

bilary secretion

Question 9

Which of the following is not associated with Phase I metabolism?

oxidation
reduction
hydrolysis
depolarization

Answer 9

depolarization

Question 10

Which chemical bond is the most effective force in attracting a drug molecule to a receptor?

covalent bond
van Der Waals forces
ionic bonds
hydrogen bonds

Answer 10

ionic bonds

Question 11

This 2nd messengers is involved in conduction of smell and sight:

Answer 11

cyclic 3’5’ adenosince monophosphate (cAMP)

Question 12

This is the study of drugs:

Answer 12

pharmacology

Question 13

This is the dose of a drug required to produce a specific effect in 50% of the subjects taking it:

Answer 13

ED50

Question 14

This is a function of the amount of a drug required to produce an effect:

potency
efficacy
half life

Answer 14

potency

Question 15

Which of the following antagonists binds to receptor site that is different from binding site for the agonist?

competitve antagonist
non competitve antagonist
physiologic antagonist

Answer 15

non competitve antagonist

Question 16

Which of the following is not an advantage of a parenteral route of administration:

cheap
fast
rapid onset
predictable response

Answer 16

cheap

Question 17

Which layer of a transdermal patch is the closet to the skin:

impenetrable membrane
drug reservoir
adhesive
membrane

Answer 17

adhesive

Question 18

Which route is the most rapid absorption of a drug into the systemic circulation:

inhalation
subcutaneous
topical
sublingual

Answer 18

sublingual

Question 19

Which type of drug easily penetrates the blood brain barrier:

Answer 19

a highly lipid-soluble, non-ionized drug

Question 20

On a log dose effect curve, a drug that is more potent will be:

closer to y axis
closer to x-axis
farther away from the y axis
farther away from the x-axis

Answer 20

closer to the y axis

Question 21

Which of the following is not one of the 6 most important neurotransmitters:

serotonin
histamine
noepinephrine/epi
cAMP

Answer 21

cAMP

Question 22

The asymmetric carbon in a racemic mixture is called a

Answer 22

chiral center

Question 23

Which of the following factors influencing the movement of a drug is the bodies way of changing a drug so that it can be better used and removed by the kidneys:

absorption
distribution
metabolism
excretion

Answer 23

metabolism

Question 24

Which category of adverse drug reactions is an extension of the pharacologic effect resulting from a drugs effect on the target organ:

drug allergy
side effect
idiosyncratic reaction
toxic reaction

Answer 24

toxic reaction

Question 25

All of the following can write a Rx for a controlled substance except: ``` MD DMD DVM FNP all of the above can ```

Answer 25

FNP

Question 26

The maximum intensity of effect or response produced from a drug: efficacy potency lethal dose duration

Answer 26

efficacy

Question 27

A nicotinic cholinergic receptor found in a skeletal muscle is an example of: voltage gated ion channel receptors ligand gated ion channel receptors cGMP linked receptors cAMP linked receptors

Answer 27

ligand gated ion channel receptors

Question 28

If drug A has a half life of 2 hours, how long before it is out of the system:

Answer 28

8-10 hours

Question 29

A therapeutically useful drug is one with a TI of

Answer 29

10.0

Question 30

Four steps of absorption of n orally administered drug:

Answer 30

disruption disintergration dispersion dissolution IV- skip all 4 steps

Question 31

Prego categories

Answer 31

A B C D X

Question 32

Three of the four drugs contraindicated in pregnancy:

Answer 32

tetracycline NSAIDS birth control

Question 33

bid

Answer 33

twicea day

Question 34

prn

Answer 34

as needed

Question 35

PO

Answer 35

by mouth

Question 36

tid

Answer 36

3 times per day

Question 37

q

Answer 37

every

Question 38

qid

Answer 38

4 times a day

Question 39

disp

Answer 39

directions to the pharmacist

Question 40

h

Answer 40

hour

Question 41

Heroin

Answer 41

Schedule I drug

Question 42

Valium

Answer 42

Schedule IV drug

Question 43

Tylenol #3

Answer 43

Schedule III drug

Question 44

Morphine

Answer 44

Schedule II drug

Question 45

Inscription

Answer 45

name of drug, dose form, amt.

Question 46

Subscription

Answer 46

directions to the phamracist

Question 47

Transcription

Answer 47

directions to the patient

Question 48

A schedule II Rx must be written in ink.

Answer 48

True

Question 49

A schedule I drug can purchased OTC

Answer 49

Flase

Question 50

Schedule III/IV drugs can be refilled up to 5 times in 6 months

Answer 50

True

Question 51

A rx must have the name of the medication and its strength

Answer 51

True

Question 52

The basic metric unit for measurement of weight is the milligram

Answer 52

False

Question 53

The therapeutic index is figured by dividing the ED50 by the LD50

Answer 53

Flase

Question 54

No drug is free from producing some adverse efffect in a certain number of people

Answer 54

True

Question 55

When dosing children, it is best to follow the schedule prepared by the manufacturer

Answer 55

True

Question 56

Most drugs are eliminated via feces

Answer 56

Flase

Question 57

The IV route produces the most rapid drug response with an almost immediate onset of action

Answer 57

True

Question 58

Administration of topical steroids over a large portion of the body can lead to systemic toxicity known as:

Answer 58

Cushings

Question 59

Non opiods include all of the following except: salicylates NSAIDS codeine acetaminophen

Answer 59

codeine

Question 60

This term means to reduce fever: synergism salicylism pruitis antipyretic

Answer 60

antipyretic

Question 61

What is the LD50 of aspirin for children:

Answer 61

4 gms

Question 62

Which drug is contraindicated with aspirin because it cauases excess bleeding:

Answer 62

NSAID

Question 63

Which of the following drugs requires the least amount of dosing for pain: ibuprofen naproxen codeine bromefenac

Answer 63

naproxen