Final Exam

Question 1

First line treatments for agitation and aggression in dementia

Answer 1

SSRIs and SNRIs

Question 2

What antipsychotic has best evidence for agitation in dementia

Answer 2

Risperidone

Question 3

First line treatment for panic disorder for a patient with a history of substance use disorder

Answer 3

FDA approved: fluoxetine, paroxetine, sertraline

Question 4

Psychiatric disorders affected by a deficit in GABA

Answer 4

Anxiety, panic disorder, insomnia, seizure disorder

Question 5

Warrants lifeline antidepressant maintenance

Answer 5

Having 3 ore more episodes of MDD

Question 6

Adequate antidepressant medication trial

Answer 6

4-6 weeks

Question 7

Significant side effect of trazodone

Answer 7

priaprism

Question 8

FDA approved medications for treatment of panic disorder

Answer 8

Paxil

Xanax

Question 9

Side effect of Effexor for doses greater than 300 mg

Answer 9

Hypertension

Question 10

Which medication blocks formation of fear conditioning/anxiety in victims of trauma

Answer 10

propranolol

Question 11

Neurotransmitters associated with depression

Answer 11

Serotonin, Norepinephrine, Dopamine

Question 12

neurotransmitters associated with antipsychotic medication

Answer 12

*dopamine, serotonin, histamine

Question 13

Difference between MDD and dysthymia

Answer 13

MDD = symptoms for two weeks
dysthymia = persistent depression over 2 years

Question 14

Serotonin role in depression

Answer 14

Mood, emotions, hunger, sex, sleep

Question 15

Patient education for antidepressants

Answer 15

Don’t stop abruptly
Can take up to 8 weeks to take effect
watch for SI

Question 16

Most common mistake when prescribing antidepressants

Answer 16

Too low of dose for too short a time

Question 17

Interventions for decreased sex drive

Answer 17

Add bupropion (Wellbutrin)

Question 18

Most common SSRI to cause discontinuation syndrome

Answer 18

Paxil (paroxetine)

Question 19

Discontinuation syndrome symptoms

Answer 19

flu-like symptoms

Question 20

SSRIs with highest risk of D2D interactions

Answer 20

fluoxetine (prozac)
fluvoxamine (Luvox)
Paroxetine (Paxil)
Duloxetine (Cymbalta)

Question 21

MAOIs

Answer 21

Nardil (phenelzine)
Parnate (Tranylcypromine)
Marplan (Isocarboxazid)
Selegiline (Eldepryl)

Question 22

Side effects of MAOI

Answer 22

orthostatic hypotension
insomnia
weight gain
tyramine induced hypertension

Question 23

MOA of MAOI

Answer 23

monoamine oxidase inhibitors:

Inhibit breakdown of norepinephrine, serotonin, epinephrine, dopamine, and tyramine

Question 24

foods to avoid with MAOIs

Answer 24

fermented food, alcohol, cured meats, bananas, avocados, figs, raisins, chocolate, yeast, aged cheese

Question 25

NDRI

Answer 25

wellbutrin (bupropion)

Question 26

Increases serotonin and norepinephrine AND blocks H1 receptors leading to weight gain and sleep

Answer 26

mirtazapine and trazodone

Question 27

MOA of TCAs

Answer 27

Blocks reuptake of norepinephrine and serotonin and blocks acetylcholine

Question 28

Main side effects/risks with TCAs

Answer 28

LOTs of D2D interactions (CYP450 inhibitor) Anticholinergic effects sedation, weight gain, hypotension teratogenic

Question 29

antidepressant for bulemia

Answer 29

Fluoxetine (Prozac)