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MH701 Psychopharmacology > Module 2 Antidepressants > Flashcards

Module 2 Antidepressants Flashcards

1
Q

Prolongs QT

A

Celexa (citalopram)

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2
Q

FDA approved for OCD

A

Luvox (flluovoxamine)

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3
Q

Boosts serotonin and norepinephrine

A

Effexor (venlavaxine)

Cymbalta (Duloxetine)

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4
Q

Main adverse SE of venlafaxine (Effexor)

A

Hypertension

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5
Q

Helps increase appetite
a2 Adrenergic receptor antagonist
increases norepinephrine and serotonin

A

Mirtazapine (Remeron)

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6
Q

increases dopamine and norepinephrine

A

Bupropion (Wellbutrin)

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7
Q

Increases seizure threshold

A

Bupropion (Wellbutrin)

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8
Q

Serotonin antagonist and reuptake inhibitor

A

Trazodone

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9
Q

Widened QRS complex, lethal in overdose, effects sodium and calcium channel ions

A

TCAs -amitriptyline (pain), imipramine (bedwetting)

clomipramine (OCD)

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10
Q

Wash out period for most SSRIs?

fluoxetine?

A

2 weeks

5-8 weeks

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11
Q

MAOIs main adverse side effect

selegiline, Phenelzine

A

Hypertensive crisis if given with tyramine (wines and cheeses)

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12
Q

response

A

50% of improvement of symptoms

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13
Q

remission

A

removal of essentially all symptoms for the first 6 months

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14
Q

Recovery

A

symptom free for 6 months or more

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15
Q

Depression symptoms return before full remission of symptoms or within the first several months following remission of symptoms

A

Relapse

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16
Q

depression symptoms return after a patient has recovered

A

recurrence

17
Q

Most commonly causes discontinuation syndrome

A

paxil (paroxetine)

Effexor (venlafaxine)

18
Q

Least likely to cause discontinuation syndrome

A

Prozac (fluoxetine)

19
Q

Most common SSRI to cause weight gain

A

Paxil (paroxetine)

20
Q

Weight neutral antidepressants

A

Wellbutrin (bupropion)

Fluoxetine (Prozac)

21
Q

Most sedating SSRI

A

Paxil (paroxetine)

22
Q

Can be used to reduce sexual side effects of SSRIs

A

Bupropion (switched to or added on)

Sildenafil (in men)

23
Q

NMDA antagonist - increases glutamate

A

ketamine

24
Q

Learning and memory part of brain

A

hippocampus

MH701 Psychopharmacology (19 decks)

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