Final Exam Flashcards
(229 cards)
Explain the anatomy of the brain
The brain consists of two types of cells: neurons and glia.
Neurons are individual cells in the nervous system that receive, integrate, and transmit information.
Activity of neurons is significant and relates to an organism’s behavior
what are some qualities of Glial Cells
Glia are cells found throughout the nervous system and they provide various types of support for neurons.
Smaller than neurons
Human brain has equal parts neurons and glial
What are some types of Glial Cells
There are many different types of glial cells and they have a wide range of critical functions. For example, some act like parents, providing nutrition, healing, protection, and physical support for the neurons. Some act like cleaners, removing debris from the brain. Some act like a miniature Pac Man from a video game, devouring dead and damaged cells.
What are the 3 ways Glial Cells provide protection to the brain
Provide protection to the brain in 3 ways
Produce cerebrospinal fluid. Cerebrospinal fluid (CSF) is a colourless fluid surrounding the brain and spinal cord. It has several functions, including serving to cushion the brain during an impact.
Second, they form the blood–brain barrier, which prevents foreign material, including some viruses and drugs, from entering the brain.
Third, they contribute to the immune system of the brain.
How do Glial Cells contribute to braincells
The glial cells provide the neurons with nutrients and energy from the blood. Glial cells provide structure for the neurons, holding them in place and forming scar tissue if the brain is injured.
glial cells also insulate the neurons, allowing them to process information faster and with less energy.
How do Glial Cells contribute to major disorders
Research shows that glial cells play a role in a variety of major disorders.
For example, dysfunction in glial cells may contribute to the cognitive impairment seen in schizophrenic disorders (Wang et al., 2015) and to some forms of depressive disorders
what are some qualities of neurons
there are roughly 86 billion neurons in the human brain
A synapse is a junction where information is transmitted from one neuron to the next.
A vast majority of neurons communicate only with other neurons. However, a small minority receive signals from outside the nervous system (from sensory organs) or carry messages from the nervous system to the muscles that move the body.
what are the five common properties of neurons
Neurons have 5 common properties
First, all neurons have a barrier, like a skin, that separates the inside of the cell from the outside. This barrier, called the cell membrane, has small channels or gates that allow, or prevent, molecules from entering or leaving the cell. This will become important when we
Second, each neuron has a cell body, also called a soma, which contains the nucleus and acts like a tiny factory where proteins and neurotransmitters (or at least the building blocks of neurotransmitters) are manufactured. (The word soma comes from the Greek word meaning body.) The cell body is where information from thousands of other cells is gathered and sorted out.
Third, all cells have dendrites, which gather much of the incoming information from other cells. Dendrites are the structures that branch out from the cell body. (Dendrite is a Greek word for tree.) Their main purpose is to increase the surface area of the neuron so that chemicals, released from thousands of other cells, can influence the activity of the neuron that the dendrites belong to.
Fourth, in addition to the many dendrites that branch out from the cell body, each neuron has a single main extension called the axon. The axon is a long, thin fibre that transmits signals away from the soma to other neurons or to muscles or glands. The axon’s main role is to conduct a brief electrical charge away from the cell body. Unlike dendrites, which are just a few millimeters in length, axons can be relatively long. For example, some axons that control movement connect the brain to the spinal cord and can be a meter in length. Some axons may be several meters long in a giraffe.
Fifth, though only one axon leaves each cell body, this axon can branch and each branch ends in an axon terminal. Axon terminals are where chemicals are released by the neuron to influence the activity of other neurons.
what are the purpose of axons
In humans, many axons are wrapped in cells with a high concentration of a white, fatty substance called myelin. The myelin sheath is insulating material, derived from specialized glial cells.
When the myelin sheath is intact it helps to stabilize the axon structure and the patterns of connectivity in the neural network. It contributes to two big advantages.
First, it speeds up the transmission of signals that move along axons
The second benefit of the myelin sheath is that it is very efficient.
what are the four processes that explains the activity of neurons
The activity of neurons can be understood by examining four processes: resting potential, action potential, synaptic transmission, and graded potentials.
explain resting potential
RESTING POTENTIAL
The resting potential of a neuron is its stable, negative charge when the cell is inactive.
To create and maintain the resting potential, two ions are critical: potassium (K+) and sodium (Na+). There are small openings in the cell membrane, called gates or channels, which allow potassium to move more easily in and out of the cell. There are channels for sodium (Na+) as well, but they are usually closed.
Without the resting potential, the brain would not allow us to think, feel, learn, or move.
explain action potential
ACTION POTENTIAL
action potential, which is a very brief shift in a neuron’s electrical charge that travels along an axon.
absolute refractory period, which is the minimum length of time after an action potential during which another action potential cannot begin.
A limiting factor in the speed of the action potential is the size of the axon. Axons with a larger diameter have less resistance, so the speed of the action potential can be increased.
explain Synaptic tranmission
Basically, each neuron makes a chemical and stores it in the terminal buttons. When a neuron is sufficiently stimulated, an action potential causes the chemical to be released into very tiny gaps between the neuron and adjacent neurons. These gaps are referred to as synaptic clefts.
These chemicals, known as neurotransmitters, transmit information from one neuron to another.
Explain transportation and storage neurotransmitters
Transportation and storage. When molecules of the neurotransmitter are made, they are transported from the cell body to the axon terminal where they are stored. They are stored in small bead-like containers called synaptic vesicles.
explain the release neurotransmitter
Release. When an action potential in the neuron reaches the axon terminal, the synaptic vesicles melt into the cell membrane, causing the release of the neurotransmitter into the synapse (Schwarz, 2008). Because this part of the membrane is before the synapse, it is called the presynaptic membrane.
explain the binding neurotransmitter
- Binding. The released molecules of neurotransmitter float across the gap and some bind with the membrane of the cell after the synapse. The molecules bind to specialized proteins called receptors. These receptors allow the molecules to influence whether this next cell, the postsynaptic cell, will have its own action potential. A specific neurotransmitter can bind only to receptor sites that its molecular structure will fit into, much like a key must fit a lock.
explain autoreceptor activation neurotransmitter
- Autoreceptor activation. Some neurotransmitters bind to receptors on the same neuron that released it. This type of receptor is called an autoreceptor. Autoreceptors only respond to neurotransmitters that have been released by the same neuron on which it is situated. Binding on these presynaptic receptors can regulate Steps 1 and 3. For example, this binding can decrease the synthesis and release of the neurotransmitter.
explain reuptake neurotransmitter
Reuptake. Leftover and excess neurotransmitter molecules can be brought back in to the presynaptic region of the cell. This is one of the original recycling mechanisms. By taking the extra molecules out of the synapse, this can stop the effect of the neurotransmitter on the postsynaptic cell and reduce the amount of neurotransmitter that the presynaptic cell must make.
explain degradation neurostransmitter
Degradation. Given that you are continually synthesizing neurotransmitters (Step 1) and recycling used neurotransmitters (Step 7), there needs to be a mechanism to ensure that you don’t end up with too much. Enzymes in the presynaptic region break down excess neurotransmitter molecules, which are then eliminated.
what is the nature of all 8 steps of Synaptic transmission
The first four steps of synaptic transmission share a common purpose; they all increase the influence of the presynaptic cell on the postsynaptic cell. The last four steps share a common purpose as well; they are all involved in stopping the presynaptic cell from continuing to influence the postsynaptic cell.
What are graded potentials
The final process is the trigger that takes a neuron from its resting potential to an action potential. This trigger is called the graded potential
what are some patterns of neural activity
Normal development is characterized more by the elimination of old synapses appears than the creation of new synapses. The nervous system normally forms more synapses than needed and then gradually eliminates the less-active synapses
individual neurons do not influence behavior but that they are linked in complex networks he called cell assemblies. He formulated the Hebbian learning rule; when a neuron stimulates another neuron repeatedly, this produces changes in the synapse between them.
Long-term potentiation refers to a long lasting increase in neural excitability in synapses along a specific neural pathway.
how do neurons influence other neurons
neurotransmitters are molecules that are released from the presynaptic region to allow one neuron to influence the firing rate of another neuron.
what are 4 common properties of neurotransmitters and their influences
4 common properties of neural transmitters
1. They are synthesized in the neuron.
2. They are stored in the synaptic terminals.
3. They are released when the neuron has an action potential.
4. They are deactivated or removed from the synapse when they have completed their task.
Neurotransmitters have only one of two effects when they are released into the synapse. They either increase the chance of the postsynaptic cell firing (i.e., they produce excitatory postsynaptic potentials) or they decrease the chance of the postsynaptic cell firing (i.e., they produce inhibitory postsynaptic potentials).