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Infectious disease drug cards > Final exam > Flashcards

Final exam Flashcards

(107 cards)

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1
Q

Azithromycin brand name

A

Zithromax, Z-pak

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1
Q

Azithromycin class

A

Macrolide antibiotic

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2
Q

Azithromycin dosage form

A

tablet and powder for oral suspension

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3
Q

Azithromycin on-label

A

Acute infective exacerbation of COPD, skin or tissue infection; Bacterial sinusitis; Chancroid, nongonococcal cervicitis; Community-acquired pneumonia; Sexually transmitted infections; Streptococcal pharyngitis

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4
Q

Azithromycin off-label

A

Traveler’s dirrhea

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5
Q

Azithromycin BBW

A

None

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6
Q

Azithromycin CI

A

Hypersensitivity to macrolides or ketolide antibiotic

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7
Q

Azithromycin adverse effects

A

Diarrhea, nausea, vomiting

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8
Q

Clarithromycin brand name

A

Biaxin

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9
Q

Clarithromycin class

A

Macrolide antibiotic

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10
Q

Clarithromycin dosage form

A

tablet, suspension and ER

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11
Q

Clarithromycin on-label

A

Acute infective exacerbation of bronchitis; Community-acquired pneumonia; Disseminated infection due to M . avium-intracellulare; H. pylori GI tract infection; Streptococcal pharyngitis-group A; COPD, acute exacerbation

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12
Q

Clarithromycin off-label

A

Bacterial endocarditis prevention for high risk patients

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13
Q

Clarithromycin BBW

A

None

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14
Q

Clarithromycin CI

A

Hypersensitivity to any macrolide or ketolide antibiotic; concomitant colchicine, cisapride, pimozide, astemizole, terfenadine, ergotamine, dihydroergotamine, or HMG-CoA reductase inhibitors metabolized by CYP3A4/5, history of cholestatic jaundice/hepatic dysfunction with use of clarithromycin, colchicine in renal or hepatic impairment

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15
Q

Clarithromycin adverse effects

A

taste disturbance

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16
Q

Erythromycin brand name

A

Erythrocin

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17
Q

Erythromycin class

A

Macrolide antibiotic

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18
Q

Erythromycin dosage form

A

capsule, tablet (DR), suspension

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19
Q

Erythromycin on-label

A

Bacterial infection

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20
Q

Erythromycin off-label

A

Chlamydia trachoma’s infections, uncomplicated; Nongonococcal urethritis

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21
Q

Erythromycin BBW

A

None

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22
Q

Erythromycin CI

A

Concurrent use with ergotamine, terfenadine, astemizole, lovastatin, simvastatin, cisapride

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23
Q

Erythromycin adverse effects

A

Diarrhea

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24
Doxycycline brand name
Vibramycin, Doxy 100
25
Doxycycline class
Tetracycline antibiotic
26
Doxycycline dosage form
powder for oral suspension, tablet, capsule, syrup
27
Doxycycline on-label
Acinetobacter infection; Acne vulgaris; Gonorrhea, uncomplicated; Staphylococcal infection of skin; Pneumonia, community-acquired
28
Doxycycline off-label
Lyme disease prevention; Prosthetic joint infection; Otitis media, acute; Cellulitis, mild to moderate
29
Doxycycline BBW
None
30
Doxycycline CI
Hypersensitivity, concurrent retinoic acid derivatives
31
Doxycycline adverse effects
Esophageal injury; Photosensitivity, skin hyperpigmentation, tooth discoloration in children <8 yo
32
Minocycline brand name
Minocin
33
Minocycline class
Tetracycline antibiotic
34
Minocycline dosage form
tablet, capsule
35
Minocycline on-label
Acne vulgaris; allergy to penicillin-bacterial infectious disease
36
Minocycline off-label
None
37
Minocycline BBW
none
38
Minocycline CI
hypersensitivity
39
Minocycline adverse effects
dizziness and vertigo, tooth discoloration in children <8 yo, headache
40
Clindamycin oral brand name
Cleocin
41
Clindamycin class
Lincosamide antibiotic
42
Clindamycin dosage form
capsule, granules for oral solution
43
Clindamycin oral, on-label
Bacterial infectious disease (streptococci; staphylococci; pneumococci); Infection of skin; Infectious disease of abdomen; Lower respiratory tract infection; Pelvic inflammatory disease; Septicemia; Osteomyelitis; Diabetic foot infection
44
Clindamycin off-label
Bacterial vaginosis; Streptococcal pharyngitis, penicillin-allergic patients; Prosthetic joint infections
45
Clindamycin oral BBW
Colitis
46
Clindamycin oral CI
Hypersensitivity
47
Clindamycin oral adverse effects
Nausea
48
Albendazole brand name
Albenza
49
Albendazole class
Antihelmintic
50
Albendazole dosage form
tablet
51
Albendazole on-label
Parenchymal neurocysticercosis caused by Taenia solium
52
Albendazole off-label
Ancylostoma caninum (round and hookworm); Enterobius vernicularis (pinworm); Giardiasis; Chinese liver fluke worm; Cutaneous larva migrans; Gnathostomiasis and microsporidiosis; Oesophagostomum bifurcum; Toxocariasis; Trichinellosis
53
Albendazole BBW
None
54
Albendazole CI
Hypersensitivity to albendazole or benzimidazole
55
Albendazole adverse effects
Headache, elevated LFTs
56
Acyclovir brand name
Zovirax
57
Acyclovir class
Viral DNA polymerase inhibitor
58
Acyclovir dosage form
capsule, tablet, suspension
59
Acyclovir on-label
Genital herpes simplex, herpes zoster (shingles), varicella (chickenpox); cold sores
60
Acyclovir off-label
Herpes simplex prevention in immunocompromised patients
61
Acyclovir BBW and CI
None and Hypersensitivity
62
Acyclovir adverse effects
Malaise
63
Valacyclovir brand name
Valtrex
64
Valacyclovir class
viral DNA polymerase inhibitor
65
Valacyclovir dosage form
tablet
66
Valacyclovir on-label
Genital herpes simplex; herpes zoster (shingles); varicella; herpes labials (cold sores)
67
Valacyclovir off-label
CMV prevention in allogeneic stem cell transplant; herpes simplex or varicella zoster in cancer patients; bell palsy, new onset, adjunctive therapy
68
Valacyclovir BBW and off-label
None and hypersensitivity
69
Valacyclovir adverse effects
Malaise, headache, nausea, neutropenia, nasopharyngitis, increased LFTs
70
Atazanavir brand name
Reyataz
71
Atazanavir class
antiretroviral agent, protease inhibitor
72
Atazanavir dosage form
capsule and powder
73
Atazanavir on-label
Treatment of HIV-1 in naive patients, patients with prior virologic failure and pregnant patients
74
Atazanavir off-label
none
75
Atazanavir BBW and CI
None and hypersensitivity
76
Atazanavir adverse effects
Rash, hyperlipidemia, elevated LFTs, abdominal pain, elevated bilirubin level, cough, fever
77
Efavirenz brand name
Sustiva
78
Efavirenz class
antiretroviral agent, reverse transcriptase inhibitor
79
Efavirenz dosage form
capsule and tablet
80
Efavirenz on-label
Treatment of HIV-1 infection
81
Efavirenz off-label
none
82
No BBW for Efavirenz; CI are?
Hypersensitivity or concurrent use of bepridil, cisapride, elbasvir, grazoprevir, midazolam, pimozide, triazolam, St. John’s wort, or ergot alkaloid
83
Efavirenz adverse effects
Anxiety, dizziness, insomnia, headaches, rash, nausea, vomiting, diarrhea, hyperlipidemia
84
Emtricitabine/Tenofovir Disoproxil brand name
Truvada
85
Emtricitabine/Tenofovir Disoproxil clas
antiretroviral agent, reverse transcriptase inhibitor
86
Emtricitabine/Tenofovir Disoproxil dosage form
tablet
87
Emtricitabine/Tenofovir Disoproxil on-label
treatment of HIV-1 infection in combination with other antiretrovirals; preexposure prevention of HIV-1
88
Emtricitabine/Tenofovir Disoproxil off-label
Treatment of hepatitis B; Postexposure prevention for HIV-1
89
Emtricitabine/Tenofovir Disoproxil BBW
Hepatitis B exacerbation, lactic acidosis, drug resistance with preexposure prophylaxis
90
Emtricitabine/Tenofovir Disoproxil CI
Do not use for preexposure prophylaxis in patients with unknown or HIV-1 positive status. Only for use in combination with other antiretrovirals
91
Emtricitabine/Tenofovir Disoproxil adverse effects
Hyperpigmentation, rash, hypophosphatemia, nausea, diarrhea, abdominal pain, weakness, cough, rhinitis, dizziness, headache, insomnia, fatigue, decreased bone mineral density
92
Maraviroc brand name
Selzentry
93
Maraviroc class
antiretroviral agent; CCR5 antagonist
94
Maraviroc dosage form
tablet and solution
95
Maraviroc on-label
treatment of CCR5-tropic HIV-1 infection
96
Maraviroc off-label
none
97
Maraviroc BBW
Hepatotoxicity, severe rash, allergic reaction
98
Maraviroc CI
Patients with CrCl <30 mL/min or ESRD who are taking potent CYP3A4/5 inhibitors or inducers
99
Maraviroc adverse effects
Fever, rash, URI, cough, vomiting
100
Raltegravir brand name
Isentress
101
Raltegravir class
antiretroviral agent, integrase inhibitor
102
Raltegravir dosage form
tablet; chewable tablets; oral packet
103
Raltegravir on-label
Treatment of HIV-1 infections
104
Raltegravir off-label
Occupational and nonoccupational HIV postexposure prevention
105
Raltegravir BBW and CI
None and Hypersensitivity
106
Raltegravir adverse effects
Elevated LFTs

Infectious disease drug cards (4 decks)

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