final exam Flashcards
the body’s ability to resist disease, involving recognition and elimination of pathogens.
immunity
Engulfing and digesting microbes by cells like neutrophils, monocytes/macrophages, and dendritic cells
phagocytosis
Process of marking pathogens with opsonins (e.g., antibodies or C3b) to enhance phagocytosis.
opsonization
Movement of immune cells toward the site of infection in response to chemical signals.
chemotaxis
“Cluster of Differentiation” markers are surface proteins used to identify immune cell types
CD markers
Non-specific, no memory, and immediate response. which immunity?
innate
Skin, mucous membranes, saliva, tears, stomach acid, normal flora are what of the innate immune system
external defenses
Neutrophils, Macrophages, Dendritic cells, Eosinophils,
Basophils, Mast cells, and
NK cells are what of the innate immune system ?
internal defences
macrophages and neutrophils do what as an internal defense
Phagocytosis
dendritic cells are what
potent APC
basophils and mast cells release what in a allergic reaction
histamine
which cells in the innate internal defense system destroy virus-infected and tumor cells?
NK cells
What triggers NK cells to phagocytize?
cytokines/ lack of MHC antigens
immunity that is specific, has memory, and is delayed
adaptive immunity
what are the 2 branches of adaptive immunity
cellular (T cell mediated) and humeral (B cell mediated)
CD markers for cellular immunity
CD4 and CD8
what is the function of cytotoxic T cells? CD8
kill infected cells
what is the function of helper T cells?CD4
Activate B cells and other immune cells.
humeral immunity is made up of which cell?
b cell (lymphs)
CD markers for humeral immunity (B cells)
CD 19, 20, 21
what is the B cell lymphs function
produce antibodies
what are plasma cells and their function
Differentiated B cells that secrete antibodies.
what is the function of t reg cells?
Suppress the immune response to self-antigens
and other harmless Ag (regulates)
one of the Acute phase reactants; has a role in opsonization; monitored in
infection/inflammatory response
CRP