Final Exam 4

Question 1

HSV/VZV Encephalitis and Severe Disseminated VZV Tx

Answer 1

• IV Acyclovir
• Acyc AE: Nephrotoxocity

Question 2

HAV Tx

Answer 2

• Supportive care, no antivirals

Question 3

HBV Tx

Answer 3

• TAF, TDF, or Entacavir

Question 4

Gonorrhea - Weight ≥150kg

Answer 4

• Ceftriaxone 1 g IM x 1dose
• if chlamydia (not excluded): Add Doxy x7d or Azithro x1dose (A if pregnant)

Question 5

Anti-HBc (+)
IgM Anti HBc (-)

Answer 5

Chronic infxn

(if both positive, acute infxn)

Question 6

Neurosyphilis

Answer 6

• DOC: Aqueous crystalline PCN G IV q4h x10-14days

Question 7

HBsAg Positive

Answer 7

the pt is INFECTED

Question 8

“-Vir-“

Answer 8

NNRTI

Question 9

“-Buvir”

Answer 9

NS5B Protease-i

Question 10

Trichominiasis

Answer 10

• Women or HIV+: Metro 500mg BID x7days
• Men: Metro 2g x1dose

Question 11

Early Latent Syphilis (<1 year duration)

Answer 11

• DOC: Benzathine PCN G 2.4 IM x1dose

Question 12

Primary and Secondary Syphilis

Answer 12

• DOC: Benzathine PCN G 2.4 IM x1dose

Question 13

Anti-HBs positive

Answer 13

the pt is IMMUNE

Question 14

Anti-HBc positive

Answer 14

the pt has been EXPOSED to the virus

Question 15

Only Anti-HBs positive

Answer 15

pt is immune due to vaccine

Question 16

“-Previr”

Answer 16

NS3/4A Protease-i

Question 17

Tertiary Syphilis

Answer 17

• DOC: Benzathine PCN G 2.4 IM qweekly x 3 weeks

Question 18

Velpatasvir

Answer 18

• HCV Tx
• NS5A Protease-i
• pts w/ genotype 3 MUST screen for Y93H substitution –> VEL/SOF/VOX (if present)

Question 19

Elbasvir

Answer 19

• HCT Tx
• NS5A Protease-i
• pts w/ genotype 1a, MUST screen for presence of resistance-associated substitutions (RAS)

Question 20

Late Latent Syphilis (>1 year duration) or unknown duration

Answer 20

• DOC: Benzathine PCN G 2.4 IM qweekly x 3 weeks

Question 21

“-Asvir”

Answer 21

NS5A Protease-i

Question 22

TAF, TDF, and Entacavir AE’s

Answer 22

• potential ALT flares on withdrawal

Question 23

“-Gravir”

Answer 23

Integrase Strand Transfer-i

Question 24

Staph Aureus Bacteremia (SAB)

Answer 24

Empiric Tx: Vanc or Dapto (D in pts w/ septic pulmonary emboli)
- MSSA SAB: Nafcillin, Oxacillin, Cefazolin IV
- 14 days after FIRST Negative BC
- NEVER PO Tx

Question 25

IgM Anti-HBc positive

Answer 25

pt has been exposed within the last 6 months

Question 26

"-Navir"

Answer 26

Protease-i

Question 27

Gonorrhea - Weight <150 kg

Answer 27

- Ceftriaxone 500 mg IM x 1dose - if chlamydia (not excluded): Add Doxy x7d or Azithro x1dose (A if pregnant)