Final Exam Chapter 8 Flashcards Preview

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Flashcards in Final Exam Chapter 8 Deck (41):
1

What are functions of the gallbladder

Store bile and concentrate bile

2

What bile is primarily bile from the liver

Hepatic bile

3

What bile is concentrated bile from the gallbladder

Cystic bile

4

What is bile release controlled by

CCK and the vagus nerve

5

What is the surface epithelium of the gallbladder mucosa

Simple columnar

6

What cell types are located within the gallbladder mucosa

Clear cells and brush cells

7

What cells are aka cholangiocytes, have many microvilli, and function to concentrate bile by absorbing water

Clear cells

8

What cell is few in number within the gallbladder mucosa and produce mucinogen

Brush cells

9

What part of the gallbladder often posses small mucous glands

The neck of the gallbladder lamina propria

10

What part of the gallbladder mucosa is loose and very vascular ct

Lamina propria

11

What is the function of the lamina propria of the gallbladder

Lubricate the narrow neck lumen

12

What part of the gallbladder mucosa is absent

Muscularis mucosa

13

Is there submucosa in the gallbladder

No its absent - unusual

14

What is unique about the muscularis eterna of the gallbladder

It is NOT a normal pattern, has thin smooth muscle layer with disorganized muscle arrangement

15

What is the difference between endocrine and exocrine pancreas

Endocrine = islets of langerhans producing hormones, exocrine = serous acini producing digestive enzymes

16

What is the largest portion of the pancreas

Exocrine (digestive enzymes) portions

17

What do pancreatic ducts do for the exocrine pancrease

Secretion (H2O and HCO3) controlled by secretin and acetylcholine from parasympathetic nerves

18

What type of cell is characteristic of pancreatic ducts

Centroacinar cells

19

What type of pancreatic duct cells are with cuboid cells in intercalated pancreatic ducts and what do they produce

Centroacinar cells producing alkaline fluid with large amounts of bicarbonate to release into duodenum to buffer stomach chyme

20

What wraps the pancreatic ducts and what is the function

Collagen rich ct = provide extra protection from possible leaking of digestive enzymes

21

What is the largest gland in the body with endocrine and exocrine functions

The liver

22

What are 5 functions of the liver

Metabolize lipids/carbs/protein, production of blood proteins/vitamins, detoxify blood, produce hepatic bile (exocrine) store vitamines (A,B12)

23

What type of cell are hepatocytes

Microvilliated cuboidal cells possesing lateral bile between adjacent hepatocytes

24

How does bile go through a liver lobule (bile canaliculi)

Bile moves from hepatocytes towards the bile duct bronchi in the portal triad

25

What cell is arranged in rows between hepatic sinusoids like spokes of a wheel

Hepatocytes

26

What is another name for kupffer cells and what do they develop from

Stellate macrophages that develop monocytes

27

What do kupffer cells do

Phagocytosis of debris and aged RBC’s, act as APC

28

What cells are known as hepatic stellate cells

Ito cells

29

What cells store lipids, vit A, produce collagen 1,3,4 and growth factors

Ito cells

30

What are pit cells

Natural killer cells

31

What are hepatic progenitor cells responsible for

Present regenerative capabilities

32

What is the portal triad

Includes branches from hepatic artery, portal vein, and bile duct

33

What cell is dilated, fenestrated and found between rows of hepatocytes

Hepatic sinusoids

34

What do hepatic sinusoids carry

Mixture of venous (75%) and arterial blood (25%)

35

What is fenestrated and collects blood from hepatic sinusoids

The central vein

36

Where does the central vein receive blood flow from

The portal triad

37

What is another name for space of disse

Perisinusoidal space

38

What is the space of disse

Space between hepatocytes and fenestrated hepatic sinusoids where blood directly contacts microvilliated surfaces of hepatocytes

39

Where is flow slow enough so cells can interact with blood and its contents

The space of disse (perisinusoidal space)

40

Why can the liver take over functioning for the spleen for 24-48 hours

Because of slow flow in space of disse

41

What is glisson’s capsule made of

Dense irregular CT covered with serosa, other ct limited in human liver