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Bio 150 > Final Exam part 1 > Flashcards

Final Exam part 1 Flashcards

1
Q

What is the nature of science?

A

to ask questions that can be answered by observing or measuring things

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2
Q

What are the dependent and independent variable on a graph?

A

independent- x-axis
dependent- y-axis

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3
Q

what are the steps of the scientific method?

A

observation/question, research topic area, hypothesis, test with an experiment, analyze data, report conclusions, repeat…

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4
Q

What is a hypothesis?

A

a proposed explanation based on limited evidence and used as the starting point for developing an experiment. Should be precise and testable

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5
Q

What is a null hypothesis and what is its purpose?

A

It states that the hypothesis is not the explanation. It makes the scientist be able to see if the data collected was by random chance or not

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6
Q

What is the control of an experiment?

A

It is the basis for which comparisons are made during an experiment, the group left unchanged.

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7
Q

What is DNA?

A

Deoxyribonucleic acid

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8
Q

What stores the genetic information in cells?

A

DNA

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9
Q

What is a nucleic acid?

A

a polymer made up of monomers called nucleotides

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10
Q

What was the Hershey-Chase experiment?

A

An experiment that determined that DNA stores genetic material, not proteins as previously thought

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11
Q

What do T2 proteins contain (used in the Hershey-Chase experiment)?

A

sulfur

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12
Q

What does DNA contain (used in the Hershey-chase experiment)?

A

phosphorous

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13
Q

What is a polymer?

A

a substance consisting of repeating subunits (monomers)

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14
Q

What is a nucleotide?

A

a phosphate group bonded to a 5carbon sugar which is bonded to a nitrogenous base

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15
Q

What are the single-ring nitrogenous bases?

A

cytosine, uracil, and thymine

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16
Q

What are the double-ringed nitrogenous bases?

A

guanine and adenine

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17
Q

What is the primary structure of DNA?

A

a directional sugar-phosphate backbone

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18
Q

What is the secondary structure of DNA?

A

an anti-parallel double helix

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19
Q

What was the Watson & Crick experiment?

A

discovered the sugar-phosphate backbone of DNA, and discovered the rules of nitrogenous base pairings

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20
Q

What did Rosalind Franklin and Maurice Wilkins do?

A

Used x-ray crystallography to determine that DNA has a helical shape

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21
Q

What is complementary base pairing?

A

adenine to thymine, guanine to cytosine

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22
Q

Where is DNA found in eukaryotes?

A

chromosomes

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23
Q

What is DNA replication?

A

Using the genetic code of DNA to synthesize new DNA

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24
Q

DNA replication is ______

A

semi-conservative

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25
Q

What is meant by DNA replication is semi-conservative?

A

parental strands separate, and each are used as a template strand for a new daughter strand

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26
Q

What are the steps of DNA replication?

A
  1. replication bubble forms at the origin of replication
  2. DNA synthesis proceeds in the 5’ to 3’ direction, adding nucleotides at the 3’ end
  3. Active DNA synthesis takes place at the replication forks of the bubble
  4. synthesis occurs on both strands of the template DNA at the replication forks
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27
Q

What direction does DNA synthesis occur in the leading strand?

A

5’ to 3’ or towards the replication fork

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28
Q

What direction does DNA synthesis occur in the lagging strand?

A

3’ to 5’ or away from the replication fork

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29
Q

What is the central dogma?

A

DNA (transcription) mRNA (translation) proteins

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30
Q

What happens during transcription?

A

RNA polymerase uses a template DNA strand to a complementary nucleotide to the growing mRNA strand in the 5’ to 3’ direction (adds to the 3’ end)

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31
Q

Is mRNA single or double stranded?

A

single

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32
Q

What is translation?

A

The use of mRNA as a genetic code to produce protein

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33
Q

What is the genetic code?

A

The coding for amino acids produced when 3 base pair triplets are read

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34
Q

What are codons?

A

3 base pair triplets

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35
Q

What is the start codon?

A

AUG

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36
Q

What are the features of the genetic code?

A

It is redundant, unambiguous, non-overlapping, (nearly) universal, and conservative

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37
Q

What is a gene?

A

A section of DNA which codes for a protein

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38
Q

What are chromosomes?

A

Organized DNA that are made of a single long DNA double helix wrapped around histone proteins

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39
Q

What is a chromatin?

A

Complex of DNA which codes for a protein

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40
Q

What is a locus?

A

The physical location of a gene on a chromosome

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41
Q

What is an unreplicated chromosome?

A

A single, long DNA double helix wrapped around histone proteins

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42
Q

What is a replicated chromosome?

A

Consists of two copies of the same DNA double helix

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43
Q

What is a diploid cell?

A

A cell containing two sets of chromosomes

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44
Q

What is a haploid cell?

A

A cell containing one set of chromosomes

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45
Q

What are alleles?

A

Different versions of the same gene

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46
Q

What is gene expression?

A

Set of processes that converts the information in DNA into the product of a gene

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47
Q

What is a genotype?

A

The alleles of a gene present within a single organism

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48
Q

What is the one gene - one polypeptide hypothesis?

A

each gene contains information to produce one protein

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49
Q

What is a phenotype?

A

A detectable trait of an organism

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50
Q

What is an important exception to the central dogma?

A

Many genes code for RNA’s that function directly in the cell

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51
Q

What does heterozygous mean?

A

Containing two different alleles of the same gene

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52
Q

What does homozygous mean?

A

Containing two of the same alleles of the same gene

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53
Q

What is a dominant allele?

A

When the phenotypic effect can be seen anytime the allele is present

54
Q

What is a recessive allele?

A

The phenotypic effect can only be seen in homozygous individuals

55
Q

What is a mutation?

A

Any permanent change in an organism’s DNA

56
Q

What is a point mutation?

A

A mutation that alters the sequence of one or a small number of base pairs

57
Q

What is a silent mutation?

A

Change in the nucleotide sequence that does not alter the amino acid specified

58
Q

What is a missense mutation?

A

A change in the nucleotide sequence that does alter the amino acid specified by the codon (can be beneficial, deleterious, or neutral)

59
Q

What is a nonsense mutation?

A

A change in amino acid sequence that results in an early stop codon (AUG)

60
Q

What is a frameshift mutation?

A

The addition or deletion of a nucleotide (almost always deleterious)

61
Q

What is chromosome mutation?

A

A larger scale mutation that changes either the structure or the number of chromosomes

62
Q

What is a deletion?

A

When broken segments of a chromosome get lost

63
Q

What is an inversion?

A

When broken chromosomes are flip and rejoined

64
Q

What is duplication (chromosome mutation)?

A

One or more additional copies of a segment

65
Q

What is translocation?

A

When a broken piece becomes attached to a different chromosome

66
Q

What is the blending inheritance hypothesis?

A

Traits of a mother and father blend together to form offspring

67
Q

What are pure-breeding lines?

A

Lines that produce offspring identical to the parents

68
Q

What are hybrids?

A

Offspring from matings of two true breeding parents that differ in one or more trait

69
Q

What is a monohybrid cross?

A

Breeding between pure-breeding lines that are homozygous for different alleles of the same trait

70
Q

What is the particulate inheritance hypothesis?

A

Hereditary determinants are discrete and maintain their integrity from one generation to the next

71
Q

What is the principle of segregation?

A

Two members of each gene must segregate into different gametes

72
Q

What is independent assortment?

A

Alleles of different genes do not stay together when gametes form

73
Q

What are the traits of homologous chromosomes?

A

Same size and shape, contains the same genes at the same loci, and the DNA sequence is not identical

74
Q

Are gametes haploid or diploid?

A

Haploid

75
Q

What happens during meiosis I?

A

Cells replicate each of their chromosomes into sister chromatids. Then homologous chromosome are separated into daughter cells

76
Q

What happens during meiosis II?

A

Sister chromatids separate and become individual chromosomes. The daughter cell now has a copy of each chromosome

77
Q

Independent assortment of chromosomes into gametes creates _______.

A

New combinations of alleles

78
Q

What does crossing over do?

A

Produces new populations of alleles within a chromosome

79
Q

What is a population?

A

A group of individuals within a species living in the same space or geographic areas

80
Q

What can be studied about populations?

A
  1. How populations change over time in size and in trait frequencies
  2. How populations of the same species in different locations vary
  3. How individuals within one population may vary
  4. How the environment influences the population
81
Q

There is variation among individuals in almost all populations. What kind?

A

phenotypic, genotypic, and allele

82
Q

Where does variation come from?

A

Mutations, crossing over, genetic recombination into gametes, and random fertilization

83
Q

What is a gene pool?

A

All alleles present within a population

84
Q

What are gene pools characterized by?

A

Genotypic frequencies and allele frequencies

85
Q

What does Hardy-Weinberg state?

A

Within a population, if:
1. The population is infinitely large,
2. Mating is random
3. There is no natural selection
4. No mutations occur
5. No migration occurs
Then the trait under study will be in Hardy-Weinberg Equilibrium

86
Q

What is the equation for Hardy-Weinberg Equilibrium?

A

p^2 + 2pq + q^2 = 1

87
Q

What is evolution?

A

The change in allele frequencies in a population over time (occurs when a population is not in Hardy-Weinberg Equilibrium)

88
Q

What are the four mechanisms of evolution?

A
  1. mutation (weak force)
  2. gene flow (strength depends on degree of movement)
  3. genetic drift ( strong effect on small populations)
  4. Natural selection (most powerful force)
89
Q

What is gene flow?

A

When an individual or gametes move between populations

90
Q

What is genetic drift?

A

When chance events determine which alleles are passed to the next generation

91
Q

What is the bottleneck effect?

A

large -> small -> large, usually occurs when a natural disaster wipes out a large amount of a population

92
Q

What is the founders effect?

A

When a few individuals isolate from a large population and form a new population, resulting in a random subject of new allele within the new population

93
Q

What is positive assortative mating?

A

When similar genotypes are more likely to mate than dissimilar ones (increases homozygosity)

94
Q

What is negative assortative mating?

A

When dissimilar genotypes are more likely to mate than similar ones (increases heterozygosity)

95
Q

What is inbreeding?

A

Mating between related individuals (increases homozygosity)

96
Q

What is an inbreeding depression?

A

When related individuals mate causing a decrease in survival and fertility of offspring

97
Q

What was Plato’s “perfect essence”?

A

Claimed that every organism was an example of a perfect essence, created by god and that type was unchanging

98
Q

What is typological thinking?

A

Classifies things only in terms of the types they belong to and view variation as abnormal

99
Q

What was Aristotle’s “great chain of being”?

A

Species were fixed types organized into a sequence based on size and increasing complexity.

100
Q

What was the law (theory) of use and disuse?

A

The more an organ is used, the larger and stronger it gets. The less it is used, the more the organ deteriorates

101
Q

Who created the law of use and disuse and the law of inheritance of acquired characteristics ?

A

Jean-Baptiste Lamarck

102
Q

What was the law (theory) of inheritance of acquired characteristics?

A

All the losses or acquisitions shaped by nature on an individual are preserved by the reproduction of new individuals

103
Q

Who was Charles Darwin?

A

Described variation among individuals within a population, and across closely related species

104
Q

What is natural selection?

A

A process through which certain characteristics survive and reproduce at a higher rate because of those characteristics

105
Q

What does natural selection lead to?

A

adaptations

106
Q

Natural selection is a major force for driving what?

A

allele frequency change

107
Q

Natural selection is the chief mechanism for ______.

A

transforming populations

108
Q

What is fitness?

A

The ability of an organism to survive and reproduce compared to other individuals of a populations

109
Q

What are the requirements of the theory of evolution by natural selection?

A
  1. Variation
  2. Inheritance
  3. Struggle for existence
  4. Differential survival and reproduction
110
Q

What is an adaptation?

A

A characteristic of an organism that improves fitness within its environment

111
Q

What are the types of natural selection?

A

directional selection, stabilizing selection, and disruptive selection

112
Q

What is directional selection?

A

Individuals at one phenotypic extreme are favored

113
Q

What is stabilizing selection?

A

Individuals with an intermediate phenotype are favored

114
Q

What is disruptive selection?

A

Individuals at both phenotypic extremes are favored

115
Q

How do we determine if natural selection is occurring within a population?

A

We have to determine if the trait arising is increasing an individual’s fitness

116
Q

What measures can we use to quantify fitness?

A

direct and indirect measures

117
Q

What is a direct measure?

A

survival rates and number of offspring

118
Q

What are some indirect measures?

A

Health, body size, etc…

119
Q

What are common misconceptions about natural selection?

A
  1. Natural selection changes individuals
  2. Natural selection is goal oriented
  3. Natural selection leads to perfection
  4. natural selection is the only process of evolution
120
Q

What is sexual selection?

A

Selection because of preference by one sex for certain characteristics of individuals of another sex

121
Q

What is intersexual selection?

A

Selection because of characteristics (non-random) called mate choice

122
Q

What is intrasexual selection?

A

Selection through competition (non-random).

123
Q

What can intersexual selection cause?

A

sexual dimorphism

124
Q

What is the Bateman-Trivers Hypothesis?

A

Production of eggs is more costly than the production of sperm, so females should be choosy and protect themselves.

125
Q

What are honest signals?

A

Traits that signal health and quality

126
Q

Sexual selection and natural selection can conflict such that ______________.

A

traits preferred in mating decrease survival

127
Q

Mutations are random in regards to __________.

A

The phenotypes they produce

128
Q

Natural selection acts upon _________.

A

existing variation

129
Q

New traits evolve from ________.

A

ancestral traits

130
Q

If mutation is favorable by chance, it may _____ the population due to ______________.

A

increase, increased fitness of the organism

131
Q

Does assortative mating influence genotype frequency or allele frequency?

A

genotype frequency

Bio 150 (5 decks)

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