Final Exam/ Quizzes

Question 1

A 9-year-old child presents with puffy eyelids early in the morning and smoky urine. Her Anti-Nuclear Antibody and anti-double stranded DNA antibody tests are negative, but the Anti-Streptolysin O antibody titer is elevated. Which type of hypersensitivity reaction is this?

Answer 1

III

Question 2

Which of the following cells are involved in both cell-mediated and humoral immunity?

Answer 2

Macrophages

Question 3

What is the role of dendritic cells in the immune system?

Answer 3

Presenting antigens to Tcells

Question 4

Which is the HLA genetic marker for psoriatic arthritis?

Answer 4

B27

Question 5

Which immunoglobulin is first produced in response to an antigen?

Answer 5

IgM

Question 6

In which organ are histiocytes found?

Answer 6

Skin

Question 7

Which cells are derived from B cells?

Answer 7

plasma cells

Question 8

Which of the following is an example of innate (non-specific) immunity?

Answer 8

Neutrophils phagocytes

Question 9

Which disease is caused by a Type II hypersensitivity reaction?

Answer 9

Rhesus incompatibility

Question 10

Which autoimmune disease is characterized by dry eyes, xerostomia and anti-SSA/SSB antibodies?

Answer 10

Sjogren’s syndrome

Question 11

Which is part of the CREST syndrome?

Answer 11

Sclerodactyly

Question 12

Systemic Lupus Erythematosus is more likely to be associated with which condition?

Answer 12

Limban-Sacks endocarditis

Question 13

A 20-year-old African American complains of swollen painful fingers and wrists. She has a low-grade fever and a malar rash. Her anti-double stranded DNA antibody titer is very high. Which type of hypersensitivity reaction is the primary cause of the joint pains and rash seen in this patient?

Answer 13

III

Question 14

A 45-year-old female with Raynaud’s phenomenon develops dysphagia. On examination her face shows numerous telangiectasia. Which antibodies to which are most likley to be present in this patient?

Answer 14

centromeric proteins

Question 15

A HIV-positive intravenous drug user is suspected of having tuberculosis and a Mantoux test is done. There is a 10 cm area of induration 48 hours after the test was administered. Which are involved in this type of hypersensitivity reaction?

Answer 15

T cells and macrophages

Question 16

Which organ transplant rejection type occurs within minutes to hours and involves preformed antibodies?

Answer 16

hyperacute

Question 17

Chronic rejection of a transplanted organ is characterized by immediate thrombosis of major vessels and death of donor tissue cells

Answer 17

False

Question 18

A 24-year-old woman develops an acute allergic reaction 10 minutes after receiving a blood transfusion during surgery. Which immunoglobulin in her body reacted to the donor’s antigens?

Answer 18

G

Question 19

Which is characteristic of Bruton’s agammaglobulinemia?

Answer 19

absent germinal centers in the lymph nodes

Question 20

What is the primary cause of acquired immune deficiency syndrome (AIDS)?

Answer 20

infection with the human immunodefiency virus (HIV)

Question 21

Which phase of HIV infection is characterized by persistent generalized lymphadenopathy?

Answer 21

III

Question 22

The final phase of AIDS is characterized by a CD4 count below 200 cells per cubic millimeter and the development of AIDS-defining illnesses. T or F

Answer 22

True

Question 23

DeGeorge syndrome is associated with a deletion on chromosome 22 and affects T-cell development due to thymic aplasia. T or F

Answer 23

True

Question 24

AIDS is associated with lymphocytosis. T or F

Answer 24

False

Question 25

Which test for HIV infection has the highest specificity and therefore is used to confirm the infection?

Answer 25

western blot

Question 26

A deficiency of which nutrients is seen in an infant who is emaciated, with a cachectic appearance and does not have subcutaneous fat?

Answer 26

All macronutrients

Question 27

What is the characteristic feature of Kwashiorkor?

Answer 27

edema

Question 28

Which fat-soluble vitamin deficiency causes nyctalopia and Bitot's spots?

Answer 28

A

Question 29

Which disease is associated with radiographic features such as metaphyseal splaying and cupping?

Answer 29

Ricket's

Question 30

Which presentation is indicative of a lack of vitamin K?

Answer 30

Excessive bleeding from the umbilicus in the newborn

Question 31

Which is associated with thiamine deficiency?

Answer 31

chronic alcoholism

Question 32

Which finding is seen in wet beriberi?

Answer 32

tachycardia

Question 33

Which symptom is associated with vitamin B2 deficiency?

Answer 33

Angular cheilosis

Question 34

Which vitamin is deficient in a person who presents with dementia, diarrhea and dermatitis pattern called Casal's necklace?

Answer 34

niacin

Question 35

Which vitamin is deficient in Pellagra?

Answer 35

B3

Question 36

Which deficiency will result in neural tube defects?

Answer 36

folic acid

Question 37

All of the following are causes of a vitamin B12 deficiency EXCEPT?

Answer 37

diet deficient in citrus fruit

Question 38

Which vitamin deficiency is associated with spastic paralysis and sensory ataxia?

Answer 38

B12

Question 39

Loss of the ability of the body to hydroxylate proline and lysine in the formation of collagen will result in which disease?

Answer 39

scurvy

Question 40

Which mineral deficiency leads to microcytic hypochromic anemia?

Answer 40

iron

Question 41

What is the most reliable test for iron deficiency?

Answer 41

ferritin

Question 42

Which could result from a diet deficient in iodine in an adult?

Answer 42

myxedema

Question 43

Where are Kayser-Fleischer rings found?

Answer 43

around the cornea

Question 44

Which mineral excess is associated with bronze diabetes?

Answer 44

iron

Question 45

Which is a feature of plumbism?

Answer 45

blue gum line

Question 46

Minimata disease is associated with excess of which mineral?

Answer 46

mercury

Question 47

Which BMI range is considered Class I obesity?

Answer 47

30-34.9

Question 48

Which condition is associated with excess consumption of alcohol?

Answer 48

wernicke-korsakoff psychosis

Question 49

What is the cause a patient's symptoms of carbon monoxide poisoning?

Answer 49

severe hypoxia

Question 50

What is usually the cause of hypervitaminosis E?

Answer 50

chronic over supplementation