Final exam up till radiation Flashcards

1
Q

what is BCF

A

the tendency for a substance in water to accumulate in organisms

When exposed for a long enough period of time eq will be reached
lab baised

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2
Q

How do you determine BCF

A

Internal concentration / external concentration

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3
Q

what is BAF

A

provides a ratio between the chemical conc in an envoirnment and what is found within the wildlife
feild baised

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4
Q

what is biomagnification

A

increases in conctrations of substances as you move up the food chain

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5
Q

how does bioacculmation differ in contaminates that are readily water soluble rather that lipophilic compounds

A

they undergo carrier mediated uptake bc they cannot readily diffuse across the lipid bilayer

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6
Q

how does BCF charts correlate to accumulation

A

the stepper the chart the more the substance accumulates

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7
Q

why is bioaccumulation so important

A

bc if a compound is found to have a high BCF then low concretions in the environment can result in high concretions in the host tissue

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8
Q

what makes a substance toxic under CEPA guidlines

A

Have a harmful effect on the environment or its biological diversity

may cause danger to envvoinment on which life depends

may cause danger to human health or death

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9
Q

what is the Octanol-water Partition Coefficient

A

measurement of lipophilicity and hydrophobicity which can be determined by dissolving octanol and water into a flask along with a orgnic soild, after which mesuring the conc of the organic soild in both the liquids to determine which has accumulated more, a low value means greater hydraulicity

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10
Q

what is the realtionship between BCF and high Octanol-Water Partition

A

the BCF will be high if the Octanol water partition is high, this is bc lipophillic substances tend to accumlate in greater conctrations in tissue

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11
Q

what is the priority substances list

A

contains substances which are to be assessed to determine if they pose a health risk to humans

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12
Q

Organophosphate insecticiides

A

AChE breaks down acetylcholine which is a neurotransmitter which can buildup at nerve ending effecting neural implusise

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13
Q

what is normalization

A

means adjusting values measured on different scales to notionally common scale for comparsion

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14
Q

what is the toxic model approach

A

ratio concentration to defined endpoint

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15
Q

how to calculate toxic unit approach

A

find the toxic units for both contaimates

A= concA/LC50A
B= conc B/ LC50B

toxicity is then the meaure of tuA+tuB
LC50 is reached when sum of TU is = 1

however this can only be applied is addivtive sitiutations

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16
Q

what are the 2 main types of radaition

A

non-ionizing which is safer to us

ionizing which is much less safe and has mutagentic effects

17
Q

what kind of particles produce ionizing radiation

A

x-ray and gamma ray

18
Q

what kind of praticles produce nonionizing radation

A

Sound, electric, radio

19
Q

what are some factors which make radiation dangerous

A

Penetration and ionization

20
Q

what the 2 majour ways in which radation can infience damage on our cells

A

Mutagenic- tagrets genes
Cacinogenic- causes cancer

21
Q

differentiate between alpha beta and gamma radiation

A

alpha- 2 protons and 2 neutrons which has a low penetraticng ability but interacts strongly with matter

Beta- neg eletronsg which morderate penitatration

Gamma- no mass, huge penitration ability

22
Q

what are free radicals

A

An atom of moleucle w a unpaired electron in outer shell making it very reactive, this can reslut from radiation.

23
Q
A