pesticides Flashcards
some general charateristccs on Organochlorine insecticides
Degrades slowly, lipid soluble
high bioaccumulationa and magification
what determines the toxicity in Dioxins
The number of Cl as well as there location on the benzene rings
what is a Congener
One of many variants of configurations of a common chemical structure
what is the TEQ system
International Toxic Equivalents
a summation of the potential toxicity of each congener
what are POPs
Persistent organic pollutants
charteristics of POPs
Resistnt to envoironmental degradation through chemical, biological and photolytic porcesses
They persist and are capable of long range transport
Bioaccumulat ein tissue and biomagify in food chains
Potential for significant impacts on humans health and environment
GABAA receptor
At sunapse of neuron which allows for confomational changes which allows for Cl to rush into neuron , effecting this receptor causes hyper excitatory reponses
Prganophospahse insecticides
Are more toxic to mammals
Degrade faster than organochlorines
Lipid souble so they bioaccumulate
Mode of action is inhibtion of acetylchloine esterase
inhibtion of AChE
Done by Organophosphate insecticides which inhibit GABBAA recepor which leads to hyperstimulation of cholinergic pathways
Carbamate insecticides
Degreades rapidly
some human effecst
inhibits acetlycholone esterase
PMRA
pesiticde regulation in canada
Noe-nucotunoid insecticides
Neuroactive which is effective at low doses
Developed bc of there reduced toxicity to mammals (selctive to insects)
what is the most widly used herbicide
Atrazine
what are PPCPs
Pharmaceuticals and personal care products which can leak into drinking water
what is a Pseufo persistent substance
one which break down in the voirnment w a short halflife however they are contantly realsed into the ecosystem therefore it appreas as if they are highly persistant
