Final Final Final Stuff Flashcards

(58 cards)

1
Q

spermatogenisis

A

forms 4 haploid sperm cells

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2
Q

oogenisis

A

haploid egg and polar bodies

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3
Q

fertilization step

A

egg is not accessible

sperm releases acrosome to dissolve top layer

sperm actin binds to egg and penetrates inside to cytoplasm

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4
Q

development is characterized by ______

A

coordinated change

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5
Q

coordinated changes during development

A

change in size
change in biochemistry and physiology
change in form and functionality

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6
Q

developmental periods

A

cleavage (fertilization)
Patterning (germ layers)
Differentiation (special tissue)
Fetal Growth (get big)

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7
Q

describe the cleavage phase

A

zygote to blastocyst

trophoblast forms outside and inner cell mass the inside

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8
Q

what are the two layers of the trophoblast?

A

cytytrophoblast (inner)
Synciotrophoblast (outer)

together they form the placenta

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9
Q

gastrulation phase

A

formation of germ layers from primitive streakq

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10
Q

ectoderm

A

skin, cns, pigment

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11
Q

mesoderm

A

heart, muslce, kidney, rbc, smooth muscle, digestive

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12
Q

endoderm

A

lungs, thyroid, pancreas

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13
Q

neurulation

A

notochord forms in mesoderm, tells ectoderm to form neural tube (CNS)

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14
Q

organogenisis

A

follows gastrulation and folding, limbs take shape

most systems have developed by week 8

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15
Q

fetal period (9-38 weeks)

A

growth. Premature birht before 38 weeks, can live 30 weeks without help and 22 can survive with it

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16
Q

neural crest cells

A

surround the neural tube and become

neurons, ganglia, cartilage, bone, connective tissue, adrenal cells, neurons, glia, pigment cells

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17
Q

DDT

A

male reproductive disorders

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18
Q

male disorders

A

low sperm counts, testicular cancer, undescended testes, male breast cancer

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19
Q

hypospadius

A

urethra out the bottom

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20
Q

epispadius

A

urethra out the top

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21
Q

where can you find ribosomes?

A

rough ER, nucleus, free floating

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22
Q

cystic fibrosis

A

CFTR sequence has deleted Phe leading to mutation of chloride channel which causes chlorine to stay in the cell and mucous builds on the outside. Protection against cholera

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23
Q

kinetic energy types

A

thermal, electromagnetic, electrical

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24
Q

potential enrgy types

A

chemical, mechanical, nuclear, gravitational

25
how and where does glycerol enter glycolysis?
as DHAP, forms 1 NADH before entering. Requires 1 ATP
26
b oxidation occurs in the
mitochondrial matrix
27
fascilitated diffusion
carrier mediated passive transport
28
primary active transport
uses ATP to pump against gradient
29
secondary active transport
couples the movement of an ion down its concentration gradient with the movement of another molecule against its concentration gradient
30
characteristics of carrier mediated transport
specificity, saturation, competition
31
glucose transporters 1-4
1: basal uptake and high affinity 2: low affinity, glucose sensing 3. Basal uputake and high affinity 4. Dynamic at the membrane
32
Paracrine/ Autocrine signaling
communication with neighboring cells through increased concentration gradient of messenger
33
juxtacrine signaling
non-secretion, cell to cell signaling
34
VX gas
inhibits acetylcholinesterase
35
cholera toxin
stim formation of cAMP which opens CL channels in intestine, activates nA pump. Leads to crazy diahrea.
36
resting membrane potential, K, NA
-70, -96, +62
37
lidocaine
blocks sodium voltage gated channels so action potentials can't be generated
38
absolute refractory period
dudring depolarization, can't generate another action potential
39
relative refractory period
repolarization and hyperoplarization, AP can be generated but only with a larger than normal stimulus
40
contiguous conductino
unmylenated action potential propogation
41
saltatory conduction
mylenated, channels concentrated at nodes
42
Multiple Sclerosis
autoimmune attack of myelin, degeneration of axons. Tingling, numbness, balance and coordination probems
43
threshold
-55 mv, NA close and K open at 30
44
EPSP
excitatory post synaptic potentail (NA in, K out)
45
IPSP
inhibitory post synaptic potential (K out)
46
Temporal summation
adding epsps and ipsps from same presynaptic neuron at high frequency
47
spatial summation
adding epsps and ipsps from 2 presynaptic neurons onto 1 post synaptic neuron
48
precinaptic facilitaiton/inhibition
one presynapic neuron acts on another to release more or less neurotransmitter onto post synaptic neuron
49
GPSP
combo of all e/ipsps on post synaptic neuron at the same time. WIll it fire?
50
interneurons found in
CNS
51
Astrocytes
most abundant glial cell, maintain structure and order of brain surround cleft and gontaine glutamate transporters to remove it after exocytosis provide neurons with nutrients, regulate bloodflow, form BBbarrier
52
high synaptic GLU
damage to cytoskeleton, membrane, and dna. Happens with brain injury, hearing loss, alzheimer,s parkinsons, huntingtons
53
oligodendrocytes
make myelin in CNS, up to 50 neurons
54
schwann cells
make myelin in PNS, up to 1 neuron
55
microglia
immune cells of CNS, phagocytosis
56
ependymal cells
form epithelium, secrete CSF, contain cilia for CSF movement, stem cell qualities
57
post concussion
low frontal lobe function
58
meninges (inside out)
PAD