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1

What is the status of the
Nucleic Acid
Polymerase
and reason why in

picornavirus, norwalk, corona, togavirus, flavivirus

plus-stranded RNA
no pol
virion RNA serves as mRNA to make the polymerase in infected cells

Note:
pico (non-enveloped)
Norwalk (non-enveloped)
Corona (enveloped)
Flavi and Toga (enveloped)

2

What is the status of the
Nucleic Acid
Polymerase
and reason why in

orthomyxovirus

segmented minus-stranded RNA
RNA-dependent- RNA polymerase
virion RNA cannot serve as mRNA

enveloped

3

What is the status of the
Nucleic Acid
Polymerase
and reason why in

reovirus

segmented double-stranded RNA
RNA-dependent- RNA polymerase
virion RNA cannot serve as mRNA

non-enveloped

4

What is the status of the
Nucleic Acid
Polymerase
and reason why in

retrovirus

two identical +single-stranded RNA
RNA-dependent DNA polymerase (reverse trans- criptase)
to make a DNA transcript of virion RNA

Enveloped

5

What is the status of the
Nucleic Acid
Polymerase
and reason why in
adenovirus
herpes virus

linear double- stranded DNA
no pol
uses host enzyme to make mRNA

adeno is non-enveloped
herpes is enveloped

6

What is the status of the
Nucleic Acid
Polymerase
and reason why in

poxvirus

linear double- stranded DNA
DNA-dependent- RNA polymerase
cannot use host cell mRNA synthesizing enzymes because it replicates in the cyto- plasm
Pox: non-enveloped and enveloped

7

What is the status of the
Nucleic Acid
Polymerase
and reason why in

hepatitis B virus

circular double- stranded DNA with some single- stranded patches
reverse tran- scriptase (generally misnamed "DNA polymerase")
must insert into host DNA
Enveloped

8

What is the status of the
Nucleic Acid
Polymerase
and reason why in

parvovirus

single-stranded DNA
No pol
uses host enzymes
to make single- stranded genome into double-stranded DNA and to make mRNA
Non-enveloped

9

What are the viruses with a
Respiratory route of infection?

rhinoviruses (often finger-to-nose)
influenza viruses
parainfluenza viruses
mumps virus
measles virus
rubella virus
varicella-zoster virus
smallpox virus
adenovirus
parvovirus B-19

10

What are the viruses with GI route of infection?

polioviruses
Coxsackie viruses
ECHO viruses
hepatitis A virus
hepatitis E virus
Enteric adenovirus
Norwalk virus
rotaviruses that cause diarrhea in infants enteric adenoviruses

11

What are the virus with skin contact route of infection?

papilloma viruses that cause cutaneous warts
herpes simplex virus type 1 molluscum contagiousum virus

12

What are the virus with venereal route of infection?

hepatitis B virus
hepatitis C virus (probably)
hepatitis D virus
herpes simplex virus type 2
HIV -1
papilloma viruses that cause genital warts
(at least you got something out of it)

13

What are viruses with transplacental route of infection?

rubella virus
cytomegalovirus
HIV -1
parvovirus B-19
varicella-zoster virus
lymphocytic choriomeningitis virus (LCMV)

14

What are viruses with perinatal route of infection?

herpes simplex
hepatitis B virus
hepatitis C virus (probably) hepatitis D virus
HIV -1

15

What are viruses with breast milk route of infection?

HIV cytomegalovirus

16

What are viruses with arthropod bite route of infection?

arboviruses

17

What are viruses with blood exchange route of infection?

hepatitis B virus
hepatitis C virus
hepatitis D virus
HIV -1

18

What are viruses with animal bite route of infection?

Rabies virus

19

What is the vaccine type for Measles?

Live-attenuated

20

What is the vaccine type for mumps?

Live-attenuated

21

What is the vaccine type for rubella?

Live-attenuated

22

What is the vaccine type for rotavirus?

Live-attenuated oral

23

What is the vaccine type for small pox?

live-attenuated

24

What is the vaccine type for varicella-zoster?

live-attenuated

25

What is the vaccine type for yellow fever?

live attenuated 17-D

26

What are the vaccine types for polio?

Live-attenuated and killed vaccines
killed (Salk)
Live attenuated (Sabin)
Live not used in U.S.

27

What are the vaccine types for influenza?

Killed (all ages)
live-attenuated (intranasal 2-49 year olds)

28

What is the vaccine type for Hep A?

Killed

29

What is the vaccine type for Hep B?

Killed
(a viral protein produced in yeast by genetic engineering (subunit vaccine). The older killed vaccine made from HBAg in human
serum has been largely replaced by
the subunit vaccine.

30

What is the vaccine type for HPV?

killed