Final Review - EXAM 1

Question 1

what term best represents the future of biomaterials science

Answer 1

regeneration

Question 2

what type of intermolecular force helps cause cohesion of water

Answer 2

hydrogen bonding

Question 3

the last 20 years have seen a ___ in the use of bioactive materials in medical applications

Answer 3

increase

Question 4

what results in the highest contact angle regarding polar/nonpolar surfaces and liquids

Answer 4

polar surface, non-polar liquid

Question 5

work of adhesion is ___ to the contact angle

Answer 5

inverse/opposite

Question 6

stronger bond forces make surface free energy ___

Answer 6

larger

Question 7

draw a water droplet on a surface with young’s equation

Answer 7

ysv = ysl + ylv cos (theta)

Question 8

what is the dupre equation?
what is the work of adhesion equation when youngs equation is plugged in?

Answer 8

1. Wa = ysv + ylv - ysl
2. ylv(1+cos(theta))

Question 9

if a material has a high work of adhesion, it has a ____ surface free energy

Answer 9

higher

Question 10

the work of adhesion of teflon is

Answer 10

very low

Question 11

ESCA stands for

Answer 11

electron spectroscopy for chemical analysis

Question 12

XPS stands for

Answer 12

x-ray photoelectron spectroscopy

Question 13

what information can be derived from XPS

Answer 13

atomic composition and bonding information

Question 14

advantages of XPS

Answer 14

surface sensitive - scanns 8-10 nm from surface
non-destreuctive
able to analyze wide range of samples without specialized preparation

Question 15

challenges of XPS

Answer 15

expensive equipment, expert operator, vulnerable to contamination

Question 16

mechanism of XPS

Answer 16

photoelectric effect - emission of electrons when electromagnetic energy strikes a material
BE = hv - KE

Question 17

SEM stands for

Answer 17

scanning electron microscopy

Question 18

___ is the smallest discernable feature

Answer 18

resolution

Question 19

SEM offers a ____ depth of field compared to light microscopy

Answer 19

greater

Question 20

Sketch and explain AFM imaging

Answer 20

drawing

Question 21

SEM uses a ______ electron beam

Answer 21

high energy

Question 22

Secondary electron microscopy

Answer 22

uses secondary electrons to obtain a high spatial resolution

Question 23

backscatter electron imaging

Answer 23

electrons reflect back to create higher contrast image

Question 24

energy dispersive x-ray (EDS)

Answer 24

core electrons are displaced, allowing us to identify chemical composition

Question 25

surface modification with silane chemistry is based off of

Answer 25

covalent bonding

Question 26

surface modification with self assembeled monolayers is based off of

Answer 26

non-covalent affinity between thiols and gold

Question 27

ECM is composed of

Answer 27

proteins (collagen) and polysaccarides

Question 28

integrins are an example of a

Answer 28

receptor

Question 29

will surface modication have an effect on the mechanical properties of the materials?

Answer 29

no

Question 30

layer-by-layer films are stabilzed by

Answer 30

electrostatic interactions

Question 31

how are polyelectrolytes created

Answer 31

a charged macromolecule is dipped into a polycatonic or polyanonic solution which builds its layers

Question 32

sketch nimpam modified surface below and above the LCST

Answer 32

drawing

Question 33

plasma is made from

Answer 33

gas

Question 34

integrin contains

Answer 34

RGD sequences which allow for amino acid binding

Question 35

treating a material with plasma will

Answer 35

increase wettability

Question 36

why does TCPS allow for better cell adhesion

Answer 36

casued by a change in surface chemistry

Question 37

TCPS uses a ____ type of plasma treatment

Answer 37

RFGD plasma treatment

Question 38

sketch free radical polymerization steps

Answer 38

drawing

Question 39

an amphiphillic molecule is

Answer 39

hydrophillic and hydrophobic ex: phospholipids

Question 40

protein adsorption is _____ because

Answer 40

spontaneous because of increased entropy from the change of waters ordered confirmation which increases randomness (entropy)

Question 41

do proteins adsorbed to non-polar surfaces expirence changes in confirmation?

Answer 41

yes

Question 42

why is adsorption of proteins favored over adsorption of a single amino acid

Answer 42

adsorption of proteins allows for more hydrogen bonds which is energetically favored

Question 43

adsorption to charged surfaces involve/require

Answer 43

a cation and an anion

Question 44

the vroman effect describes

Answer 44

that the adsorbed protein layer changes over time