FINAL: Skeletal System Function & Histology Flashcards

(38 cards)

1
Q

What is the skeletal system

A

A dynamic system of connective tissue
Balance between production and remodeling

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2
Q

What are the functions of bones

A

Support
Protection
Movement
Electrolytes and Acid/Base balance
Blood cell differentiation (Hematopoiesis)

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3
Q

How many bones are humans born with

A

Over 300

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4
Q

How many bones do adults have

A

206

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5
Q

Sesamoid bone

A

Small bones
Embedded within tendon where is passes over a joint
Ex: patella

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6
Q

Wormian bones

A

Extra irregularly shaped bone pieces that occur within a suture in the cranium

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7
Q

What part of the long bone is this

A

Diaphysis (shaft)

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8
Q

What part of the long bone is this

A

Epiphysis (end of long bone)
Top - proximal epiphysis
Bottom - distal epiphysis

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9
Q

What part of the long bone is this

A

Metaphysis (growth plate region)

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10
Q

What part of the long bone is this

A

Medullary cavity (filled with yellow bone marrow)

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11
Q

What part of the long bone is this

A

Endosteum (inside)
- connective tissue lining medullary cavity
- contains osteogenic (bone-forming) cells

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12
Q

What part of the long bone is this

A

Periosteum (outside)
- connective tissue covering bone but not the cartilage
- osteogenic (bone-forming) cells and blood vessels that nourish or help with repairs

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13
Q

What part of the long bone is this

A

Articular cartilage
- covers joint to reduce friction & absorb shock

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14
Q

What are the two types of bone marrow

A

Red marrow and yellow marrow

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15
Q

What is red marrow

A

Found at epiphysis of long bones & spongy bone
Site for hematopoiesis (blood cell formation)

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16
Q

What is yellow marrow

A

Found within the medullary cavity
Stores fat

17
Q

What are the types of tissue that bones are composed of

A

Cartilage
Osseous tissue
Epithelium
Nerve
Blood forming tissue
Adipose
Dense connective tissue

18
Q

What is osseous tissue

A

Connective tissue normally called “bone”

19
Q

What are the 3 basic components of connective tissue

A

Cells
Fibers
Ground substance

20
Q

What makes up the matrix of connective tissue

A

50% ground substance
25% collagen fibers
25% water

21
Q

What does osseous tissue consist of

A

Bone cells with a mineralized matrix

22
Q

What are osteoprogenitor (osteogenic) cells

A
  • stem cells
  • divide to replace themselves or to produce osteoblasts and osteocytes
  • found in periosteum, endosteum
23
Q

What are osteoblasts

A
  • secrete unmineralized bone matrix (osteoid)
  • some mature into osteocytes
24
Q

What are osteoids

A

Collagen, calcium-binding proteins

25
What are osteocytes
- mature bone cells - help maintain surrounding matrix - act as stress or strain sensors - communicate with other bone cells to regulate bone growth and resorption
26
What are osteoclasts
- cells of matrix destruction - derived from the same stem cells that become white blood cells - large, multinucleate cells - responsible for bone resporption (destruction)
27
What does the osteon consist of
Concentric layers of bone matrix called lamellae surrounding a central canal (Haversian canal)
28
What is the red arrow pointing to
The volkmann’s canal - how Haversian canals are connected - network of blood vessels
29
Where are osteocytes located
Small pockets called lacunae
30
What are the small channels that allow osteocytes to communicate with one another and receive nutrients
Canaliculi
31
What is this red line pointing to on the osteon
Canaliculi
32
What is this component of an osteon
Lamallae
33
What is this component of an osteon
Haversian canal
34
What is this component of an osteon
Lacunae with osteocytes inside
35
What is the purpose of the harness of the matrix
To provide resistance to diffusion
36
What happens to osteoblasts producing osteoid/matrix
They become trapped and differentiate into osteocytes
37
Are there osteon in spongy bone
No true osteons in spongy bone
38
What is this part of spongy bone
Trabeculae