Flashcard 3

1
Q

sporadic disease

A

occurs only occasionally or in a few isolated places

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2
Q

Gonad

A

organ that produces gametes

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3
Q

only hormone to decrease [BG]

A

insulin

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4
Q

autocrine

A

cells secrete chemicals that bind to receptors on that same cell

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5
Q

what stimulates cartilage deposition by chondrocytes when they become calcified

A

IGF- 1

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6
Q

mode of action vasopressin in vascular smooth muscle

A

contracts to increase blood pressure

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7
Q

what is an arteriole lining made of

A

several endothelial cells

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8
Q

paracrine

A

chemicals diffuse to affect neighbouring cells

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9
Q

what 3 factors does development of diabetes type 1 require

A
  • genetic predispostion
  • trigger
  • autoimmunity
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10
Q

what produces glucagon

A

alpha islets of langerhans

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11
Q

where are TAGs stored

A

liver and adipose tissue

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12
Q

what is somatostatin main pancreatic action and what is the purpose of it?

A

inhibits GI tract activity, slowing down absorption of nutrients and preventing exaggerated peaks in plasma conc

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13
Q

what happens when free hormones leave the plasma

A

more hormone is released by the carrier proteins

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14
Q

thyroid hormone solubility in plasma?

A

poor

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15
Q

processes that occur when there is more insulin than glucagon

A
  1. gluconeogenesis
  2. glycogenolysis
  3. ketogenesis
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16
Q

primary purpose glucagon

A

raise [BG]

17
Q

what can cause peripheral insulin resistance

A

abnormal response of insulin receptors in these tissues/ a decrease in their numbers

18
Q

hypoglycaemia

A

[BG] <3mmol/l

19
Q

when is the majority of GH released?

A

delta sleep

20
Q

osteocytes

A

regulate the activity of osteoclasts and osteoblasts

21
Q

what is a growth hormone?

A

peptide hormone released by anterior pituitary e.g. somatotropin

22
Q

hirtuism

A

excessive body hair in men and women on parts of the body where hair is normally absent