Fluids and Electrolytes Flashcards

1
Q

We are ____ % water.

_____ intracellular and _____extracellular.

A

60%

2/3 and 1/3

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2
Q

________ fluid composition is 80% _____ and 20% _____.

A

Extracellular

interstitial fluid

plasma

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3
Q

When managing patient’s fluid status, consider: (4)

A
  • NPO deficit
  • maintenance
  • evaporative losses and “third spacing”
  • blood loss
    *
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4
Q

Do not give too much fluid to what patients? (2)

A
  • renal
  • CHF (increases preload, which increases contractility, causing cardiogenic pulmonary edema)
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5
Q

Hourly maintenance calculation:

A

4-2-1 rule

or add 40 if weight greater than or equal to 20 kg

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6
Q

4-2-1 Rule

Add 4ml/kg/hr for first ___kg

Add 2 ml/kg/hr for second ___kg

Add 1 ml/kg/hr for all weight in excess of 20 kg!

A

10

10

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7
Q

When a wound is large, or when a highly vascular mucosa is exposed during surgery (GI tract or lungs), _____ ___ can be significant.

Minimal tissue trauma (herniorraphy): ___ - ___ ml/kg/hr

Moderate (cholecystectomy): ___-___ ml/kg/hr

Severe (bowel resection): ___-___ ml/kg/hr

A
  • evaporative losses
  • 2-4
  • 4-6
  • 6-8
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8
Q

This refers to an internal redistribution of fluids, especially during large thoracic or abdominal procedures.

_______ ____ volume is depleted as inflamed tissue sequesters much fluid in the interstitial space. Replacement of this fluid is necessary to avoid organ hypoperfusion, especially in renal insufficiency.

A

Third spacing

Intravascular fluid

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9
Q

Small lap pads can hold ___ ml of blood.

Large lap pads can hold ____ ml.

A

10 - 15ml

100 ml

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10
Q

Only ___ of the crystalloid will remain in the plasma.

It follows the distribution of ______ _____, most of it passing to the ____ _____.

It cannot pass intracellularly (into the cell) because ions do not cross cell membranes.

A
  • 1/3
  • extracellular water
  • interstitial fluid/tissue
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11
Q

______ are solutions of inorganic and small organic molecules dissolved in water.

The main solute is saline or glucose and the solution may be iso, hypo, or hypertonic.

A

Crystalloid

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12
Q

The following are advantages of_______:

safe, nontoxic, reaction free, and cheap

A

crystalloid

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13
Q

Disadvantages of crystalloid: (2)

A
  • limited time in IV space
  • edema with large volumes
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14
Q

Half life of crystalloids in IV space is:

A

30 - 60 minutes

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15
Q

In a balanced salt solution of 1000 ml,

  • ____ ml will redistribute to the intracellular space
  • ___ ml will redistribute into the extracellular space

In extracellular space, ____ will remain intravascular space.

A

0 ml

1000ml

1/4

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16
Q

Normal saline (0.9%) is:

considered ______

_____ mOsm

A

acidic, pH is 5.5

308 mOsm

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17
Q

Lactated Ringers contains what? (5)

A
  • Na
  • Cl
  • K
  • Ca
  • Lactate
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18
Q

Lactated Ringers

  • Acidity is ____
  • _____ mOsm
A

low, pH is 6.5

273

19
Q

Plasma-Lyte components:(4)

A
  • Na
  • Cl
  • K
  • Mg
20
Q

Plasma-Lyte pH is _____.

21
Q

Saline solution can cause _____ ____ ____.

A

hyperchloremic metabolic acidosis

22
Q

Lactated Ringers can cause _____ _____

A

metabolic alkalosis (lactate –> HCO3)

23
Q

Be careful with________containing solutions for renal and hyperkalemic patients.

24
Q

Use ____ in neuro cases because it is _____-osmolar and improves the visual field.

A

Normal saline

hyper

25
The \_\_\_\_\_ in LR prohibits its use in the presence of blood transfusions.
Calcium
26
Homogeneous noncrystalline substance consisting of large molecules dissolved in a solute. Most are dissolved in normal saline, but glucose, hypertonic saline, and LR have been used as well.
Colloid
27
Advantages of colloid: (3)
* Greater capacity to remain in the IV space (longer half life) * more efficient for replacing a severe fluid deficit quickly * smaller infused volume
28
Disadvantages of colloid: (3)
* Greater expense * coagulopathy * hypersensitivity reactions
29
Hextend is hetastarch in \_\_\_\_\_. Hespan is hetastarch in \_\_\_\_.
LR NS
30
If we have lost over ___ of the ABL (acceptable blood loss) replace with colloid, especially if the patient is starting to show hemodynamic changes.
1/3
31
What colloid has the longest half life? However, it can impair ____ function.
Hetastarch platelet
32
\_\_\_\_\_\_ \_\_improves microcirculation blood flow by decreasing blood viscosity and is often used by vascular and plastic surgeons to maintain patency of anastamoses.
Dextran 40
33
Dextran (mostly \_\_\_), also known as \_\_\_\_\_decreases platelet aggregation and adhesiveness. ## Footnote
70 Hetastarch
34
Distribution of 1000ml 5% colloid: \_\_\_ml in intracellular water \_\_\_\_\_ml in extracellular water Of the extracellular water, \_\_\_ ml in extravascular water \_\_\_ ml in intravascular water
0 1000 0 1000
35
Know normal lab values: * Na * K * Ca * Mg * Cl * HCO3 * PO4 * SO4
36
\_\_\_ and water flow together and is the key regulator of water balance in the body. Its measured value represents ___ rather than total body sodium. Sodium is the most abundant cation of the ___ \_\_\_\_and is critical in determining the ____ and ____ osmolarity.
* Na * TBW (total body weight) * extracellular fluid * extracellular * intracellular
37
Hyponatremia occurs when plasma Na \< ___ mEq/L Causes: (3)
135 True loss of sodium (sweating, vomiting, diarrhea, burns, and the administration of diuretics) _Dilutional Hyponatremia_: Due to an excess of TBW. This is the most common cause of hyponatremia and is not a deficiency of total body sodium!! Causes of excess TBW= excess ADH release (stress, SNS activation, SIADH),TURP syndrome.
38
What percent of D5W will go: intracellularly/extracellularly? extravascularly/intravascularly?
2/3 intracellularly, 1/3 extracellularly only 25% will of extracellular will remain in intravascular space
39
No _____ substance crosses into the intracellular space due to the lipophilic cell membrane (unless cotransported).
ionized
40
Hypotonic fluids can promote hyponatremia and have a _______ intravascular half life.
shorter
41
\_\_\_\_\_ can lead to a reduction in factor VIII and vWf, impairs plt function, and can prolong PTT.
Hetastarch
42
This fluid's side effects include hypocalcemia allergic reactions \< 1% and impaired lung function.
albumin
43
This fluid's side effects include hypotension (common) and allergic reaction.
plasma protein fraction
44
KEY TERM What EKG change would you observe in a hypocalcemic patient? (2)
long QT interval changes heart block