focused clinical history taking and examination - rheumatology Flashcards

(28 cards)

1
Q

What is the function of synovium

A

Maintenence of intact tissue

lubrication of cartilage

control of synovial volume

Nutrition of the chondrocytes within the joints

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2
Q

What happens to the joints in osteoarthritis

A

the cartilage surface becomes rough

synovium is mildly thicker then usual

bone deformities can occur

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3
Q

What happens to the joint in rheumatoid arthritis

A

The synovial lining becomes thickened due to inflammation

The cartilage becomes thinner

More synovial fluid production due to the thickened synovium

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4
Q

What age group is osteoarthritis more common in

A

over 50 years old

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5
Q

What is a likely cause of mechanical pain at a joint in a younger person

A

hypermobility

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6
Q

Which joints does osteoarthritis most commonly affect

A

1st carpo-metacarpal/ distal interphalangeal and proximal interphalangeal (thumb side)

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7
Q

which joints does rhematoid arthritis more commonly occur

A

MCPs/ PIPs

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8
Q

Where does pseudogout most commonly occur

A

Wrist or knee in the elderly

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9
Q

Where does spondyloarthritis more commonly occur

A

Monoarthritis in the young

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10
Q

Where does gout most commonly occur

A

1st MTP/ankle/knee/elbow

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11
Q

What is early morning stiffness over 30 minutes a sign of

A

Inflammatory arthritis

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12
Q

what is characteristic of inflammatory pain

A

Worse on rest but better with movement

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13
Q

What characterises mechanical pain

A

Worse on movement, better on rest

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14
Q

Which diseases are constitutional symptoms more common in - malaise, fatigue and weight loss

A

Inflammatory arthritis and rare rheumatic diseases such as lupus

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15
Q

What rashes should be looked for in MSK exam

A

psoriasis
erythema nodosum
photosensitive
vasculitic

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16
Q

Where are the common enthesitic points

A

Epicondylitis/achilles and heel

17
Q

If the joint is bony or hard, what is the suggestive diagnosis

A

osteoarthritis

18
Q

If the joint is soft and spongy, what is the suggestive diagnosis

A

synovitis or inflammatory arthritis

19
Q

What is dactylitis suggestive of - swollen digits that look like sausages

A

spondyloarthritis

20
Q

What is the correlation with urate level and gout

A

chronic gout is associated with high urate

acute gout can have high, normal or low urate

21
Q

What is the investigation for a connective tissue disease patient who is unwell

A

urinalysis and blood pressure measurement

22
Q

Who is gout rare in

A

premenopausal women

23
Q

What are the joint fluid analysis which are done

A

separate samples for microbiology and cytology for polarising microscopy

24
Q

What are the parameters that are looked for in diagnosing spondyloarthritis

A

Inflammatory back pain with a good response to NSAIDs

Family history of spondyloarthritis

HLA-B27 positive can aid in diagnosis

Elevated CRP and ESR - inflammatory markers

sacroiliitis on MRI

25
What is systemic vasculitis
group of rare autoimmune conditions that cause inflammation of the blood vessels
26
What is fibromyalgia
Centralised widespread pain disorder that is characterised by severe pain and other somatic symptoms - more than 3 months
27
What are the symptoms of fibromyalgia
widespread pain longer than 3 months fatigue - physical, cognitive and emotional Photosensitivity
28