FOM 3.1.1 Flashcards Preview

Foundations of Medicine > FOM 3.1.1 > Flashcards

Flashcards in FOM 3.1.1 Deck (8)
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1
Q

What is the complication that Xiaobin Lu is facing?

A

His two medicines are interacting w/ eachother (buspirone & erythromycin)

2
Q

Why are busprione & erythromycin interacting w/ eachother?

A

Both utilize the CYP3A4 pathway (member of Cyt P450 family of enzymes)

3
Q

How does erythromycin affect the digestion & absorption of buspirone?

A

Erythromycin inhibits buspirone digestion, which increases it’s serum levels.

4
Q

What is the recommended course of action?

A

Bactrim, it uses an alternate digestive pathway.

5
Q

Why can’t a patient take aspirin & ibuprofen?

A

ibuprofen is a competitive inhibitor of COX1 that outcompetes ASA.

6
Q

What is the recommendation if a patient is required to take ASA & ibuprofen?

A

The patient should take the ASA prior to taking the ibuprofen to give it an advantage.

7
Q

Pharmacodynamic interactions

A

Drugs influence each other’s effects directly

8
Q

Are all drugs acting on the same target additive?

A

Depends on the biochemical mechanism