FOM 6.5.3 Flashcards Preview

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Flashcards in FOM 6.5.3 Deck (7)
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1
Q

What were the concerns associated with the birth of baby James?

A

Baby appeared normal except for:
lowest 10% in weight and height
lowest 3% in head size

2
Q

How can fetal alcohol syndrome manifest itself in a clinical setting?

A

Newborns can possess a variety of characteristics such as craniofacial abnormalities, CNS dysfunction, and stunted growth

3
Q

What did this mother reveal about her history with alcohol after follow up questioning?

A

She revealed she often binge drank only on weekends until she found out she was pregnant at 16 wks

4
Q

What is the pathology associated with FAS?

A

DNA damage, disruption in protein synthesis, and inhibition of cellular migration

5
Q

How does alcohol affect the developmental embryology of a potential newborn?

A

During the period of gastrulation, the embryo is very sensitive to teratogens. Alcohol affects cells ability to place organs in the right spot at right time (slowed cell migration). It also affects neural crest cell motility or cell death leading to abnormal craniofacial development. It can also lead to abnormal midline structures.

6
Q

What is holoprosencephaly?

A

Merged forebrain

7
Q

What is synopthalima?

A

It is the failure of the eyes to separate