formative questions - learn well

Question 1

are mucosal membranes highly specialised for function?

Answer 1

yes

Question 2

what is a strain of MRSA which causes NF?

Answer 2

PVL

Question 3

impetigo like mark around the mouth are described as being a …

Answer 3

vesicle

Question 4

is a macule raised or flat?

Answer 4

flat

Question 5

what is a macule described as

Answer 5

an area of skin discolouration

Question 6

when do sweat glands develop

Answer 6

6 months gestation

Question 7

which cells migrate from the skin to the neural crest

Answer 7

melanocytes

Question 8

which layer is most metabolically active

Answer 8

basal

Question 9

which percentage of GP consultations are derm realted

Answer 9

19%

Question 10

boy with type 1 skin - skin but red in sun, crying and rubbing skin

Answer 10

erythropoietic protoporphyria

Question 11

definition of impeding

Answer 11

enables organism to avoid host defence mechanism

Question 12

definition on modulin

Answer 12

causes damage to host indirectly

Question 13

definition of aggressin

Answer 13

causes damage to host directly

Question 14

which cells carry out vit d metabolism

Answer 14

keratinocytes

Question 15

which part is responsible for energy strorage

Answer 15

subcutaneous fat

Question 16

which component is responsible for tensile strength

Answer 16

collagen

Question 17

which cells are responsible for epidermal proliferation

Answer 17

basal cells

Question 18

when does erythropoietic protoporphyria present

Answer 18

early childhood

Question 19

what are the symptoms of EP

Answer 19

discomfort
itch
tingling in sun exposed skin
no clinical signs

Question 20

what is the deficiency of EP And what does it cause build up of

Answer 20

ferrochelastase

protoporphyrin IX

Question 21

what is the lunula

Answer 21

white crescent moon part of nail

its the visible part of the root of the nail

Question 22

what is the hyponychium

Answer 22

the bit underlying the free part of the nail

Question 23

where are langerhan cells formed

Answer 23

bone marrow

Question 24

deficiency in AIP and what does it result in

Answer 24

porphobilinogen deaminase

results in acute neurotoxic reaction in many tissues

Question 25

what are the commonest sweat glands on the face

Answer 25

eccrine glands

Question 26

which glands control temperature regulation

Answer 26

eccrine glands

Question 27

which glands are involved in sent

Answer 27

apocrine glands

Question 28

where are keratinocytes confined to

Answer 28

the epidermis

Question 29

are topical steroids lipophilic or phobic and what does this allow?

Answer 29

lipophilic - this allows passive diffusion across the plasma membrane where they combine with cell receptors and bind to steroid responsive elements in the DNA

Question 30

which layer has big dips in it

Answer 30

prickle cell layer

Question 31

which layer has odland bodies

Answer 31

granular layer

Question 32

which layer has polyhedral cells with lots of desmosomes

Answer 32

prickle cell layer

Question 33

hair growing on cheeks?

Answer 33

PCT

Question 34

how many days does it take for cells to migrate from the basal layer to keratin layer

Answer 34

28 days

Question 35

when are nuclei lost

Answer 35

starts in granular layer and completed in keratin layer

Question 36

what percent of the keratin layer is made from keratin and fillagrin

Answer 36

80%

Question 37

how many cells thick is the granular layer

Answer 37

2-3

Question 38

definition of lichenification

Answer 38

when the skin becomes thick and rubbery as a result of scratching

Question 39

tinea cruris

Answer 39

groin

Question 40

tinea unguium

Answer 40

nails

Question 41

definition of cream

Answer 41

semisolid emulsion of oil in water, containing preservative

Question 42

definition of gel

Answer 42

thickened aqueous solution

Question 43

tuberose sclerosis inheritance pattern

Answer 43

autosomal dominant

Question 44

rosacea relationship to sebaceous glands?

Answer 44

hyperplasia but sebum excretion is normal

Question 45

who does rosace affect

Answer 45

commoner in women but more severe in men

Question 46

HPV warts/verucas types

Answer 46

1-4

Question 47

HPV types for genital warts

Answer 47

6 +11

Question 48

HPV for cervical cancer

Answer 48

16 + 18

Question 49

why are creams more likely to cause an allergic reaction than ointments?

Answer 49

they contain preservatives

Question 50

where are arterial ulcers seen

Answer 50

occur on the foot or the mid shin

Question 51

where are pressure ulcers seen

Answer 51

affect the area of skin in contact with the source of pressure e.g. a bed = sacrum, heels, ischaea, greater trochanters

Question 52

where are venous ulcers seen

Answer 52

lateral or medial malleolus

Question 53

what is the definition of anchoring

Answer 53

the tendency to perceptually lock onto salient features in the patients initial presentation too early int he diagnostic process, and failing to adjust this initial impression in the light of later information

Question 54

what is the definition of avaliability

Answer 54

the disposition to judge things as becoming more likely or frequently occurring, if they readily come to mind