Formative Quiz 1 Flashcards
1
Q
Which 2nd messenger does Adenylyl Cyclase activate?
A
cAMP
2
Q
Describe structure of GPCR in terms of protein domains
A
7 Transmembrane domains connected by 3 intracellular loops and 3 extracellular loops
N terminal on extracellular side when ligand binds, C terminal in cytoplasm where an additional helix domain allows G-protein to bind
3
Q
How many subunits make up P2X receptors?
A
3
4
Q
Which 3 stimuli cause platelet activation?
A
Basal Lamina
Thrombin
ADP
5
Q
Does Gs inhibit or stimulate adenylyl cyclase?
A
Stimulate
6
Q
Name a 2nd messenger activated by phospholipase C, is it membrane bound or cytoplasmic?
A
IP3 - Cytoplasmic
DAG - Membrane bound
