Flashcards in Fructose, Galactose, Lactose Deck (11):
Essential fructosuria enzyme? What are the symptoms? Why is asymptomatic and benign?
Symptoms: fructose in urine and blood
Because fructose does not get trapped in the cells
Fructose intolerance enzyme? What is the difference between essential fructosuria and fructose intolerance? What is inhibited because of the enzyme def.? Why is it inhibited?
Enzyme: Aldolase B
Fructose is phosphorylated in Aldolase B def.
Gluconeogenesis and Glycogenlysis
Phosphate is decreased
Symptoms of Fructose intolerance will come up when you ingest what kinds of food? What will show up in the urine and will the urine show glucose?
Honey, juice, fruit
Symptoms of Fructose intolerance?
Hygoglycemia, jaundice, cirrhosis, vomiting
Galactokinase def. enzyme? If galactose is present in the diet, what will accumulate? Symptoms?
Failure to track objects or develop social smile
Classic galactosemia enzyme? How does this enzyme def. cause damage to organs like the lens?
toxic substances accumulate in the lens
Symptoms of galactosemia? In neonates, this can lead to what kind of sepsis? What two sugars do you have to exclude for these patients?
Cataracts, hepatosplenomegaly, intellectual disability, failure to thrive.
galactose and lactose
"Fructose is to Aldolase B as Galactose is to UridylTransferase (FAB GUT)"
Classic Galactosemia and Fructose intolerance can lead to a depletion of?
In what organs do you only have aldose reductase?
Lens, Schwann cells, retina, kidney.
Lactase is what kind of enzyme? How does gastroenteritis and autoimmune disease cause lactose intolerance? What bug can cause gastroenteritis?
Loss of brush border