fundamentals of neurology Flashcards

1
Q

how will a pt who has a lesion in their brainstem present (in terms of side of body affected)

A

affected side of the face is opposite to affected side of the body (e.g R sides facial symptoms but L sided rest of the body)

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2
Q

who does a brainstem lesion present with this specific mixed distribution

A

most peripheral nerves dessucate in the brainstem while cranial nerves do not decussate (apart from trochlear) - i.e. a lesion on the right side of the brain stem will result in R facial defecit but L body deficit

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3
Q

what distribution of abnormal nuerological function may be seen with severe alcoholism

A

glove and stocking (longest nerves affected first)

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4
Q

if there is a sudden neurological deficit (seconds-minutes) what is the likley cause

A

vascular (stoke, subarach etc.)

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5
Q

if the onset of neurological deficit is hours-days, what is the likely cause

A

inflammatroy (MS flare up, abcess)

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6
Q

if the onset of neurological deficit is weeks-months, what is the likely cause

A

space occupying lesion (tumour, subdural)

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7
Q

if the onset of neurological deficit is months-years, what is the likely cause

A

degenerative (AD, PD)

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8
Q

what to ask about when testing CN I

A

change in smell AND TASTE

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9
Q

what are 2 examples of an abnormal optic disc

A
  1. pale optic disc
  2. swollen optic disc
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10
Q

what 2 nerves are tested by shining a light in the eyes

A

CN II (sensory input of light) and CN III (pupil reflex motor output)

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11
Q

what other area of the brain (not cranial nerves) can be tested by shining a light in the eye

A

brainstem - no pupil reaction is seen

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12
Q

which muscles are controlled by CN III and what is their function (6)

A

superior rectus - eyeball up;
Levator palpabrae superioris - raises upper eyelid;
inferior oblique - elevates, abducts and laterally rotates the eyeball;
inferior rectus - depresses the eyeball;
medial rectus - adducts the eyeball;
sphincter pupillary - pupil constriciton;
cilliary muscles - causes lens to become more symmetrical;

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13
Q

which muscle is controlled by CN IV and what is their function

A

superior oblique - move the eye in the down-and-out position and intort the eye

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14
Q

how does CN IV palsy present

A

vertical diplopia

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15
Q

which muscle is controlled by CN VI and what is their function

A

Lateral rectus muscle - abducts the eye

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16
Q

why is the medial longitudinal fasiculus clinically significant and how will a pt w a lesion here present

A

it is a heavily myelinated interneuron and so it is often affected by demyelinating disorders e.g. MS;

presents with Internuclear ophthalmoplegia

17
Q

what is Internuclear ophthalmoplegia

A

interruption of the neural communication to the CN III subnuclei; leads to inability to perform conjugate lateral gaze (inability to move both eyes together in a single horizontal) and ophthalmoplegia (weakness of eye muscles)

18
Q

what reflex can be used to test for CN V

A

corneal reflex (dont acc perform in OSCE but offer it)

19
Q

what are the 3 sensory divisions of CN V

A

ophthalmic - Forehead and scalp; Frontal and ethmoidal sinus; Upper eyelid and its conjunctiva
Cornea; Dorsum of the nose
maxillary - Lower eyelid and its conjunctiva; Cheeks and maxillary sinus; Nasal cavity and lateral nose
Upper lip; Upper molar, incisor and canine teeth and the associated gingiva
Superior palate
mandibular nerves - Mucous membranes and floor of the oral cavity; External ear; Lower lip; Chin; Anterior 2/3 of the tongue (only general sensation not taste);
Lower molar, incisor and canine teeth

20
Q

what should be looked at when assessing for CN VII palsy (vs higher defecit)

A

eye closure (rather than forehead sparing) - CN VII palsy will not allow for complete eye closure on affected side (e.g. bells palsy)

21
Q

what tests are performed to check hearing loss and what nerve is being tested

A

CN VIII

a combination of
Weber’sand Rinne’s test is performed

22
Q

what is Rinne’s test and what does it indicate

A

bone conduction - tuning fork placed on mastoid process and then moved in front of ear to check if air conduction hearing is better - if air conduction is not better (i.e.the sound cannot be still heard) then there is conductive hearing loss

23
Q

what is Weber’s test and what does it indicate

A

tuning fork placed on the center of forehead and pt is asked where they hear the sound - it should be heard equally in both ears;
Sensorineural hearing loss: sound is heard louder on the side of the intact ear.
Conductive hearing loss: sound is heard louder on the side of the affected ear (due to lower environmental noise and this higher conductive ability)

24
Q

what test can be used to assess vertigo

25
what nerves does uvula deviation test for and what is the finding
IX and X Uvula away from affected side, tongue towards
26
if there is acute CN II presentation what other structures should be checked
carotids (listen for bruits)
27
if a painful CN III palsy is seen, what may have caused it (2)
1. direct compression of the nerve by an aneurysm; 2. subarachnoid hemorrhage in the vicinity of an aneurysm
28
what anatomical position is known for tumour growth and what nerve can this affect
meckel's cave, this an affect CN V
29
what is the initial investigation for acute vertigo
also needs a scan
30
what are the efferent pathways in the DH (motor - 6)
pyramidal tracts: lateral corticospinal, anterior corticospinal extra pyramidal: rubrospinal, reticulospinal, oticospinal, vestibulospinal
31
what are the afferent tracts in the DH (sensory - 3)
1. dorsal column (medial lemniscus) 2. spinocerebellar 3. anterolateral
32
why is the anatomy of the DH important clinically
it explains why damage to the SC may only result in certain sensations/motor actions being affected
33
why might a lesion on one side of the DH cause different symptoms in different legs of the body
dessucation occurs in the DH for some sensations/actions (e.g. pain, temp) but it occurs higher up for other e.g. power, vibration => a lesion in one side will affect different halves of the body differently (e.g. R sided lesion may cause L sided affected pain but R sided affected power)
34
what is brown-sequard syndrome
a rare neurological condition that happens when damage to your spinal cord causes muscle weakness or paralysis on one side of your body and a loss of sensation on the opposite side
35