Fungi Flashcards
(31 cards)
fungal cells have this instead of cholesterol
ergosterol
fungal cells have these two things in the cell wall
chitin and glucans
risk factors for fungal infection
immunosuppression, warm/wet environment, antibiotic use, indwelling hardware
one of the preps used to visualize fungi
KOH
Amphotericin B is a ___ that targets ____
polyene, ergosterol
the ______s are a class of drugs that inhibit ergosterol synthesis
azoles
terbinafine is a ____ that works by ____
allylamine, inhibit ergosterol synthesis
drugs that end in fungin are ______ and work by ____
echinocandins, inhibit glucan synthesis
histoplasmosis geographical region
Ohio/Mississippi River valley
which fungal infection has the Gohn complex after healed
histoplasmosis (like TB)
diagnosis of histoplasmosis
urine or seum antigen assay, culture
treatment for histoplasmosis
itraconazole, amphotericin B
geographical region for blastomyces dermatitidis
North Central US
where does blastomyces disseminate
skin and bone
blastomycosis has clusters of ____ (cell type)
neutrophils
broad based budding yeast
blastomyces dermatitidis
blastomycosis has (caveating/noncaseating) granulomas
non
blastomycosis treatment
itraconazole, amphotericin B
region of coccidioides immitis
California
form of inhaled blastomyces
canidia
form of inhaled coccidioides
arthroconidia
thrush
oropharyngeal candidiasis
can you scrape off thrush?
yes
treatment for candidiasis
echinocandins, azoles if susceptible
