Gas Exchange Flashcards
(47 cards)
What determines cellular oxygenation?
Oxygen supply and oxygen demand
What factors affect oxygen supply?
Arterial oxygen content and cardiac output
What two factors determine arterial oxygen content?
PaO2 and SaO2
What determines PaO2? (1 thing)
Alveolar gas exchange
What factors affect alveolar gas exchange?
Composition of inspired air, ventilation, pulmonary perfusion, alveolar capillary diffusion
What 3 factors determine ventilation?
Compliance, resistance, neuromuscular function
What factors determine pulmonary perfusion?
Central perfusion and vessel patency
What is the formula for cardiac output (CO)?
CO = HR x SV
What factors affect metabolic demand?
Temperature, stress, physical activity
What is gas exchange?
Oxygen is transported to cells and CO2 is transported away from the cells
What 10 factors affect gas exchange?
Alveolar-capillary diffusion, surface area, diffusion distance, pressure gradient, ventilation, resistance, compliance, neuromuscular function, pulmonary perfusion, vessel patency, central perfusion
What is pneumonia?
An infectious and inflammatory process affecting alveoli and connective tissue responsible for gas exchange
What triggers the inflammatory response in pneumonia?
A germ (either bacteria or virus) settling in the alveolar wall
How is pneumonia transmitted?
By droplets, blood, intubations
What do goblet cells do in the mucociliary defense system?
Produce mucus to trap foreign particles
What is typical/bacterial pneumonia characterized by?
Exudate filling alveoli and leading to consolidation
What is the onset of typical pneumonia? What type of cough?
Rapid onset with productive cough
What is atypical/viral pneumonia characterized by?
Inflammation affecting the alveolar septum and interstitium
What is the onset of atypical pneumonia? What type of cough?
Gradual onset with non-productive cough
What are the types of pneumonia?
- Bronchopneumonia: alveoli are consolidated
- Lobar: a full lobe is consolidated
- Interstitial (atypical): alveoli look normal, but interstitial tissue is swollen
What are some risk factors for pneumonia?
- Smoking
- Alcohol abuse
- IV drug use
- Malnutrition
- Living in close quarters
- COPD
- Cystic fibrosis
- Cancer
- Immobility
- History of lung infections
- Weakened immune function
What is a consolidated area?
An area full of fluid
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What is the normal range for SpO2?
95-100% on room air, 88-92% if they have COPD