Gases

Question 1

Enflurane
MAC?
BG Partition coefficient?
VP?

Answer 1

1.7 MAC
1.9 BG coefficient
175 VP

Question 2

Enflurance

CV

Answer 2

> HR

«

Question 3

Enflurane

Resp Effects

Answer 3

> > RR
< response to hypercapnia,&raquo_space;PaCO2
No hypoxic drive
< mucociliary fx

Question 4

Enflurane

Cerebral

Answer 4

> > ICP
CSF secretion/resistance to outflow
EEG changes, tonic/clonic seizure

Question 5

Sevoflurane

CI

Answer 5

Malignant Hyperthermia

Severe Kidney Dysfunction

Question 6

Halothane

CI

Answer 6

Liver Disease
Hypovolemia
Aortic Stenosis
Pheochrom
Malignant Hyperthermia
Liver Dsfx (unexplained after halothane exp)

Question 7

Desflurane

CI

Answer 7

Malignant Hyperthermia

Question 8

Isoflurane

CI

Answer 8

Malignant Hyperthermia

Question 9

Enflurane

CI

Answer 9

Malignant Hyperthermia
Pre-existing kidney disease
Seizure disorder (known/suspected)

Question 10

N2O

CI

Answer 10

Pulm HTN
 B12 inhibited
1st Trimester 
Air Cavity: 
 air emboli, Pneumo,
  acute intestine obstruction, 
 intracranial air, tympanic grafting

Question 11

Enflurane

Structure

Answer 11

Halogenated

Methyl Ethyl Ether

Question 12

Isoflurane

Structure

Answer 12

Halogenated

Methyl Ethyl Ether

Question 13

Desflurane

Structure

Answer 13

Fluorinated

Methyl Ethyl Ether

Question 14

Sevoflurane

Structure

Answer 14

Fluorinated

Methyl Isopropyl Ether

Question 15

Halothane

Structure

Answer 15

halogenated

alkane derivative

Question 16

Halothane
MAC?
BG Partition coefficient?
VP?

Answer 16

MAC 0.76
BG 2.3
VP 243

Question 17

N2O
MAC?
BG Partition coefficient?
VP?

Answer 17

MAC 104
BG 0.47
VP 38,770

Question 18

Isoflurane
MAC?
BG Partition coefficient?
VP?

Answer 18

MAC 1.2
BG 1.4
VP 239

Question 19

Desflurane
MAC?
BG Partition coefficient?
VP?

Answer 19

MAC 6
BG 0.42
VP 680

Question 20

Sevoflurane
MAC?
BG Partition coefficient?
VP?

Answer 20

MAC 2.05
BG 0.69
VP 157

Question 21

Which 2 agents depress ventilation the most?

Answer 21

Desflurane

Enflurane

Question 22

Which agent least depresses ventilation?

Answer 22

Halothane

Question 23

Which 2 agents most depress baro reflex

Answer 23

Halothane

Sevoflurane

Question 24

What agent most degraded by soda lime?

Answer 24

Sevoflurane

Des least degraded

Question 25

Which 3 agents depress cerebral metabolic rate the most?

Answer 25

Isoflurane Desflurane sevoflurane

Question 26

2 agents that cause most myocardial depression?

Answer 26

Enflurane | Halothane

Question 27

Which agent causes greatest > in CBF?

Answer 27

Halothane

Question 28

Brain up take of anesthetic depends on 4 factors:

Answer 28

1- blood solubility 2- Cardiac Output 3- Alveolar Ventilation 4- Inspired Concentration

Question 29

2 most important factors of > in alveolar pressure for inhalation agent?

Answer 29

Inspired concentration | blood solubility

Question 30

Second Gas Effect

Answer 30

High concentration of N2O accelerate rate of uptake of simultaneously inhaled volatile agent

Question 31

MAC r/t to potency

Answer 31

lower MAC = | higher potency

Question 32

What MAC prevent movement in 95% of patients?

Answer 32

1.3 MAC

Question 33

7 things that < MAC ?

Answer 33

``` Increasing Age Hypothermia CNS Depressant acute EtOH intoxication A2 agonist Pregnancy < excitatory NTs ```

Question 34

What age is highest MAC associated?

Answer 34

infant, 1-6 months (except for Sevo, highest 0-30 days -neonates)

Question 35

Metabolism of inhaled anesthetics

Answer 35

Halothane 15-20% Enflurane 2% Isoflurane 0.2% Desflurane 0.02% Sevoflurane 3-5%

Question 36

Which inhaled agent has preservative?

Answer 36

Halothane | Thymol

Question 37

What is the upper limit for inhaled agent w/ N20 in OR? Volatile used alone?

Answer 37

N2O 25 ppm volatile 0.5 ppm Alone, volatile 2 ppm

Question 38

Two pungent inhaled agents?

Answer 38

Desflurane | Isoflurane

Question 39

Which inhaled volatile agent has least drop in BP?

Answer 39

Sevoflurane

Question 40

Which 2 inhaled agents < SVR the most?

Answer 40

Desflurane | Isoflurane