Gastric secretions Flashcards

1
Q

functions of the stomach

A

starting point for digestion
mixes food with gastric secretions to produce semi liquid chyme
stores food before passing to small intestine
secretes gastric juice from gastric glands

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2
Q

how is relaxation of orad region dirven

A

by vagus nerve during swallowing, opens lower sphincter allowing storage

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3
Q

caudad region function

A

generate force to mix contetns and push towards duodenum

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4
Q

what determines delivery of chyme to the duodenum

A

strength of antral wave or pump and opening of pyloric sphincter

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5
Q

what is the strenght governed by

A

gastric and duodenal factors

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6
Q

gastric factors

A

volume of chyme in stomach;

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7
Q

consistency of chyme in relation to emptying

A

the thinner the better

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8
Q

duodenal factors

A

delays emptying

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9
Q

triggers for delay

A

fat
acid
hypertonicity

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10
Q

what is HCL secreted by

A

parietal cells

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11
Q

function of hcl

A

activates pepsinogen to pepsin

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12
Q

role of intrinsic factor

A

binds vitamin b12, facilitating absorption

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13
Q

role of gastroferrirn

A

binds fe2+ to facilitate absorption

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14
Q

role of histamine

A

stimulates hcl secretion

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15
Q

what is gastrin secreted by

A

g cells, stimulates hcl secretion

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16
Q

what is somatostatin secrted by

A

d cells, inhibits hcl secretion

17
Q

what inhibits hcl secretion

A

somatostatin

18
Q

what stimulates hcl secretion

A

gastrin and histamine

19
Q

what is the cephalic phase

A

phase before food enters

20
Q

what happens during cephalic phase

A

thought, smell and taste stimulates vagus nerve to relase acc which directly activates parietal cells > hcl production

21
Q

what do parietal cells secrete

A

hcl, intrinsic factor, gastrin and histamine

22
Q

what is the gastric phase

A

when food is in the stomach

23
Q

what is the intestinal phase

A

once food has exited the stomach

24
Q

where is CCK secreted from

A

i cells in duodneum

25
Q

what is cck related to

A

gallstones

26
Q

cck function

A

promotes gallbladder contractility, causing the release of bile into the small intestine

27
Q

another function of cck

A

increased pancreatic secretions

28
Q

secretin role

A

increases secretion of bicarbonate-rich fluid from pancreas and hepatic duct cells