Gastric secretions Flashcards
(28 cards)
functions of the stomach
starting point for digestion
mixes food with gastric secretions to produce semi liquid chyme
stores food before passing to small intestine
secretes gastric juice from gastric glands
how is relaxation of orad region dirven
by vagus nerve during swallowing, opens lower sphincter allowing storage
caudad region function
generate force to mix contetns and push towards duodenum
what determines delivery of chyme to the duodenum
strength of antral wave or pump and opening of pyloric sphincter
what is the strenght governed by
gastric and duodenal factors
gastric factors
volume of chyme in stomach;
consistency of chyme in relation to emptying
the thinner the better
duodenal factors
delays emptying
triggers for delay
fat
acid
hypertonicity
what is HCL secreted by
parietal cells
function of hcl
activates pepsinogen to pepsin
role of intrinsic factor
binds vitamin b12, facilitating absorption
role of gastroferrirn
binds fe2+ to facilitate absorption
role of histamine
stimulates hcl secretion
what is gastrin secreted by
g cells, stimulates hcl secretion
what is somatostatin secrted by
d cells, inhibits hcl secretion
what inhibits hcl secretion
somatostatin
what stimulates hcl secretion
gastrin and histamine
what is the cephalic phase
phase before food enters
what happens during cephalic phase
thought, smell and taste stimulates vagus nerve to relase acc which directly activates parietal cells > hcl production
what do parietal cells secrete
hcl, intrinsic factor, gastrin and histamine
what is the gastric phase
when food is in the stomach
what is the intestinal phase
once food has exited the stomach
where is CCK secreted from
i cells in duodneum