Gastro Flashcards

(47 cards)

1
Q

what gets absorbed

in distal ileum

A

B12, Bile

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2
Q

Folic acid gets absorbed

in

A

First part of intestine

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3
Q

What gets aAbsorbed from proximal as well as distal si

A

GIucore
AA
Lipids

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4
Q

Mined anemia may occur

due to malabsorption in

A

Proximal ?

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5
Q

order of sequence absorption of fat

A

TG → Fat globules → ED → FA → micalle → enterocyte → FA → TG → chylomicrons → lymph → blood →

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6
Q

Bacterial overgrowth synchome

A

conj bile→ un conj bile

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7
Q

Causes of fat malabsorption

A
Decreased bile
Decreased lipase
 Mucosal disease of intestine
Decreased chylomicrons
lymphangiectasia
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8
Q

Ix Fat malabsorption

A

72 hour sfool fat
Steatorrea > 7 g/ dy
spot test
Breath test

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9
Q

Triglyceride used for breath test

A

tripalmitin
triolain
tri octaneon

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10
Q

Monosacharides in
intestine alesorbed
by

A

SGLT -1(glucose and galactose )

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11
Q

Fructose transporter

A

GLUT_ 5

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12
Q

D- Xylose is a test of

A

mucosa of proximal SI
25g show wine
<4.5 g positive test

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13
Q

False positive d- xylose test

A

Pyloric
stenosis
Renal failure
Third space shifting

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14
Q

R- Binder

A

Transcobalamine
haptocorin
Vit B 12 alesorption
secreted by salivary glands

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15
Q

Cubulin receptors

found in

A

Distal SI

IF receptors

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16
Q

Role of pancreatic enzymes

in Vit B12 absorbtion

A

Breaks down

transcobalamin + vit B12

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17
Q

C auses of malabsorption Vit B12

A

Pernicious Anemia
Pancreatic diseases
Diseases of distal
SI

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18
Q

SCHILLING TEST

A
Vit B12 gold Std
ing of vit B12 IM
24 hour urine 
< 10%
add IF
add Pancreatic enzymes
CT contrast?
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19
Q

coeliac spru e a/ w

A
Trype I DM
Ig A def
Dermatitis herpeteformis
Downs
Turners
20
Q

Coeliac spruce affects which part of SI

A

Proximal more

21
Q

. Anti tTg

A

most sensitive specific

antibody for coeliac sprue

22
Q

anti bodies coeliac sprue

A

Endomysial Ab
guinea pig tTG
human ttG
IGA IGG anti glia din

23
Q

Ix coeliac sprue

A

ab
biopsy
Reversal of changes *****

24
Q

Flat villi with crypt

hyperplasia

A

hallmark of coeliac sprue

25
Indication for glucocorticoids in coeliac
Refractory | crisis
26
Tropical sprue caused by
klebsiella pneumoniae Enter obacter cloacae E. coli
27
Mononuclear cell infiltrate throughout the lamina | propria
Biopsy- tropical sprue
28
Rx for tropical sprue
Doxycyclihe or tetra cycline (250 Qid) x 6 months Folic acid Vit B 12
29
Whipple s disease associations
``` migratory poly arthritis pan card itis dementia supranuclear ophthalmoplegia seizures cerebellar ataxia polyserositis hepatos planomegaly ```
30
PAs positive macrophages
whipple's disease
31
Rx coeliac sprue
Inj ceftriaxone or Inj meropenam X2mweeks or? Trimethoprim + sulphamethOxazole
32
which IL helps in inhibition of | Immune system against food
1L- 10
33
Co mmon feature UC CD
``` Age se x - Turners Diarrhea Anorexia Nausea, vomiting fever, weight loss Euleaintes tinal manifestation ```
34
gross blood in stool and mucous common in
UC
35
smoking appendicectomy IBD
doubt?
36
ocP and infection risk factor for which IBD
C D
37
most commonly affected | site in uc
Rectum> sigmoid
38
Rectal sparing IBD
CD
39
Uc cannot affect
SI
40
Trans mural 11BD
CD
41
Collar button ulcer
uc
42
Non caseating granuloma . IBD
CD
43
strictures and skip lesion | which IBD
CD
44
Pyoderma gangsinosun IBD
UC> CD
45
Ocular manifestations of IBD
conjunctivitis Anterior uveitis episcleritis
46
Ix IBD
ESR CRP Leucocytesis anemia hypoalbuminea PANCA* ,ASCA, OMP C ,I2 ,anti c - .... Fecal cal protectin, lactoferrin
47
Classification criteria | for uc
MAYO | TRUELOVE and WITTS