GASTROENTEROLOGY Flashcards

(92 cards)

1
Q

An exclusively breastfed infant has not stooled
for 5 days with no other symptoms. The stool is
soft with no rectal bleeding. The infant is gaining weight

A

Reassurance (breastfed infants may go several
days or even a week between bowel movements)

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2
Q

A 1-week-old child with frequent spit-ups,
otherwise doing well

A

Reassurance (newborn reflux is normal)

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3
Q

A 3-week-old first newborn boy presents with
nonbilious projectile vomiting, hypochloremic,
hypokalemic metabolic alkalosis, and dehydration

A

Pyloric stenosis

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4
Q

What are the upper GI series useful for?

A

To rule out anatomic or motility problems. Does
not diagnose reflux

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5
Q

What is the next best step in cases with suspected pyloric stenosis?

A

Abdominal US (pylorus)

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6
Q

Weight loss, abdominal pain, nausea, effortless
postprandial regurgitation after at least 1 meal
daily for 1 month, regurgitated food occasionally reswallowed, rechewed, or spit out

A

Rumination syndrome

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7
Q

Child with no known health problem woke up
suddenly vomiting blood. The child is stable and
acting normal. What is the most likely cause?

A

Epistaxis (nose bleeding is the most common
source in healthy children)

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8
Q

Nausea and vomiting every 1–2 months, each
episode lasts for few hours, otherwise healthy, no symptoms in-between episodes, positive family history of migraine

A

Cyclic vomiting syndrome

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9
Q

A 7-year-old healthy child, with periumbilical
abdominal pain worse in the morning prior to
school, improves during weekends with normal
growth parameters

A

Reassurance (functional abdominal pain)

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9
Q

Adolescent presents with recurrent episodes of
abdominal pain, diarrhea, and sometimes
constipation in the previous 3 months. No weight loss and all labs are normal. What is the best treatment?

A

Peppermint oil, diet modifications, cognitive
behavioral therapy

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10
Q

High achieving adolescent complains of crampy
abdominal pain, diarrhea, and at other times,
constipation; pain is relieved with stooling

A

Irritable bowel syndrome

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11
Q

A mother brought her toddler with a diaper full of undigested food, the child is holding a large bottle of apple juice

A

Toddler diarrhea

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11
Q

What is the major concern of using antimotility
drugs such as Loperamide?

A

May induce ileus

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12
Q

The best management of toddler’s diarrhea

A

Juice restriction and allow normal dietary fat

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13
Q

Child with a low-grade fever, 6 episodes of
diarrhea, otherwise reassuring medical exam.
What is the treatment of choice?

A

Oral rehydration therapy (avoid anti-diarrheal
agents)

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14
Q

An infant presents with bright red blood stool,
poor weight gain, diarrhea, and fussiness; the
infant is breastfeeding, supplemented with
standard infant formula; stool guaiac test is
positive

A

Cow milk protein intolerance

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15
Q

Child with dysphagia, recurrent food impaction;
biopsy shows an increased eosinophil?

A

Eosinophilic esophagitis

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15
Q

Child accidentally swallowed caustic liquid 6 h
ago, presents with dysphagia, oral pain, chest
pain, nausea, and vomiting

A

Endoscopy in 12–24 h after ingestion

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16
Q

Adolescent with recurrent headaches takes
ibuprofen as needed, presents with dysphagia and chest discomfort (does not like to drink water with medicine)

A

Pill-induced esophagitis

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17
Q

4 weeks passed and the coin still in the stomach
with no symptoms

A

If the coin does not pass through the stomach by 4 weeks or if the patient is symptomatic, removal by endoscopy should be considered

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17
Q

Swallowed a coin, no symptoms, and radiograph showed the coin still in the esophagus

A

Observe for 12–24 h, removal of the coin if it
does not pass to the stomach or if the patient
became symptomatic

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18
Q

Swallowed a coin, no symptoms, and radiograph showed the coin in the stomach

A

Checking the stool for passage for 4 weeks, with
weekly radiographs, if indicated

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18
Q

Swallowed a button battery (BB), and passed to
the stomach with symptoms

A

Immediate removal

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19
Q

Swallowed a coin, excessive drooling, and chest
pain, and radiograph showed the coin still in the
esophagus

A

Immediate removal

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20
Swallowed a BB that got stuck in the esophagus
Immediate remova
20
Swallowed a BB, and passed to the stomach without symptoms
Urgent removal (if age < 5 and BB ≥ 20 mm) Elective if not moving (checking the stool for passage for 4 weeks, with weekly radiographs)
20
The best and most definitive test for peptic ulcer disease
Endoscopy
20
Swallowed small pieces of magnet metals; the abdominal radiograph showed the pieces in the stomach
Immediate remova
21
An older child with bloating, constant burping, sharp epigastric pain that awakens the child from sleep
Helicobacter pylori infection
22
The most common cause of chronic gastritis in pediatrics
H. pylori
23
What is the treatment of H. pylori infection?
Amoxicillin or metronidazole + clarithromycin + PPI for 2 weeks
23
Infant suddenly develops bilious vomiting, abdominal distension, tenderness, and fussiness. What is the diagnostic test of choice?
Upper GI series with follow through
24
In the infant above, the GI series shows a bird’s beak sign of the second portion of the duodenum
Volvulus
25
Intermittent crampy abdominal pain, lethargy, bilious vomiting, and a palpable mass in the right upper quadrant
Intussusception
25
What is the best initial diagnostic test of choice in cases of intussusception?
Abdominal US (target sign, reflecting a segment of bowel trapped within a distal segment of bowel)
25
What is the therapeutic procedure of choice in cases of intussusception?
Air contrast enema (diagnostic and therapeutic)
26
Down syndrome, bilious vomiting, double bubble sign on KUB
Duodenal atresia
27
A mother brought her 9-month-old girl with a diaper full of red, maroon stool; the physical exam is normal, and the infant is feeding well and smiling (she is receiving an antibiotic for AOM)
Most likely the medicine, e.g., cefdinir may change the stool color to maroon color (bloodlike color)
28
A 2-year-old boy, frank rectal bleeding, anemia, no pain, no other symptoms
Meckel diverticulum
29
What are the 2 most common ectopic tissues found in Meckel diverticulum?
Gastric and pancreatic
29
Most common cause of rectal prolapse in the USA
Constipation
30
Infant, failure to thrive, rectal prolapse
Cystic fibrosis
30
How is Meckel diverticulum diagnosed?
Technetium 99 scan
30
Rectal bleeding, large and hard stool in the diaper
Anal fissure
30
The most common cause of rectal bleeding in infants
Anal fissure
30
A 2-year-old boy with chronic constipation, ineffective laxatives, fails to pass meconium in the first 48 h of life, explosive stools on rectal exam, KUB showed very distended colon
Hirschsprung disease
31
A 48-h old boy did not pass the meconium; the abdomen is slightly distended
Hirschsprung disease
31
Most accurate diagnostic test for Hirschsprung disease
Full-thickness rectal biopsy performed by surgery
32
Persistent epigastric abdominal pain, vomiting; the pain is referred to the back, tenderness in the epigastric region, elevated amylase, and lipase enzymes
Acute pancreatitis
32
Child with type 1 diabetes mellitus and recurrent abdominal pain
Celiac disease
32
Child with Down syndrome, intermittent abdominal pain, and failure to thrive
Celiac disease
32
Jaundice, abdominal pain, and fever
Cholangitis
32
Child with a history of recurrent abdominal pain presents with fever, abdominal pain, bloody diarrhea, migratory arthritis, erythema nodosum, ankylosing spondylitis, elevated ESR, positive P-ANCA
Ulcerative colitis
32
Recurrent aphthous ulcers, abdominal pain, weight loss, perianal lesions, positive anti- Saccharomyces antibodies
Crohn’s disease
32
Hydrops of the gallbladder can be seen in
Kawasaki disease
32
What is the most common complication of cholelithiasis?
Pancreatitis
32
Jaundice, abdominal pain, and a palpable mass in the right upper quadrant
Choledochal cyst
33
Conditions associated with an increased incidence of cholelithiasis
Sickle cell anemia, chronic total parenteral nutrition (TPN), adolescent pregnant females
33
A 3-year-old boy presents with failure to thrive, difficulty walking; the metabolic panel shows elevated aspartate transaminase (AST) and alanine transaminase (ALT). Total bilirubin, prothrombin time, blood glucose, TSH and free T4 are all normal, negative hepatitis viral panel. What is the test of choice in this case?
Creatinine phosphokinase (CK) (muscular dystrophy most likely)
33
What are the sources of transaminases (ALT and AST)? It is important to consider other sources of transaminases if they are elevated and the liver function is normal
Liver, heart, muscles, kidney, and brain
34
The best laboratory test for acute hepatitis A
Anti-HAV IgM
35
A mom is asking about prophylaxis for her 4-month-old child after she was recently diagnosed with hepatitis A?
Administer IG as prophylaxis (< 1 year)
36
Prophylaxis of a 3-year-old child exposed to a documented case of hepatitis A in a child care center
Hepatitis A vaccine (> 1 year)
37
All hepatitis viruses are composed of RNA except
Hepatitis B virus is composed of DNA
38
Which virus infection must have hepatitis B?
Hepatitis D
39
Child with a family history of lupus disease presents with jaundice, hepatomegaly, weight loss, loss of appetite, positive anti-smooth muscle antibodies
Autoimmune hepatitis
40
One week with jaundice, hepatomegaly, slightly elevated ALT and AST, prolonged PT that is not responding to IV vitamin K, and recurrent hypoglycemia
Acute hepatic failure
41
An 8-year-old boy has recurrent jaundice, slightly elevated indirect bilirubin; physical examination and all other labs are normal
Gilbert syndrome
42
A 1-day-old boy with intense jaundice, unconjugated bilirubin is 25 mg/dL, and no conjugated bilirubin; and poor response to phototherapy
Crigler–Najjar syndrome type I (exchange transfusion is warranted)
43
Mild conjugated hyperbilirubinemia with black liver
Dubin–Johnson syndrome
44
An infant with jaundice, dark urine, light-colored stool, hepatomegaly, and elevated conjugated bilirubin
Biliary atresia
45
What is the most valuable study for neonatal biliary atresia?
Percutaneous liver biopsy
46
If liver biopsy confirmed biliary atresia, what is the next appropriate test?
Intraoperative cholangiography
47
Adolescent presents with depression, psychosis, and elevated liver enzymes
Wilson disease
48
Which mineral is affected in Wilson disease?
Copper (excess)
49
How to establish the diagnosis of Wilson disease
Ceruloplasmin < 20 mg/dL. Hepatic copper > 250 ug/g dry weight. Urine copper > 100 ug/24 h. Presence of Kayser–Fleischer rings
50
Broadened forehead, jaundice, pulmonary stenosis, and butterfly hemivertebrae
Alagille syndrome
51
Abdominal mass, elevated liver enzyme, and high serum alpha-fetoprotein
Hepatoblastoma
52
A 3-month-old, failure to thrive, extreme pruritus, steatorrhea, very high-conjugated bilirubin, hepatosplenomegaly, mutilated skin, elevated serum alkaline phosphatase, and normal gammaglutamyl transferase (GGT)
Progressive familial intrahepatic cholestasis (PFIC) type 1
53
Prognosis of all forms of PFIC
Lethal during childhood unless treated early
54
Hematochezia, intestinal polyp, pigmented penile lesion, large head, café-au-lait spots, intellectual disability
Bannayan–Riley–Ruvalcaba syndrome
55
> 5 juvenile polyps
Juvenile polyposis
56
What is the next step in children with ≥ 5 juvenile polyps or any number of adenomatous intestinal polyps?
Genetic testing
57
100 or more adenomatous polyps in the large and/ or small intestines
Familial adenomatous polyposis
58
Intestinal polyps, osteoma of the mandible, papillary carcinoma of thyroid, and hepatoblastoma
Gardner syndrome
59
Intestinal polyps and brain tumor
Turcot syndrome
60
Intestinal polyps, hematochezia, mucocutaneous freckling, and a family history of polyposis
Peutz–Jeghers syndrome (increases the risk of cancer)
61
Hamartomas involving many areas of the body, e.g., skin, oral mucosa, thyroid, breast, and colon
Cowden syndrome
62
Associated risks of Cowden syndrome
Cancer, e.g., thyroid cancer
63
Hemihypertrophy, very large extremities, epidermal nevus, hamartomatous polyps, intellectual disability
Proteus syndrome
64
Potential risks of Proteus syndrome
Deep vein thrombosis (DVT) and thromboembolism
65
The best diagnostic test for lactose intolerance
Hydrogen breath test