Gastrointestinal Flashcards
(140 cards)
Liver segments by portal and hepatic veins
Portal vein: superior/inferior
Middle hepatic vein: right/left
Left hepatic vein: 2,3/4
Right hepatic vein: 5,8/6,7
Hepatic segment vasculature
Central:
portal triad—> portal vein, hepatic artery, bile duct
Peripheral:
venous —>hepatic vein—>IVC
Caudate:
Direct to the IVC
Routine contrast enhanced CT usage
Portal venous phase(70s after injection)
Hepatic steatosis, cirrhosis
Most metastasis ( not hyper vascular)
Some breast Mets are iso in portal phase/detected on unenhanced
Arterial phase CT usage in liver
20-25 s after injection
Primary liver masses (hyper vascular)
Optimal view—> late arterial (35 s)
NAFLD categories
Steatosis
Steatohepatitis
Metabolic syndrome
NAFLD
Obesity
Insulin resistance
Dyslipidemia
Hepatic steatosis on CT
Un-enhanced:
Liver attenuated 10 HU less than spleen
Contrast enhanced: liver 25 HU less than spleen in pvp
Fatty liver on MRI
In and out of phase GRE MRI
complete signal loss on out of phase
In phase: water+fat
Out of phase:water-fat
Decreased signal on in phase MRI
Hepatic iron overload
Increases TE—> longer dephasing—> exaggerated T2*
Focal liver fat characteristics
No mass effect
Vessels run through it
Location:
Gallbladder fossa/ subcapsular/periportal/
Hyper echo on US and hypo on CT
Liver amyloidosis
Decreased attenuation on CT
Wilson disease on CT
Copper : basal ganglia/cornea/liver
Liver:
Hyper on CT—> multiple nodules—>hepatomegaly—>cirrhosis
Excess hepatic iron accumulation pathways
Within hepatocytes: hemochromatosis
Increased uptake in RES: kupffer cells/ hemosiderosis
Iron overload liver imaging
MRI: hypo compared to paraspinal muscle
Hemochromatosis vs Hemosiderosis
Hemochromatosis: spleen and bone marrow are spared
Involves pancreas,myocardium,skin,joint/ cause cirrhosis/ tx: phlebotomy
Hemosiderosis: spleen and bone marrow are involved/ no cirrhosis/ tx: iron chelator
Hypo-attenuated liver on CT
Fatty liver Hepatic amyloid ( rare)
Hyper attenuated liver on CT
>75 HU iron overload Medication: amiodarone, gold, methotrexate Copper overload Glycogen excess
Viral hepatitis imaging
Normal CT
Gallbladder wall thickening
Periportal edema
DDx for multiple tiny hypo hepatic lesions
Candidiasis (involves spleen/ rim enhanced/ immunocompromised)
Mets
Lymphoma
Biliary hamartoma
Caroli disease (dilatation of intrahepatic bile ducts/fibrocystic anomalies of the kidneys)
Causes of liver abscess
Diverticulitis Appendicitis Crohn Bowel surgery Ascending cholangitis ( less common)
E.Coli
Hepatic abscess on imaging
Mimics Mets
CT: ring enhanced
MRI: central hyper on T2/ irregular wall with late enhancement/ perilesional enhancement
Hepatic echinococcosis on imaging
CT: well defined hypo mass with floating membrane and peripheral calcification
US: hypoechoic mass with hyperechoic undulating membrane
Cirrhosis forms
Micronodular: metabolic causes
Macronodular: post viral
Cirrhosis on imaging
Early: preportal space expansion Caudate enlargement Caudate/right lobe>0.65 Empty gallbladder fossa sign
Secondary:
Portal HTN—> splenomegaly, portosystemic collaterals, varies
Gall bladder wall thickening
Gamna-Gandy bodies( splenic microhemorrhage)