Gastrointestinal system 2 Flashcards

(34 cards)

1
Q

pancreas

A

lumpy lobular organ
duct delivers pancreatic secretions to duodenum
islet releases insulin and glucagon

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2
Q

pancreatic acini

A

simple cuboidal epithelium
primary lipase production and release of pancreatic juice into the duct

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3
Q

what happens when chyme reaches the duodenum

A

secretin and CCK are released triggering pancreatic secretion

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4
Q

pancreatic juice

A

amylase
lipase
nucleases
inactivated proteolytic enzyme for activation in small intestine
(trypsinogen, chymotrypsinogen, procarboxpeptidase, proelastase)

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5
Q

liver

A

4 lobes, regenerative if blood supply not affected
falciform ligament
porta hepatis - blood vessel to to live - hepatic artery and hepatic portal vein to inferior vena cava

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6
Q

histology of the liver

A

sinusoids lining - endothelial cells, stellate macrophages (Kupffer cells)
adjacent veins
liver lobules - 6 portal triads
bile canaliculi (duct)

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7
Q

liver functions

A

metabolic function
haematological function - largest blood reservoir, plasma proteins, removes old blood cells
bile production

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8
Q

what regulates bile secretion

A

CCK

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9
Q

what is bile made of

A

cholesterol, lipids, bilirubin, water, ions

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10
Q

role of the gall bladder

A

concentration of bile for when needed for high lipid content

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11
Q

gallbladder stones

A

(gallstones)
cholecystitis
when bile is too concentrated
high fat diet

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12
Q

small intestine

A

90% of absorption
mesentery proper (blood and lymphatic vessels, nerves)
circular folds

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13
Q

purpose of fold in small intestine

A

increased surface area for absorption not expansion

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14
Q

histology of small intestine

A

villi lined simple columnar epithelium with microvilli
brush border
lamina propria capillaries
lacteals

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15
Q

duodenum

A

Connection from stomach, curves into C shape
Less circular folds
Mixing bowl for chyme, pancreatic juice and bile
Main function is receiving chyme and neutralising acid

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16
Q

duodenum secretions

A

Gastrin, CCK, secretin
Mucous (pH) and urogastrone (inhibits gastric acid)

17
Q

duodenal submucosa glands

A

Brunner’s patches
mucous and urogastrone

18
Q

jejunum

A

bulk of chemical digestion and absorption
circular folds prominent at middle part before decreasing

19
Q

ileum

A

ends with ileocecal valve, sphincter controlling entry to coecum
distal part lacks circular folds
contains payers patches

20
Q

payers patches of ileum

A

lymphoid nodules that gatekeep bacteria of large intestine
close to large intestine entrance
rich in macrophages

21
Q

functions of large intestine

A

water absorption
excretion
vitamin absorption (K, B5, biotin) from microbiome

22
Q

coecum

A

pouch where entry is controlled by ileocecal valve
appendix and vermiform appendix

23
Q

what mesentery supplies the appendix and vermiform appendix

A

meso-appendix mesentery

24
Q

colon

A

ascending, transverse, descending, sigmoid
haustra allow expansion and elongation
attached to omental appendices (pouches of fat)

25
what create haustra of large intestine
taeniae coli smooth muscle
26
ascending colon
from coecum bends right at hepatic flexure
27
transverse colon
bends left at splenic flexure
28
descending colon
reaches iliac fossa firmly attaches to abdominal wall
29
sigmoid colon
S shaped empties into rectum
30
blood supplies of the colon
superior and inferior mesentery arteries and veins
31
histology of colon
large lymphoid nodules at lamina propria muscular layer - taeniae coli lacks villi goblet cells (mucous)
32
rectum epithelium
faeces storage anal canal contains longitudinal folds transitions from columnar epithelium to stratified squamous epithelium anus is keratinised
33
anal sphincters
internal: involuntary external: voluntary
34
what can occur due to the lamina propria of the rectum being highly vascularised with veins
haemorrhoids