Gastrointestinal system Flashcards

Rebecca

1
Q

what is the primary function of the GI tract

A

absorption of dietary nutrients maximised by secretions added to convert large molecules to smaller ones

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2
Q

what are the other GI functions

A

storage and secretion

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3
Q

what is the mucosa made up of and where is it found

A

epithelium, lamina propria, muscularis mucosa

nearest the lumen, inside

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4
Q

what is lamina propria

A

CT , has nerves, blood and lymph vessels

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5
Q

what is the muscularis mucosa

A

thin layer of smooth muscle

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6
Q

what is the submucosa layer and where

A

thicker layer with similar composition to lamina propria (CT)
contains submucosal plexus
middle

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7
Q

what is the muscularis externa

A

circular muscle, myenteric plexus and longitudinal muscle

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8
Q

what does the ENS do

A

coordinates contractions to mix and move contents between compartments

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9
Q

what is the serosa layer

A

outmost layer of CT and squamous cells

some tract sections dont have this layer

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10
Q

what 3 divisions of the ANS regulate the Gi function

A

parasympthetic
sympathetic
enteric

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11
Q

what does the PNS do

A

signals stimulate GI secretions and motility facilitating digestion and absorption of nutrients

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12
Q

what does the SNS do

A

decreases GI secretions and motility

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13
Q

how does the ENS work

A

can operate independenly and is involved with reflexes and majority of GI functions

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14
Q

what are the main plexuses in the ENS

A

myenteric

submucosal

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15
Q

what does the myenteric plexus do

A

motility

regulates intestinal smooth muscle , contractions of muscles

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16
Q

what is motility

A

coordinated contraction and relaxtion of muscles in the Gi tract

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17
Q

what does the submucosal plexus do

A

secretions, regulates secretions and local absoptive environment

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18
Q

what do reflexes in the ENS do

A

If one thing is going onn in one place then it can influence whats happening in another part

19
Q

how do they reflexes in the ENS communicate?

A

they are neural circuits with mechanoreceptors or chemoreceptors that then causes nerves to signal to regulate endocrine or secretory cells

20
Q

what are some GI neurotransmitter examples

A

enkephalins (contrict circular muscle around sphincters), ACh, serotonin

21
Q

what are some GI hormones (endocrine)

A

gastrin, cholecystokinnin, motilin, secretin

22
Q

what are paracrines

A

hormones released that act locally

23
Q

examples of paracrines

A

histamine, prostaglandins , somastostatin

24
Q

what are the 3 digestive phases

A

cephalic phase, gastric phase and intestinal phase

25
what is the cephalic phase
triggered by thought of food , primarily neural, stimulates secretion
26
what is the gastric phase
begins when food and oral secretions enter the stomach, coincides with distension (expansion of stomach). hormonal, neural and paracrine
27
what is the intestinal phase
when stomach contents recah the duodenum | primarily hormonal but also other 2
28
what is the role of the upper GI tract
minimal role in nutrient absorptionm transports and prepares food to be absorbed
29
parts of the upper GI tract
mouth, salivary glands, oesophagus,stomach
30
what does the mouth do
reduces food to optimal size, mixes food with secretions from 3 salivary glands (submandibular, parotid, sublingual)
31
what is mastication
chewing
32
swallowing (oesophagus)
- intiated voluntarily, involuntary after - parasympathetic - from mouth to upper oesophageal sphincter
33
peristalsis in the oesophagus
series of coordinated muscle contraction/relaxtion | commences after upper oesopheageal sphincter
34
functions of the stomach
3 primary motility functions mixing via slow wave-intiated contractions, retropulsion and gastric emptying accept and store food mix food with secretions digest food deleiver food to small intestine
35
stomach secretions
dervived from gastric invaginations (pits) which contain multiple cell types to secrete different secretions
36
how do salivary secretions get produced
controlled by sympathetic and parasympathetic cl, na and water are transported to duct lumen ductal cells modify by reabsorbing na and cl and secreting K and HCO3 -
37
examples of gastric secretions
ions and water, mucus from mucous neck cells, pepsinogen from cheif cells , H+ from parietal cells
38
what are the sections of the small intestine
duodenum jejunum illeum
39
what is the role of the small intestine
most macronutrient , vitamin and mineral absorption occurs (big SA)
40
what are the parts of the large intestine
caecum, ascending, transverse, descending and sigmoid colon rectum anus
41
role of large intestine
significant water and ion absoprtion | motility of contents :mixing and propulsion
42
waht does motility in the small intestine involve
mixing via segementation and propulsion via peristalsis
43
what does motility in the large intestine involve
segementation, peristalsis and mass movement and reflexes that control sphincter contraction and relxation
44
what does the ileocecal sphincter regulate
amount of chyme entering the large intestine