Gastrointestinal System Q4 Flashcards

(43 cards)

1
Q

ID structures

A
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2
Q

What are the 3 layers of the mucosa?

A

Epithelium, lamina propria, and muscularis mucosa.

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3
Q

What layer is deep to the mucosa and what type of tissue is it?

A

Submucosa. Dense irregular CT.

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4
Q

What three layers make up the muscularis externa layer?

A

Inner circular layer, myenteric nerve plexus, and outer longitudinal layer.

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5
Q

What is the structure found between the inner circular and the outer longitudinal layers of the muscularis externa?

A

Enteric plexus.

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6
Q

What is the outer layer of the GI tract?

A

It is adventitia CT but when covered with mesothelium it is serosa.

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7
Q

When will an organ have adventitia?

A

When it is connecting to another organ.

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8
Q

What is mesothelium?

A

Simple squamous epithelium lining CT of GI tract whenever organs are not touching.

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9
Q

What are the three layers of the pharynx?

A

1- Mucosa made of non-keratinized stratified squamous and lamina propria. (no muscularis mucosa/submucosa)

2- Muscularis externa: Circular and longitudinal

3: Adventitia: outer CT.

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10
Q

How can you tell the vagina apart from the esophagus?

A

The presence of esophageal glands in the submucosa and lamina propria.

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11
Q

What is the structure where the esophagus and stomach meet and what is this structure formed by??

A

The esophageal sphincter. Formed from the smooth muscle of the muscularis externa.

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12
Q

At the junction of the esophagus and stomach, what type of epithelium will be present?

A

It will transition from stratified squamous to simple columnar.

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13
Q

What is the function of lipase and pepsin?

A

Lipase is to break down carbohydrates and pepsin to break down proteins.

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14
Q

What are the “indentations” in the mucosa of the stomach?

A

Gastric pits that lead to gastric glands.

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15
Q

What layer of the stomach contracts to break mix the chyme?

A

Muscularis externa.

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16
Q

In the cardia, body/fundus, and pylorus explain the differences in the pits and glands.

A

Cardia pits shorter than glands. Body/Fundus long glands but pits more defined than cardia. Pylorus longer pits and shorter glands.

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17
Q

What are the type of glands of the cardia?

A

Mucous glands

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18
Q

What type of cells are in the glands of the body/fundus?

A

Cheif cells which secret pepsin and lipase, and parietal cells that secret gastric acid and intrinsic factor.

19
Q

What are the primary type of glands in the pylorus?

A

Mucous glands.

20
Q

What do D cells of the stomach release?

A

Somatostatin.

21
Q

What do G cells of the stomach release?

A

Gastrin stimulating acid.

22
Q

Where are the stem cells of the glands found?

A

At the top in the isthmus.

23
Q

What is the difference between surface mucous cells and mucous neck cells?

A

Surface secrete alkaline fluid while neck secrete acidic fluid.

24
Q

Where do cheif cells secrete their enzymes?

A

Lumen side of the gut.

25
What cells are part of the DNES? Where do their secretions go?
G cells. diffuse neuroendocrine system cells secrete all sorts of things. Into the blood to be able to communicate to the rest of the body.
26
What nerve is responsible for the regulation of HCl secretion?
Vagus nerve.
27
Where is the site of most chemical digestion?
Duodenum.
28
Where does the absorption of bile-lipid micelles take place?
Ileum.
29
What three structures are responsible for increasing the surface area of the small intestine?
Plica circulares (3x), vili (10x), and microvili (20x).
30
What layers make up plica circulares?
Mucosa and submucosa.
31
What makes up the vili?
Lamina propria and covered in simple columnar epithelium.
32
What makes up the microvili?
The folding of individual cell membranes.
33
What do brunners glands secrete and where are they located?
Found in the duodenum and secrete mucus.
34
What are peyer's patches made of?
Lymphoid tissue.
35
What is MALT refering to?
Mucosal Associated Lymphatic Tissue where specialized epithelial cells endocytos antigens to bring to lymphocytes and dendritic cells.
36
What are enterocytes?
Absorptive columnar cells.
37
How does the absorption of lipids take place?
Bile acids emulsify them to be broken down by gastric lipase then allowing them to diffuse across membrane to SER and to RER to LYMPHATICS and end up in the tissues.
38
How does the absorption of protein and carbohydrates take place?
enterocytes release disaccharidases and amino peptidases breaking down into monosac and amino acids allowing to be absorbed via active co transport and released into CAPILLARIES.
39
What is the effect of cholera?
Pushes Cl into the lumen of the gut destrying the osmotic gradient and water absorption.
40
What cells are the innate immune cells and what do they release?
Paneth cells located in the crypts of lieberkuhn and release lysozyme, phospholipase A, and defensins.
41
What is the function of enteroendocrine cells?
Help the GI tract keep track of how much of what is where by secreting scretin, CCK, and GIP.
42
What is the function of the submucosa and muscularis externa for intestinal motility?
Submucosa moves vili and plica ciruclarae for mixing and the mucularis externa primary source of motility.
43
What is the myenteric plexus?
collection of sympathetic and parasympathetic nerve fibers that regulate GI.