GEN SURG part 2 Flashcards

(54 cards)

1
Q

Norm Na levels in serum

A

135-145

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2
Q

Norm K levels in serum

A

3.5-5

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3
Q

Norm Ca levels in serum

A

2.2-2.6

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4
Q

Norm Cl levels in serum

A

94-111

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5
Q

Norm lactate levels in serum

A

1-2

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6
Q

Composition of 0.9% saline

A

OSM: 308
Na+ - 154
Cl- 154

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7
Q

Composition of 4% dextrose 0.18% saline

A

OSM: 283
Na 30
Cl 30
40g dextrose in 1 L h20

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8
Q

Composition of Hartmanns

A
OSM 278 
Na 131
K 5
Ca 2+ 2
CL 111
Lactate 29
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9
Q

Composition of Gelatine 4%

A

OSM 290
Na 145
Cl 145

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10
Q

Composition of 5% albumin

A

OSM 300
Na 150
Cl- 150

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11
Q

Which solutions are ‘colloids’

A

Gelatin

Albumin

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12
Q

Why do colloids not work like they do in theory

A

ill pt have leaky vessels so are not as effective

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13
Q

Other -ves of colloids (2)

A

Expensive

Cause anaphylaxis/allergies

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14
Q

If you give a 70kg man 1L of pure water, how much ends up in the plasma

A

83ml

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15
Q

If you give isotonic solutions, what % ends up in the ECG

A

100%

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16
Q

If you give a 70kg man 1L of isotonic solution, how much ends up in plasma

A

250ml

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17
Q

E.g.s of ‘sensible’ losses

A

Urinary losses

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18
Q

E.g.s of insensible losses ‘3’

A

Sweat
Lungs
Faeces

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19
Q

E.g.s of ‘additional’ losses (4)

A

NG tubes
Stomas
Drains
3rd space losses

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20
Q

What is the ‘third space’

A

Cavities where fl does not normally collect and is not readily exchangable

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21
Q

Egs of third spaces (3)

A

GIT
Pleura
Peritoneum

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22
Q

How many ml lost via urine a day

23
Q

How many ml lost by lungs and faeces a day

24
Q

How many ml lost by sweating a day

25
how many L of fl does an ill pt in hospital need /day
3L
26
1 salty 2 sweet regimen
1L norm saline +20mmol KCl over 8h 1L 5% dextrose w/ 20mmol KCl over 8h 1L 5% dextrose w/ 20mmol KCl over 8h
27
What must you ALWAYS do before prescribing fl
Chekc U+E
28
If pt has pyrexia, how does fl regime change
+ 10% for ever degree of fever
29
What activates the RAAS
Decreased effective aa blodo volume --> decreased renal blod flow Or By unloading of high pressure baroceptors in the aa system
30
Where are the baroceptors (3)
LA Carotid body Aortic arch
31
What deactivates the RAAS
Increaseed EABV --> stretch atrial myocardium --> release of ANP ANP vasodilates renal aaa _ decreasees RAAS activity
32
sx of mild dehydration (3)
Headache lack of E Tired
33
sx of mod dehydration (4)
Dry mouth Decr alertness Sunken eyes Mm cramps
34
Sx of severe dehydration (5)
``` Confusion Disorientation TachyC Tachypnoea Low BP ```
35
Blood results dehydration
Deranged U+E | Markedkly raised urea
36
metabolic change vomiting
Hypochloraemic, hypokalaemia metabolic alkalosis
37
Tx vomiting
0.9% saline | + 20mmol KCl
38
What do pancreatic, small bowel, and bile fistulas contain
High bicarbonate levels
39
How much K levels seem with these fistulae and why
Elevated (due to acidosis desplaces K from cells) | But really total body K is depleted
40
Metabolic changes in acute diarrhoea
Hyperchloraemic metabolic acidosis | Hypokalaemia if profuse
41
Tx diarrhoea if oral rehydration not possible
0.9% saline | 20mmol K
42
Fl Mx stable pt w/ closed head injury
⅔ of maintenance isotonic solutions
43
Metabolic changes ATN (6)
``` Hyperkalaemia Hyperphosphataemia Hypermagnesia Hyponatraemia Hypocalcaemia Metabolic acidosis ```
44
Essential Ix for dehydration
``` FBC U+E Lactate GLucose Urinalysis ```
45
What is SIADH
Non-physiological release of ADH | --> DECREASED water excretion + normal Na excretio --> dilutional hyponatraemai
46
causes if SIADH (broad categories) | 6
``` Malignancy CNS disorders Chest disease Endocrine disease (hypothyroidism) Drugs Other ```
47
Malignancies --> SIADH (3)
Small cell lung Pancreas Prostate
48
CNS disorders --> SIADH (3)
Meningoencephalitis Haemorrhage Head injury
49
Chest conditions --> SIADH (3)
TB Pneumonia Abscess
50
Drugs --> SIADH (2)
Opiates | Psychotropics
51
Ix SIADH
Hyponatraemia Norm Urea/creatinine Incr urinary sodium hence incr specific gravity urine
52
Def diabetes insipidus
Passage of large vol of dilute urine b/c imp water resorption by kidneys collecting ducts
53
What causes diabetes insipidus
reduced ADH secretion from post pit OR impaired response of kidney
54
Consequence of diabetes insipidus
Hypernatraemia | Raised plasma osmolality