General

Question 1

CD5 expression during thymic maturation

Answer 1

Rises steadily, and the lever reflects the amount of signaling recieved by cells. Both TCR levels and intensity influence CD5 expression on thymocytes.

Question 2

CD69 expression in the thymus

Answer 2

Induced within 4 hours of productive TCR engagmement by ligands presented on thymic stromal cells. It occurs during both positive and negative selection