genes and behaviour Flashcards

1
Q

do all genomes code for proteins?

A

no only a tiny proportion do

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2
Q

relationship between amount of dna and complexity of organism?

A

no clear relationship

may have lots of chromosomal dna but not be very complex

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3
Q

what % of our dna do we share with other humans and with chimpanzees and mice?

A

humans - 99.8%
chimpanzees - 98%
mice - 92%

similarity due to bodies doing largely the same things

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4
Q

what is a genotype?

A

set of genes individual possesses

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5
Q

what is a phenotype?

A

observable characteristics of an individuals

influenced by genes and enviro

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6
Q

what is an allele?

how many do individuals have compared to population?

A

a variant of a gene which determines 74% variance

have 1 or 2 of each gene but multiple can exist in population

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7
Q

what does it mean if genes on same chromosome?

A

inherited together

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8
Q

what is meant by the fact that humans are ‘diploid’?

A

2 copies of each chromosome (1 from mum and dad)

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9
Q

describe the difference between homo and heterozygous?

A

homozygous - 2 of the same allele so will express those alleles

heterozygous - different alleles from mum and dad so will express the dominant allele

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10
Q

describe the agouti gene?

A

influences coat pattern in mammals fur

alleles inherited determine colour of coat

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11
Q

what are lethal alleles?

A

lead to death of homozygous recessive offspring

e.g 2 copies of yellow coat gene (recessive) from heterozygous parents lead to death of mice as embryos

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12
Q

what is polygenic inheritance?

A

multiple different genes involved in inheritance

leads to additive genetic variance

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13
Q

describe polygenic inheritance of human skin colour?

A

alleles A B and C dominant correspond to more melanin so darker skin pigmentation

alleles a b and c recessive correspond to less melanin so light pigmentation

each parents produces 8 gametes which combine with each other in 64 different ways and results in total of 7 skin colours

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14
Q

name some challenges to behavioural genetics research?

A

difficult in defining and quantifying beh. compared to physical traits e.g eye colour

enviro influences on beh. - social and physical

may genes involved

variance within and between individuals - different beh. at different times

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15
Q

describe the burrow structure of mice behaviour related to their genes?

A

deer mouse

  • no escape tunnel
  • homozygousfor recessive alleles which don’t cause building of tunnels

oldfield mouse

  • escape tunnel due to predation
  • homozygous for allelels which cause building of escape tunnel

when crossbread 100% build escape tunnels (suggests allele for building tunnel dominant)

crossbread again with deer mouse 50% built escape tunnels so controlled by single gene

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16
Q

describe foraging in fruit-fly larvae describing relationship between genetics and behaviour?

A

rover (move) and sitter (stay) in search for food expressed through single gene (not coded)

F1 offspring (1st crossbread rover - dominant and sitters - recessive) all were rovers

crosshybrid offspring with each other (F2) and 3(rover):1(sitter) which displays that rover is dominant but much be 1 homozygous recessive sitter offspring

17
Q

describe maternal behaviour in mice as showing behaviour related to genetics?

A

fosB mutation in mice causes disruption of maternal behaviour

fosB gene expressed in peroptic area of hypothalamus so fosB deficient mice only influence in maternal behavioour (not pleiotropic effect)

18
Q

what can expression of a gene influence and what influences it?

A

acts on different phenotypic levels and influenced by environment at each stage e.g diet:

expression of other genes
activity of the cell, tissues and organs
developmental processes
activity of brain, muscles and messenger systems (behaviour)

19
Q

what are traits determined by?

A

genes and enviro in conjunction

so continuous variation

20
Q

what can quantitative traits be?

A

morphological - height
physiological - hormone
behavioural

21
Q

what is meant by ‘norm of reaction’?

A

pattern of phenotypic expression of a single genotype across a range of environments

22
Q

what does total phenotypic variance based on?

A

Vt = Vg + Ve

phenotypic variance = additive effects of genetic variance (Vg) + environmental variance (Ve)

23
Q

what is trait heritability?

equation and description?

A

h^2=genetic variance / total variance in that trait

proportion of phenotypic variation which is associated wih genetic variance

24
Q

what is the equation for aritificial selection of heritable traits?

A
h^2 = R/S
R = response to selection
S= strength of selection

if h^2=1 then full resemblance

25
give an example of effects of genotype being masked by environmental effects?
enriched environment improves performance of maze dull rats but restricted environment prevents expression of inherited ability no longer masked when environment fair
26
when are alleles termed wild-type or mutat?
mutant when frequency <1% | wild-type when >1%
27
when are genes known as monomorphic and polymorphic?
mono - gene with 1 wild-type allele | poly - gene with >1 wild-type allele
28
difference between germ-line and somatic mutation?
germ-line in sperm/egg cells so gametes produced will contain mutation somatic not in sex cells so not transferred to next generation
29
what may increase mutation above spontaneous levels?
mutagens e.g oxidative radicals radiation
30
example of genetic mutation's impact on behaviour?
social amnesia males unable to produce oxytocin then inspects same female mouse for the same amount of time as if unfamiliar
31
what does monozygotic mean?
developed from same zygote (fertilised egg)
32
how to use twins to show genetic effects on behaviour?
high correlation in behaviour when monozygotic twins living apart in different environment as only thing they share is 100% of the same genes
33
what is the relationship between genes and behaviour?
genes produce proteins which can influence behaviour through effects on e.g neurons and hormones resulting behaviour affected by environmental conditions in which it develops
34
where are genes located?
located on chromosomes (DNA coiled around histones) located in the cell nucleus
35
which 2 processes are involved in gene expression?
1. transcription - dNA copied to RNA using RNA polymerase enzyme 2. translation - mRNA decoded in ribosome to produce specific amino acid chain
36
what are the products of genes and what can they be used for?
product = proteins complex, large molecules doing most of work in cell: forming antibodies, enzymes, hormones, structual components and transport/storage