Genetic and immunologic principles

Question 1

1. The normal human cell contains ____ pairs of chromosomes.
   a. 12
   b. 23
   c. 46
   d. 92

Answer 1

b. 23

Question 2

2. A gamete would contain ____ chromosomes.
   a. 23 pairs of
   b. 46 pairs of
   c. 23
   d. none of the above

Answer 2

d. none of the above

Question 3

3. Eggs and sperm are formed through the process of
   a. mitosis
   b. meiosis
   c. linkage
   d. crossing-over

Answer 3

b. meiosis

Question 4

4. With which of the following would an anti-K showing dosage react most strongly?
   a. a red cell of the genotype Kk
   b. a red cell of the genotype kk
   c. a red cell of the genotype KK
   d. none of the above

Answer 4

c. a red cell of the genotype KK

Question 5

5. If the frequency of gene Y is 0.4 and the frequency of gene Z is 0.5, one would expect they should occur together 0.2 (20%) of the time. In actuality, they are
   found together 32% of the time. This is an example of
   a. crossing-over
   b. linkage disequilibrium
   c. polymorphism
   d. linkage equilibrium

Answer 5

b. linkage disequilibrium

Question 6

6. A gene that produces no detectable product is referred to as
   a. an amorph
   b. a trait
   c. an allele
   d. a polymorph

Answer 6

a. an amorph

Question 7

7. Alternate forms of a gene that can occur at a single chromosome locus are referred to as
   a. traits
   b. alleles
   c. chromosomes
   d. phenotypes

Answer 7

b. alleles

Question 8

8. Which of the following describes the expression of most
   blood group genes?
   a. dominant
   b. recessive
   c. codominant
   d. corecessive

Answer 8

c. codominant

Question 9

9. For a trait to be useful as a genetic marker, which of the
   following is important?
   a. a simple and unequivocal pattern of inheritance
   b. lack of polymorphism
   c. regular interaction with other genes that alter its
   expression
   d. none of the above

Answer 9

a. a simple and unequivocal pattern of inheritance

Question 10

10. A gene found only in a few individuals, usually in a particular race or family, is referred to as:
    a. an amorphic gene
    b. a public gene
    c. a private gene
    d. a genetic aberration

Answer 10

c. a private gene

Question 11

11. True or false? A standard nomenclature used uniformly
    for all blood group systems exists.

Answer 11

false

Question 12

12. True or false? An individual who is group A cannot
    product a child who is group B

Answer 12

false

Question 13

13. True or false? Genes located far apart on the chromosome are more likely to cross over, resulting in changed
    genetic information.

Answer 13

True

Question 14

14. True or false? In a direct exclusion, the child has failed
    to inherit a gene that should have been passed by the
    alleged father.

Answer 14

false

Question 15

15. True or false? Some genes can inhibit the expression of
    other genes.

Answer 15

True