Genetics

Question 1

___________produces four gametes having half the number of chromosomes present in the parent cell

Answer 1

Meiosis

Question 2

_________leads to two daughter cells having the same number of chromosomes as the parent cell.

Answer 2

Mitosis

Question 3

When a male possesses a phenotypic trait that he passes to all of his daughters and none of his sons, the trait is said to be X-linked________.

Answer 3

Dominant

Question 4

Trait appears in every generation with no skipping

Answer 4

Autosomal dominant

Question 5

Incidence of the trait is much higher in males than in females

Answer 5

X-linked recessive

Question 6

Trait is passed from an affected man through all of his daughters and half of his sons.

Answer 6

X-linked recessive

Question 7

Affected males transmit the trait to all of their daughters and none of their sons.

Answer 7

X-linked dominant

Question 8

The parents of the affected child may be consanguineous.

Answer 8

Autosomal recessive

Question 9

Trait characteristically appears only in siblings, not in their parents, offspring or other relatives

Answer 9

Autosomal recesssive

Question 10

1. What do p and q represent in the Hardy-Weinburg formula?
2. What do p2, 2pq and q2 represent?

Answer 10

1. Gene frequencies
2. Phenotypes

Question 11

What antigens are in the P1Pk system?

Answer 11

P1, Pk and NOR

Question 12

1. What antigens does a P1 + person have on their red blood cells
2. What antibodies can they form?

Answer 12

1. P1, P and Pk
2. They will not make antibodies

Question 13

1. What antigens does a P2 positive person have on their red blood cells
2. What antibodies can they form?

Answer 13

1. P and Pk
2. Anti-P1

Question 14

1. What antigens does a P1k positive person have on their red blood cells
2. What antibodies can they form?

Answer 14

1. P1, P1k
2. Anti-P

Question 15

1. What antigens does a P2k positive person have on their red blood cells?
2. What antibodies can they form?

Answer 15

1. Pk only
2. Anti-P (possibly anti-P1)

Question 16

1. What antigens does a p person have on their red blood cells
2. What antibodies can they form?

Answer 16

1. No P, P1 or Pk
2. Anti-P, P1, Pk (Tja)

Question 17

True or False: Cord blood cells are Le(a-b-)

Answer 17

True

Question 18

In order to have Lewis antigens on the red cell, the individual must have the ____ and ____ gene.

Answer 18

Se (FUT2) and Le (FUT3)

Question 19

Wiener makes me whine and you have to memorize this one!

Answer 19

R1-DCe
R2-DcE
Ro-Dce
Rz-DCE
_r’-dCe
-r‘’-dcE
-r-dce
-ry-dCE

Question 20

What is the relative order of frequency of the common Rh haplotypes in Whites and Blacks?

Answer 20

Whites-R1>r>R2>R0
Blacks-R0>r>R1>R2

R1 always >prevalence over R2

Question 21

-Trait characteristically appears only in siblings, not in their parents, offspring or other relatives
-On average, one fourth of the siblings of the propositus are affected
-males and females are equally likely to be affected

Answer 21

Autosomal recessive

Question 22

-Affected males transmit trait to all their daughters and to none of their sons
-Affected females who are heterozygous transmit the condition to half their children of either sex
-Affected females who are homozygous transmit the condition to all their children

Answer 22

X linked dominant

Question 23

-Trait appears in every generation, with no skipping
-Trait is transmitted by an affected person to half the children on average
-Unaffected persons do not transmit the trait to their children
-males and females equally likely to have or to transmit the trait

Answer 23

Autosomal dominant

Question 24

-Incidence of the trait is much higher in males than in females
-Trait is passed from an affected male through all his daughters to half of their sons
-Trait is never transmitted directly from father to son
-Trait may be transmitted through a series of female carriers; if so the affected males may skip generations

Answer 24

X-linked recessive