Genetics Flashcards

1
Q

Define gene

A

Seq. of bases on DNA that codes for protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define allele

A

Diff. version of a gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Define genotype

A

Genetic makeup of an organism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Define phenotype

A

Expression of genotype + it’s interactions w/ the env

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Define dominant

A

Allele whose characteristic appears in phenotype even when there’s only 1 copy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Define recessive

A

Allele whose characteristics appear if 2 copies are present

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Define codominant

A

Alleles both expressed in the phenotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Define locus

A

Fixed position of a gene on c’some

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Define homozygote

A

Organism that carries same allele

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Define heterozygote

A

Organism that carries 2 diff alleles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Define carrier

A

Person carrying allele which is not expressed in phenotype but can be passed onto offspring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Humans are diploid organisms. What does this term mean?

A

2 alleles for each gene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the phenotypic ratio in a monohybrid btw homo dom + homo rec? (RR x rr)

A

3:1

Dominant : Recessive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the phenotypic ratio in a dihybrid btw hetro? (RrYy x RrYy)

A

9 : 3 : 3 : 1

Dom : Hetro : Hetro : Rec

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

When are characteristics described as sex-linked?

A

Allele that codes for characteristic is located on sex c’some

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the sex c’somes in females?

17
Q

What are the sex c’somes in males?

18
Q

Outline a diff. btw Y c’somes and X c’somes

A

Y is smaller so carriers fewer genes

19
Q

Why are males more likely to show recessive phenotype for sex-linked genes?

A

Males only have one X c’some, often have 1 allele so express characteristic even if recessive

20
Q

Define autosome

A

C’somes that aren’t sex c’somes

21
Q

Why are genes on the same autosome said to be linked?

A

Same autosome stay together during independent segregation + passed onto offspring

22
Q

When are autosomes not linked?

A

When crossing over occurs

23
Q

When are autosomal genes said to be more closely linked?

A

Closer together two genes are on autosome bc crossing over is less likely to split them up

24
Q

Define epistatis

A

Allele of one gene masks the expression of the alleles on the other genes

25
What is the chi-squared test used for?
Test to **compare** the goodness of fit of observed + expected results
26
Chi-squared value is larger than or equal to critical value
* **Significant diff.** * **Less** than **5% probability** diff. due to **chance** * **Reject null**
27
Chi-squared value is smaller than or equal to critical value
* **No significant diff.** * **More** than **5% probability** diff. due to **chance** * **Accept null**
28
How do you work out the chi-squared value?
**(O-E)2 / E** * O = **observed** * E = **expected**
29
After working out the chi-squared value, what do you do?
* **Degrees of freedom** - **no. classes minues 1** * **Critical value** at probability of **0.05** * **Compare** critical w/ chi-squared value